Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              19     665
NP_001243397                                                           19     665
XP_005269721                                                           19     665
NP_001139416                                                           17    3301
NP_059131                                                              17    3301
NP_001139417                                                           17    3301
NP_001139418                                                           17    3301
XP_005253454                                                           17    3301
XP_005253453                                                           17    3301
XP_005253452                                                           17    3301
XP_005253451                                                           17    3301
XP_006720535                                                           17    4312
XP_005254948                                                           17    4312
XP_005254946                                                           17    4312
NP_001138516                                                           17    4312
NP_037404                                                              17    4312
NP_003881                                                              16    5631
NP_060686                                                              16    5631
NP_065073                                                              16    5631
XP_006715582                                                           16    5631
NP_005851                                                              16    5631
NP_079452                                                              16    7355
NP_076404                                                              16    7355
NP_061897                                                              16    7355
XP_005260736                                                           16    7355
XP_006723616                                                           16    7355
XP_006723615                                                           16    7355
XP_005260735                                                           16    7355
XP_005264436                                                           16    7355
XP_006712098                                                           16    7355
XP_006712097                                                           16    7355
NP_000126                                                              15    9605
NP_006437                                                              15    9605
NP_001486                                                              15    9605
NP_001158511                                                           15    9605
NP_001158510                                                           15    9605
NP_653297                                                              15    9605
NP_006791                                                              15    9605
NP_001273096                                                           15    9605
NP_001269103                                                           15    9605
NP_001180199                                                           15    9605
NP_523353                                                              15    9605
NP_006353                                                              15    9605
XP_005274497                                                           15    9605
XP_006724524                                                           15    9605
XP_005256351                                                           15    9605
XP_006721231                                                           15    9605
XP_006721230                                                           15    9605
XP_006718483                                                           15    9605
XP_006718482                                                           15    9605
XP_006718481                                                           15    9605
XP_006716390                                                           15    9605
XP_005273532                                                           15    9605
XP_005273531                                                           15    9605
XP_005273530                                                           15    9605
XP_006716389                                                           15    9605
XP_005273529                                                           15    9605
XP_006711224                                                           15    9605
XP_006711222                                                           15    9605
XP_006711221                                                           15    9605
XP_006711220                                                           15    9605
NP_941965                                                              15    9605
NP_940857                                                              15    9605
NP_001443                                                              15    9605
>NP_036462
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTSTYISA 8
           TTSTYISA
Sbjct: 415 TTSTYISA 422
>NP_001243397
          Length = 1890

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTSTYISA 8
           TTSTYISA
Sbjct: 415 TTSTYISA 422
>XP_005269721
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTSTYISA 8
           TTSTYISA
Sbjct: 415 TTSTYISA 422
>NP_001139416
          Length = 612

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 379 TYVSAC 384
>NP_059131
          Length = 712

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 497 TYVSAC 502
>NP_001139417
          Length = 663

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 448 TYVSAC 453
>NP_001139418
          Length = 730

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 497 TYVSAC 502
>XP_005253454
          Length = 590

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 497 TYVSAC 502
>XP_005253453
          Length = 612

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 379 TYVSAC 384
>XP_005253452
          Length = 633

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 418 TYVSAC 423
>XP_005253451
          Length = 712

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 497 TYVSAC 502
>XP_006720535
          Length = 594

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 492 TYLSAC 497
>XP_005254948
          Length = 595

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 377 TYLSAC 382
>XP_005254946
          Length = 697

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 492 TYLSAC 497
>NP_001138516
          Length = 692

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 492 TYLSAC 497
>NP_037404
          Length = 710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TY+SAC
Sbjct: 492 TYLSAC 497
>NP_003881
          Length = 5405

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    STYISAC 9
            +TY++AC
Sbjct: 2311 ATYVAAC 2317

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    STYISAC 9
            +TY++AC
Sbjct: 3512 ATYVAAC 3518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    STYISAC 9
            +TY++AC
Sbjct: 4713 ATYVAAC 4719
>NP_060686
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           +TYI AC
Sbjct: 98  NTYIEAC 104
>NP_065073
          Length = 2177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TYIS+C
Sbjct: 145 TYISSC 150
>XP_006715582
          Length = 2106

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  TYISAC 9
          TYIS+C
Sbjct: 74 TYISSC 79
>NP_005851
          Length = 263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TYISAC 9
           TYIS+C
Sbjct: 217 TYISSC 222
>NP_079452
          Length = 1382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           TTS+ +S C
Sbjct: 298 TTSSLVSLC 306
>NP_076404
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           T  TY+++C
Sbjct: 205 TAVTYVNSC 213
>NP_061897
          Length = 2071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTSTYISAC 9
            TTST  S+C
Sbjct: 1020 TTSTIRSSC 1028
>XP_005260736
          Length = 1033

