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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1135
NP_001138390                                                           18    1135
NP_001138386                                                           18    1135
NP_001138387                                                           18    1135
NP_000132                                                              18    1135
NP_075259                                                              18    1135
NP_001138388                                                           18    1135
NP_001138391                                                           18    1135
NP_001138385                                                           18    1135
NP_075418                                                              18    1135
XP_006717776                                                           18    1135
XP_006717775                                                           18    1135
XP_006717774                                                           18    1135
XP_006717773                                                           18    1135
XP_006717772                                                           18    1135
XP_006717771                                                           18    1135
NP_000312                                                              16    5631

>NP_001138389
          Length = 705

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 332 TTRLSSTA 339



>NP_001138390
          Length = 704

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 331 TTRLSSTA 338



>NP_001138386
          Length = 709

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 336 TTRLSSTA 343



>NP_001138387
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 359 TTRLSSTA 366



>NP_000132
          Length = 821

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 448 TTRLSSTA 455



>NP_075259
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 449 TTRLSSTA 456



>NP_001138388
          Length = 706

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 333 TTRLSSTA 340



>NP_001138391
          Length = 680

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 360 TTRLSSTA 367



>NP_001138385
          Length = 769

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 449 TTRLSSTA 456



>NP_075418
          Length = 732

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 359 TTRLSSTA 366



>XP_006717776
          Length = 806

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 467 TTRLSSTA 474



>XP_006717775
          Length = 726

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 353 TTRLSSTA 360



>XP_006717774
          Length = 752

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 379 TTRLSSTA 386



>XP_006717773
          Length = 807

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 468 TTRLSSTA 475



>XP_006717772
          Length = 838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 465 TTRLSSTA 472



>XP_006717771
          Length = 839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTRLSSTA
Sbjct: 466 TTRLSSTA 473



>NP_000312
          Length = 928

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TTRLSSTA 8
           TTR++STA
Sbjct: 619 TTRVNSTA 626



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.106    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 265,265
Number of extensions: 323
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)