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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              20     509
NP_001243397                                                           20     509
XP_005269721                                                           20     509
NP_001037835                                                           18    1935
NP_612504                                                              17    2528
NP_065776                                                              17    2528
XP_005250278                                                           17    2528
XP_006715966                                                           17    2528
XP_005250277                                                           17    2528
XP_006715965                                                           17    2528
XP_005250276                                                           17    2528
XP_006715964                                                           17    2528
XP_006715963                                                           17    2528
NP_001185744                                                           17    4312
XP_005275558                                                           17    4312
XP_005275391                                                           17    4312
XP_005275259                                                           17    4312
XP_005274965                                                           17    4312
XP_005272815                                                           17    4312
XP_005274885                                                           17    4312
XP_005248836                                                           17    4312
NP_689982                                                              16    7355
NP_620145                                                              16    7355
NP_775871                                                              16    7355
XP_006722779                                                           16    7355
XP_006722778                                                           16    7355
XP_005259585                                                           16    7355
XP_006722777                                                           16    7355
XP_006720088                                                           16    7355
XP_006720087                                                           16    7355
NP_115495                                                              15    9605
NP_073577                                                              15    9605
NP_001106710                                                           15    9605
NP_001273700                                                           15    9605
NP_115593                                                              15    9605
NP_942592                                                              15    9605
NP_001157934                                                           15    9605
XP_006715999                                                           15    9605
XP_006715998                                                           15    9605
XP_006715997                                                           15    9605
XP_005265728                                                           15    9605
XP_005265724                                                           15    9605

>NP_036462
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTTTYISAS 9
           TT+TYISAS
Sbjct: 415 TTSTYISAS 423



>NP_001243397
          Length = 1890

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTTTYISAS 9
           TT+TYISAS
Sbjct: 415 TTSTYISAS 423



>XP_005269721
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTTTYISAS 9
           TT+TYISAS
Sbjct: 415 TTSTYISAS 423



>NP_001037835
          Length = 326

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTTYISAS 9
           TTTY++AS
Sbjct: 296 TTTYVNAS 303



>NP_612504
          Length = 738

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 96  TTTTAVSAS 104



>NP_065776
          Length = 861

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>XP_005250278
          Length = 657

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TTTTYISAS 9
          TTTT +SAS
Sbjct: 4  TTTTAVSAS 12



>XP_006715966
          Length = 856

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>XP_005250277
          Length = 862

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>XP_006715965
          Length = 872

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>XP_005250276
          Length = 873

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>XP_006715964
          Length = 964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>XP_006715963
          Length = 975

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTTTYISAS 9
           TTTT +SAS
Sbjct: 220 TTTTAVSAS 228



>NP_001185744
          Length = 1773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1355 TTTVYITGS 1363



>XP_005275558
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>XP_005275391
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>XP_005275259
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>XP_005274965
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>XP_005272815
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>XP_005274885
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>XP_005248836
          Length = 1776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTT YI+ S
Sbjct: 1358 TTTVYITGS 1366



>NP_689982
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TTTTYI 6
          TTTTY+
Sbjct: 90 TTTTYL 95



>NP_620145
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TTTYISAS 9
           TT Y SAS
Sbjct: 301 TTAYFSAS 308



>NP_775871
          Length = 8384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TTTYISAS 9
            TTTYI  S
Sbjct: 6499 TTTYIGES 6506



>XP_006722779
          Length = 335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TTTTYI 6
           TTTTY+
Sbjct: 136 TTTTYL 141



>XP_006722778
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TTTTYI 6
           TTTTY+
Sbjct: 136 TTTTYL 141



>XP_005259585
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TTTTYI 6
          TTTTY+
Sbjct: 90 TTTTYL 95



>XP_006722777
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TTTTYI 6
           TTTTY+
Sbjct: 136 TTTTYL 141



>XP_006720088
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TTTYISAS 9
           TT Y SAS
Sbjct: 301 TTAYFSAS 308



>XP_006720087
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TTTYISAS 9
           TT Y SAS
Sbjct: 308 TTAYFSAS 315



>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TTTYISAS 9
            +TTY+S S
Sbjct: 5157 STTYLSTS 5164



>NP_073577
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TYISAS 9
            TYISAS
Sbjct: 1171 TYISAS 1176



>NP_001106710
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TYISAS 9
            TYISAS
Sbjct: 1144 TYISAS 1149



>NP_001273700
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTTT  SAS
Sbjct: 1857 TTTTSSSAS 1865



>NP_115593
          Length = 2603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTTT  SAS
Sbjct: 1970 TTTTSSSAS 1978



>NP_942592
          Length = 2352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTTT  SAS
Sbjct: 1719 TTTTSSSAS 1727



>NP_001157934
          Length = 5335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TTTTYISAS 9
           T TT+ SAS
Sbjct: 312 TPTTHFSAS 320




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 1474 TPTTHFSAS 1482




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 1723 TPTTHFSAS 1731




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 3031 TPTTHFSAS 3039




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 3280 TPTTHFSAS 3288




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 4114 TPTTHFSAS 4122




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 4363 TPTTHFSAS 4371




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            T TT+ SAS
Sbjct: 4556 TPTTHFSAS 4564



>XP_006715999
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TYISAS 9
            TYISAS
Sbjct: 1143 TYISAS 1148



>XP_006715998
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TYISAS 9
            TYISAS
Sbjct: 1164 TYISAS 1169



>XP_006715997
          Length = 1197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    TYISAS 9
            TYISAS
Sbjct: 1170 TYISAS 1175



>XP_005265728
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTTT  SAS
Sbjct: 1718 TTTTSSSAS 1726



>XP_005265724
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TTTTYISAS 9
            TTTT  SAS
Sbjct: 1969 TTTTSSSAS 1977



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295   0.0983    0.235 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 399,507
Number of extensions: 414
Number of successful extensions: 49
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)