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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              18    1135
NP_001243397                                                           18    1135
XP_005269721                                                           18    1135
XP_005274178                                                           17    3301
XP_005274177                                                           17    3301
XP_005274175                                                           17    3301
NP_065731                                                              17    3301
NP_001041683                                                           17    3301
NP_112196                                                              16    5631
NP_001575                                                              16    5631
NP_001189352                                                           16    5631
XP_005253170                                                           16    5631
XP_006718367                                                           16    5631
XP_005253169                                                           16    5631
XP_005253168                                                           16    5631
XP_005253167                                                           16    5631
NP_001138498                                                           16    7355
NP_073747                                                              15    9605
NP_073577                                                              15    9605
NP_001106710                                                           15    9605
NP_001269105                                                           15    9605
NP_001269104                                                           15    9605
NP_001285                                                              15    9605
XP_006715999                                                           15    9605
XP_006715998                                                           15    9605
XP_006715997                                                           15    9605
XP_005271187                                                           15    9605

>NP_036462
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TYISASTRK 9
           TYISAST K
Sbjct: 418 TYISASTLK 426



>NP_001243397
          Length = 1890

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TYISASTRK 9
           TYISAST K
Sbjct: 418 TYISASTLK 426



>XP_005269721
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TYISASTRK 9
           TYISAST K
Sbjct: 418 TYISASTLK 426



>XP_005274178
          Length = 780

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TYISASTR 8
           +Y+SASTR
Sbjct: 457 SYLSASTR 464



>XP_005274177
          Length = 781

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TYISASTR 8
           +Y+SASTR
Sbjct: 457 SYLSASTR 464



>XP_005274175
          Length = 807

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TYISASTR 8
           +Y+SASTR
Sbjct: 457 SYLSASTR 464



>NP_065731
          Length = 808

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TYISASTR 8
           +Y+SASTR
Sbjct: 457 SYLSASTR 464



>NP_001041683
          Length = 791

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TYISASTR 8
           +Y+SASTR
Sbjct: 457 SYLSASTR 464



>NP_112196
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TYISASTRK 9
           +YI+AST K
Sbjct: 215 SYIAASTAK 223



>NP_001575
          Length = 294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TYISAST 7
           TYI+AST
Sbjct: 266 TYINAST 272



>NP_001189352
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TYISASTRK 9
          +YI+AST K
Sbjct: 59 SYIAASTAK 67



>XP_005253170
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TYISAST 7
           TYI+AST
Sbjct: 168 TYINAST 174



>XP_006718367
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TYISAST 7
           TYI+AST
Sbjct: 192 TYINAST 198



>XP_005253169
          Length = 294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TYISAST 7
           TYI+AST
Sbjct: 266 TYINAST 272



>XP_005253168
          Length = 294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TYISAST 7
           TYI+AST
Sbjct: 266 TYINAST 272



>XP_005253167
          Length = 294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TYISAST 7
           TYI+AST
Sbjct: 266 TYINAST 272



>NP_001138498
          Length = 2299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YISASTR 8
           Y++ASTR
Sbjct: 922 YVTASTR 928



>NP_073747
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   YISASTRK 9
           Y+S+S+RK
Sbjct: 326 YMSSSSRK 333



>NP_073577
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TYISAS 6
            TYISAS
Sbjct: 1171 TYISAS 1176



>NP_001106710
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TYISAS 6
            TYISAS
Sbjct: 1144 TYISAS 1149



>NP_001269105
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TYISASTR 8
           TYI +ST+
Sbjct: 360 TYIESSTK 367



>NP_001269104
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TYISASTR 8
           TYI +ST+
Sbjct: 448 TYIESSTK 455



>NP_001285
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TYISASTR 8
           TYI +ST+
Sbjct: 462 TYIESSTK 469



>XP_006715999
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TYISAS 6
            TYISAS
Sbjct: 1143 TYISAS 1148



>XP_006715998
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TYISAS 6
            TYISAS
Sbjct: 1164 TYISAS 1169



>XP_006715997
          Length = 1197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TYISAS 6
            TYISAS
Sbjct: 1170 TYISAS 1175



>XP_005271187
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   YISASTRK 9
           Y+S+S+RK
Sbjct: 200 YMSSSSRK 207



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.110    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 287,544
Number of extensions: 341
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)