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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              19     665
NP_001243397                                                           19     665
XP_005269721                                                           19     665
NP_001575                                                              18    1482
XP_005253170                                                           18    1482
XP_006718367                                                           18    1482
XP_005253169                                                           18    1482
XP_005253168                                                           18    1482
XP_005253167                                                           18    1482
NP_060603                                                              16    7355
NP_001138889                                                           16    7355
NP_001245330                                                           16    7355
NP_001035049                                                           16    7355
NP_001245332                                                           16    7355
XP_006719763                                                           16    7355
XP_005266069                                                           16    7355
XP_006713747                                                           16    7355
XP_005247629                                                           16    7355
XP_005247628                                                           16    7355
NP_073591                                                              16    7355
NP_112233                                                              16    7355
NP_001934                                                              15    9605
NP_073577                                                              15    9605
NP_001106710                                                           15    9605
NP_000370                                                              15    9605
XP_006715999                                                           15    9605
XP_006715998                                                           15    9605
XP_006715997                                                           15    9605

>NP_036462
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTYISASTL 9
           +TYISASTL
Sbjct: 417 STYISASTL 425



>NP_001243397
          Length = 1890

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTYISASTL 9
           +TYISASTL
Sbjct: 417 STYISASTL 425



>XP_005269721
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTYISASTL 9
           +TYISASTL
Sbjct: 417 STYISASTL 425



>NP_001575
          Length = 294

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TTYI+AST
Sbjct: 265 TTYINAST 272



>XP_005253170
          Length = 196

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TTYI+AST
Sbjct: 167 TTYINAST 174



>XP_006718367
          Length = 220

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TTYI+AST
Sbjct: 191 TTYINAST 198



>XP_005253169
          Length = 294

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TTYI+AST
Sbjct: 265 TTYINAST 272



>XP_005253168
          Length = 294

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TTYI+AST
Sbjct: 265 TTYINAST 272



>XP_005253167
          Length = 294

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TTYI+AST
Sbjct: 265 TTYINAST 272



>NP_060603
          Length = 577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TT+++AST
Sbjct: 554 TTFLAAST 561



>NP_001138889
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TT+++AST
Sbjct: 480 TTFLAAST 487



>NP_001245330
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTYISASTL 9
           TT+I +STL
Sbjct: 651 TTFILSSTL 659



>NP_001035049
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTYISASTL 9
           TT+I +STL
Sbjct: 704 TTFILSSTL 712



>NP_001245332
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTYISASTL 9
           TT+I +STL
Sbjct: 651 TTFILSSTL 659



>XP_006719763
          Length = 800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTYISASTL 9
           TT+I +STL
Sbjct: 704 TTFILSSTL 712



>XP_005266069
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TTYISAST 8
          T Y+SA+T
Sbjct: 88 TAYVSATT 95



>XP_006713747
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TT+++AST
Sbjct: 480 TTFLAAST 487



>XP_005247629
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TT+++AST
Sbjct: 480 TTFLAAST 487



>XP_005247628
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTYISAST 8
           TT+++AST
Sbjct: 480 TTFLAAST 487



>NP_073591
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TTYISAST 8
           T Y+SA+T
Sbjct: 149 TAYVSATT 156



>NP_112233
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TTYISAST 8
           T Y+SA+T
Sbjct: 152 TAYVSATT 159



>NP_001934
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TTYISASTL 9
           T+Y++ ST+
Sbjct: 938 TSYVTGSTM 946



>NP_073577
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TYISAS 7
            TYISAS
Sbjct: 1171 TYISAS 1176



>NP_001106710
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TYISAS 7
            TYISAS
Sbjct: 1144 TYISAS 1149



>NP_000370
          Length = 1333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TYISASTL 9
           T+I ASTL
Sbjct: 235 TWIQASTL 242



>XP_006715999
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TYISAS 7
            TYISAS
Sbjct: 1143 TYISAS 1148



>XP_006715998
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TYISAS 7
            TYISAS
Sbjct: 1164 TYISAS 1169



>XP_006715997
          Length = 1197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    TYISAS 7
            TYISAS
Sbjct: 1170 TYISAS 1175



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.110    0.264 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 334,114
Number of extensions: 301
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)