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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_031392                                                              16    5631
NP_001007268                                                           16    5631
NP_001182570                                                           16    5631
XP_005246450                                                           16    5631
XP_005246449                                                           16    5631
NP_056127                                                              16    7355
XP_006714407                                                           16    7355
XP_006714405                                                           16    7355
XP_005263349                                                           16    7355
XP_005263348                                                           16    7355
XP_005263347                                                           16    7355
XP_005263346                                                           16    7355
XP_005263345                                                           16    7355
XP_005263344                                                           16    7355
XP_005263343                                                           16    7355
XP_005263342                                                           16    7355
XP_005263341                                                           16    7355
XP_005263340                                                           16    7355
XP_005263339                                                           16    7355
NP_001028738                                                           15    9605
NP_653227                                                              15    9605
NP_001275683                                                           15    9605
NP_001028740                                                           15    9605
NP_071928                                                              15    9605
NP_060777                                                              15    9605
XP_006722033                                                           15    9605
XP_006722032                                                           15    9605
XP_006722031                                                           15    9605
XP_005258053                                                           15    9605
XP_006714549                                                           15    9605
XP_006714548                                                           15    9605
XP_005248392                                                           15    9605
XP_005248393                                                           15    9605
XP_005248391                                                           15    9605
XP_005248390                                                           15    9605
XP_005270524                                                           15    9605
XP_005270523                                                           15    9605

>NP_031392
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TSLISSLV 9
           TSLISS+V
Sbjct: 562 TSLISSVV 569



>NP_001007268
          Length = 1324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TSLISSLV 9
           TSLISS+V
Sbjct: 562 TSLISSVV 569



>NP_001182570
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TSLISSLV 9
           TSLISS+V
Sbjct: 562 TSLISSVV 569



>XP_005246450
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TSLISSLV 9
           TSLISS+V
Sbjct: 562 TSLISSVV 569



>XP_005246449
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TSLISSLV 9
           TSLISS+V
Sbjct: 562 TSLISSVV 569



>NP_056127
          Length = 5005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4025 TTSLVSS 4031



>XP_006714407
          Length = 5004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4024 TTSLVSS 4030



>XP_006714405
          Length = 4103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 3123 TTSLVSS 3129



>XP_005263349
          Length = 4410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 3430 TTSLVSS 3436



>XP_005263348
          Length = 4443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 3463 TTSLVSS 3469



>XP_005263347
          Length = 4640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4046 TTSLVSS 4052



>XP_005263346
          Length = 4983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4003 TTSLVSS 4009



>XP_005263345
          Length = 4991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4011 TTSLVSS 4017



>XP_005263344
          Length = 5005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4025 TTSLVSS 4031



>XP_005263343
          Length = 5009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4029 TTSLVSS 4035



>XP_005263342
          Length = 5025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4045 TTSLVSS 4051



>XP_005263341
          Length = 5026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4046 TTSLVSS 4052



>XP_005263340
          Length = 5026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4046 TTSLVSS 4052



>XP_005263339
          Length = 5026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    TTSLISS 7
            TTSL+SS
Sbjct: 4046 TTSLVSS 4052



>NP_001028738
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>NP_653227
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSLISSLV 9
           TTS I+SL+
Sbjct: 211 TTSSIASLI 219



>NP_001275683
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>NP_001028740
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>NP_071928
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>NP_060777
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>XP_006722033
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>XP_006722032
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>XP_006722031
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>XP_005258053
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSLISSLV 9
          TSLI SLV
Sbjct: 18 TSLIMSLV 25



>XP_006714549
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>XP_006714548
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>XP_005248392
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>XP_005248393
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>XP_005248391
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>XP_005248390
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TTSLISSL 8
          T SLISSL
Sbjct: 17 TESLISSL 24



>XP_005270524
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSLISSLV 9
           TTS I+SL+
Sbjct: 211 TTSSIASLI 219



>XP_005270523
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSLISSLV 9
           TTS I+SL+
Sbjct: 211 TTSSIASLI 219



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.115    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 263,193
Number of extensions: 380
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)