Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           18    1482
NP_004439                                                              18    1482
NP_001276865                                                           18    1482
NP_001005862                                                           18    1482
XP_005257197                                                           18    1482
XP_006721828                                                           18    1482
NP_005219                                                              18    1935
NP_001036064                                                           18    1935
NP_005226                                                              18    1935
XP_005246434                                                           18    1935
XP_005246433                                                           18    1935
XP_005246432                                                           18    1935
XP_006712427                                                           18    1935
NP_004733                                                              16    5631
NP_001028229                                                           16    5631
NP_056335                                                              16    5631
XP_005265631                                                           16    5631
XP_006713477                                                           16    5631
XP_006713476                                                           16    5631
XP_005265628                                                           16    5631
XP_005265627                                                           16    5631
XP_006713475                                                           16    5631
XP_006713474                                                           16    5631
XP_005265625                                                           16    5631
XP_006713473                                                           16    5631
XP_005265623                                                           16    5631
XP_005265622                                                           16    5631
XP_005265621                                                           16    5631
XP_005265620                                                           16    5631
XP_006713472                                                           16    5631
XP_006713471                                                           16    5631
XP_006713470                                                           16    5631
NP_057336                                                              15    9605
XP_006712120                                                           15    9605
XP_005264512                                                           15    9605
XP_005264511                                                           15    9605
XP_006712119                                                           15    9605
XP_005264510                                                           15    9605
XP_006712118                                                           15    9605
XP_005264509                                                           15    9605
XP_005264508                                                           15    9605
XP_006712117                                                           15    9605
XP_005264507                                                           15    9605
XP_005264506                                                           15    9605
>NP_001276866
          Length = 1055

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQLV QLM
Sbjct: 793 TVQLVTQLM 801
>NP_004439
          Length = 1255

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQLV QLM
Sbjct: 793 TVQLVTQLM 801
>NP_001276865
          Length = 1240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQLV QLM
Sbjct: 778 TVQLVTQLM 786
>NP_001005862
          Length = 1225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQLV QLM
Sbjct: 763 TVQLVTQLM 771
>XP_005257197
          Length = 1225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQLV QLM
Sbjct: 763 TVQLVTQLM 771
>XP_006721828
          Length = 1336

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQLV QLM
Sbjct: 874 TVQLVTQLM 882
>NP_005219
          Length = 1210

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           TVQL+ QLM
Sbjct: 785 TVQLITQLM 793
>NP_001036064
          Length = 1292

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           T+QLV QLM
Sbjct: 791 TIQLVTQLM 799
>NP_005226
          Length = 1308

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           T+QLV QLM
Sbjct: 791 TIQLVTQLM 799
>XP_005246434
          Length = 1282

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           T+QLV QLM
Sbjct: 781 TIQLVTQLM 789
>XP_005246433
          Length = 1298

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           T+QLV QLM
Sbjct: 781 TIQLVTQLM 789
>XP_005246432
          Length = 1307

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           T+QLV QLM
Sbjct: 806 TIQLVTQLM 814
>XP_006712427
          Length = 1323

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVQLVIQLM 9
           T+QLV QLM
Sbjct: 806 TIQLVTQLM 814
>NP_004733
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 902 QLVVQLM 908
>NP_001028229
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 874 QLVVQLM 880
>NP_056335
          Length = 1287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 902 QLVVQLM 908
>XP_005265631
          Length = 1288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 902 QLVVQLM 908
>XP_006713477
          Length = 1290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 904 QLVVQLM 910
>XP_006713476
          Length = 1375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 786 QLVVQLM 792
>XP_005265628
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 874 QLVVQLM 880
>XP_005265627
          Length = 1425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 904 QLVVQLM 910
>XP_006713475
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 874 QLVVQLM 880
>XP_006713474
          Length = 1465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 876 QLVVQLM 882
>XP_005265625
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 890 QLVVQLM 896
>XP_006713473
          Length = 1479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 890 QLVVQLM 896
>XP_005265623
          Length = 1479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 902 QLVVQLM 908
>XP_005265622
          Length = 1481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 904 QLVVQLM 910
>XP_005265621
          Length = 1491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 902 QLVVQLM 908
>XP_005265620
          Length = 1492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 904 QLVVQLM 910
>XP_006713472
          Length = 1492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 903 QLVVQLM 909
>XP_006713471
          Length = 1492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 903 QLVVQLM 909
>XP_006713470
          Length = 1493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QLVIQLM 9
           QLV+QLM
Sbjct: 904 QLVVQLM 910
>NP_057336
          Length = 4857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2626 TSQLIIQL 2633
>XP_006712120
          Length = 4812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2581 TSQLIIQL 2588
>XP_005264512
          Length = 4840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2609 TSQLIIQL 2616
>XP_005264511
          Length = 4847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2653 TSQLIIQL 2660
>XP_006712119
          Length = 4851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2620 TSQLIIQL 2627
>XP_005264510
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2630 TSQLIIQL 2637
>XP_006712118
          Length = 4864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2653 TSQLIIQL 2660
>XP_005264509
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2639 TSQLIIQL 2646
>XP_005264508
          Length = 4875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2644 TSQLIIQL 2651
>XP_006712117
          Length = 4878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2647 TSQLIIQL 2654
>XP_005264507
          Length = 4880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2649 TSQLIIQL 2656
>XP_005264506
          Length = 4884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVQLVIQL 8
            T QL+IQL
Sbjct: 2653 TSQLIIQL 2660
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.145    0.338 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 264,188
Number of extensions: 402
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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