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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     869
XP_006716142                                                           19     869
XP_005250088                                                           19     869
XP_006716141                                                           19     869
XP_005250085                                                           19     869
XP_006716140                                                           19     869
XP_005250084                                                           19     869
XP_005250083                                                           19     869
XP_005250082                                                           19     869
NP_055838                                                              17    2528
NP_001263181                                                           17    2528
NP_001124396                                                           17    4312
NP_001010866                                                           17    4312
XP_006710481                                                           17    4312
XP_006710480                                                           17    4312
NP_689777                                                              16    5631
NP_060360                                                              16    5631
XP_005250858                                                           16    5631
XP_005250857                                                           16    5631
NP_777558                                                              16    7355
XP_005263928                                                           16    7355
XP_005263926                                                           16    7355
XP_005263927                                                           16    7355
XP_005251896                                                           15    9605
XP_005251895                                                           15    9605
XP_005251894                                                           15    9605
NP_055925                                                              15    9605

>NP_733751
          Length = 4911

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1672 TTRVKQIA 1679



>XP_006716142
          Length = 4927

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>XP_005250088
          Length = 4928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>XP_006716141
          Length = 4959

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>XP_005250085
          Length = 4979

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>XP_006716140
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>XP_005250084
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>XP_005250083
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1688 TTRVKQIA 1695



>XP_005250082
          Length = 4983

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TTRVKQIA 8
            TTRVKQIA
Sbjct: 1689 TTRVKQIA 1696



>NP_055838
          Length = 676

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTRVKQIAT 9
           T RVK+IAT
Sbjct: 134 TNRVKRIAT 142



>NP_001263181
          Length = 677

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TTRVKQIAT 9
           T RVK+IAT
Sbjct: 134 TNRVKRIAT 142



>NP_001124396
          Length = 666

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTRVKQIA 8
           TT++KQ+A
Sbjct: 129 TTKIKQLA 136



>NP_001010866
          Length = 392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTRVKQIA 8
           TT++KQ+A
Sbjct: 129 TTKIKQLA 136



>XP_006710481
          Length = 542

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTRVKQIA 8
           TT++KQ+A
Sbjct: 129 TTKIKQLA 136



>XP_006710480
          Length = 642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTRVKQIA 8
           TT++KQ+A
Sbjct: 129 TTKIKQLA 136



>NP_689777
          Length = 3997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TTRVKQIAT 9
            T+ +KQIAT
Sbjct: 2888 TSLIKQIAT 2896



>NP_060360
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TTRVKQIAT 9
            T+ +KQIAT
Sbjct: 2913 TSLIKQIAT 2921



>XP_005250858
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TTRVKQIAT 9
            T+ +KQIAT
Sbjct: 2913 TSLIKQIAT 2921



>XP_005250857
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TTRVKQIAT 9
            T+ +KQIAT
Sbjct: 2913 TSLIKQIAT 2921



>NP_777558
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TTRVKQI 7
           TTR+K+I
Sbjct: 135 TTRIKEI 141



>XP_005263928
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TTRVKQI 7
           TTR+K+I
Sbjct: 135 TTRIKEI 141



>XP_005263926
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TTRVKQI 7
           TTR+K+I
Sbjct: 135 TTRIKEI 141



>XP_005263927
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TTRVKQI 7
           TTR+K+I
Sbjct: 135 TTRIKEI 141



>XP_005251896
          Length = 1063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRVKQIAT 9
           TR+KQI T
Sbjct: 569 TRLKQIYT 576



>XP_005251895
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRVKQIAT 9
           TR+KQI T
Sbjct: 583 TRLKQIYT 590



>XP_005251894
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRVKQIAT 9
           TR+KQI T
Sbjct: 607 TRLKQIYT 614



>NP_055925
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRVKQIAT 9
           TR+KQI T
Sbjct: 607 TRLKQIYT 614



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.116    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 287,579
Number of extensions: 259
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)