Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005492                                                              16    5631
NP_002195                                                              16    5631
NP_001119580                                                           16    5631
NP_000330                                                              16    5631
NP_001119579                                                           16    5631
XP_005257365                                                           16    5631
XP_005256176                                                           16    5631
NP_004254                                                              16    7355
NP_001258591                                                           16    7355
NP_620168                                                              16    7355
NP_006086                                                              16    7355
NP_001098999                                                           16    7355
NP_004663                                                              16    7355
NP_001171473                                                           16    7355
XP_006722719                                                           16    7355
XP_006722718                                                           16    7355
XP_006722717                                                           16    7355
XP_006715629                                                           16    7355
XP_006714052                                                           16    7355
XP_005248100                                                           16    7355
XP_006711982                                                           16    7355
XP_005246086                                                           16    7355
NP_078970                                                              16    7355
NP_005106                                                              15    9605
NP_059447                                                              15    9605
NP_055021                                                              15    9605
>NP_005492
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TV+T A GR
Sbjct: 900 TVLTCATGR 908
>NP_002195
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TV+T A GR
Sbjct: 900 TVLTCATGR 908
>NP_001119580
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           VITL +GR
Sbjct: 974 VITLPIGR 981
>NP_000330
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           VITL +GR
Sbjct: 983 VITLPIGR 990
>NP_001119579
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           VITL +GR
Sbjct: 982 VITLPIGR 989
>XP_005257365
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TV+T A GR
Sbjct: 765 TVLTCATGR 773
>XP_005256176
          Length = 1020

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           VITL +GR
Sbjct: 973 VITLPIGR 980
>NP_004254
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           +IT AVGR
Sbjct: 201 IITRAVGR 208
>NP_001258591
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           +IT AVGR
Sbjct: 168 IITRAVGR 175
>NP_620168
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 932 VVTLAIG 938
>NP_006086
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 794 VVTLAIG 800
>NP_001098999
          Length = 1149

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 779 VVTLAIG 785
>NP_004663
          Length = 1288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TVI +A GR
Sbjct: 838 TVIEMATGR 846
>NP_001171473
          Length = 1263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 895 VVTLAIG 901
>XP_006722719
          Length = 1224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 856 VVTLAIG 862
>XP_006722718
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 942 VVTLAIG 948
>XP_006722717
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 942 VVTLAIG 948
>XP_006715629
          Length = 1667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TV+ L VGR
Sbjct: 739 TVVRLPVGR 747
>XP_006714052
          Length = 1000

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 630 VVTLAIG 636
>XP_005248100
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VITLAVG 8
           V+TLA+G
Sbjct: 794 VVTLAIG 800
>XP_006711982
          Length = 700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VITLAVGR 9
           +IT AVGR
Sbjct: 201 IITRAVGR 208
>XP_005246086
          Length = 1280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TVI +A GR
Sbjct: 830 TVIEMATGR 838
>NP_078970
          Length = 1667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVITLAVGR 9
           TV+ L VGR
Sbjct: 739 TVVRLPVGR 747
>NP_005106
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TVITLAVGR 9
           TV++L+ GR
Sbjct: 496 TVLSLSAGR 504
>NP_059447
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TVITLAVGR 9
           TV++L+ GR
Sbjct: 496 TVLSLSAGR 504
>NP_055021
          Length = 79

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TVITLAVG 8
          TV+ LA+G
Sbjct: 22 TVVLLAIG 29
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.141    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 330,606
Number of extensions: 525
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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