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           TTS+ +S C
Sbjct: 298 TTSSLVSLC 306
>XP_006723616
          Length = 1223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           TTS+ +S C
Sbjct: 139 TTSSLVSLC 147
>XP_006723615
          Length = 1382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           TTS+ +S C
Sbjct: 298 TTSSLVSLC 306
>XP_005260735
          Length = 1398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           TTS+ +S C
Sbjct: 314 TTSSLVSLC 322
>XP_005264436
          Length = 1881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTSTYISAC 9
            TTST  S+C
Sbjct: 1020 TTSTIRSSC 1028
>XP_006712098
          Length = 2059

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTSTYISAC 9
            TTST  S+C
Sbjct: 1008 TTSTIRSSC 1016
>XP_006712097
          Length = 2070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TTSTYISAC 9
            TTST  S+C
Sbjct: 1020 TTSTIRSSC 1028
>NP_000126
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   STYISAC 9
           STY  AC
Sbjct: 619 STYCQAC 625
>NP_006437
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   TYISAC 9
           TYIS C
Sbjct: 480 TYISPC 485
>NP_001486
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S+YIS C
Sbjct: 179 SSYISIC 185
>NP_001158511
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  STYISAC 9
          S+YIS C
Sbjct: 46 SSYISIC 52
>NP_001158510
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  STYISAC 9
          S+YIS C
Sbjct: 74 SSYISIC 80
>NP_653297
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   STYISAC 9
           S+Y+S+C
Sbjct: 759 SSYLSSC 765
>NP_006791
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S Y++AC
Sbjct: 336 SAYVAAC 342
>NP_001273096
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   STYISAC 9
           STY  AC
Sbjct: 619 STYCQAC 625
>NP_001269103
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S Y++AC
Sbjct: 353 SAYVAAC 359
>NP_001180199
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S Y++AC
Sbjct: 490 SAYVAAC 496
>NP_523353
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S Y++AC
Sbjct: 502 SAYVAAC 508
>NP_006353
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   STYISA 8
           STYISA
Sbjct: 335 STYISA 340
>XP_005274497
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S Y++AC
Sbjct: 336 SAYVAAC 342
>XP_006724524
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S Y++AC
Sbjct: 353 SAYVAAC 359
>XP_005256351
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   STYISAC 9
           STY  AC
Sbjct: 619 STYCQAC 625
>XP_006721231
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   STYISAC 9
           STY  AC
Sbjct: 278 STYCQAC 284
>XP_006721230
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   STYISAC 9
           STY  AC
Sbjct: 619 STYCQAC 625
>XP_006718483
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   STYISA 8
           STYISA
Sbjct: 335 STYISA 340
>XP_006718482
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   STYISA 8
           STYISA
Sbjct: 335 STYISA 340
>XP_006718481
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   STYISA 8
           STYISA
Sbjct: 335 STYISA 340
>XP_006716390
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S+YIS C
Sbjct: 179 SSYISIC 185
>XP_005273532
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  STYISAC 9
          S+YIS C
Sbjct: 60 SSYISIC 66
>XP_005273531
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  STYISAC 9
          S+YIS C
Sbjct: 88 SSYISIC 94
>XP_005273530
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S+YIS C
Sbjct: 179 SSYISIC 185
>XP_006716389
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S+YIS C
Sbjct: 179 SSYISIC 185
>XP_005273529
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   STYISAC 9
           S+YIS C
Sbjct: 193 SSYISIC 199
>XP_006711224
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   STYISAC 9
           S+Y+S+C
Sbjct: 759 SSYLSSC 765
>XP_006711222
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   STYISAC 9
           S+Y+S+C
Sbjct: 717 SSYLSSC 723
>XP_006711221
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   STYISAC 9
           S+Y+S+C
Sbjct: 759 SSYLSSC 765
>XP_006711220
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   STYISAC 9
           S+Y+S+C
Sbjct: 759 SSYLSSC 765
>NP_941965
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           T+S+Y  AC
Sbjct: 180 TSSSYQQAC 188
>NP_940857
          Length = 5147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   TTSTYISAC 9
           T ++Y+ AC
Sbjct: 442 TFASYVQAC 450
>NP_001443
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   STYISAC 9
           STY+++C
Sbjct: 282 STYMASC 288
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.111    0.332 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 469,936
Number of extensions: 992
Number of successful extensions: 66
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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