Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_031392                                                              16    5631
NP_001007268                                                           16    5631
NP_001182570                                                           16    5631
XP_005246450                                                           16    5631
XP_005246449                                                           16    5631
NP_001028738                                                           16    7355
NP_001275683                                                           16    7355
NP_001028740                                                           16    7355
NP_060777                                                              16    7355
XP_006722033                                                           16    7355
XP_006722032                                                           16    7355
XP_006722031                                                           16    7355
XP_005258053                                                           16    7355
NP_006725                                                              15    9605
XP_005267014                                                           15    9605
>NP_031392
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TSLISSLV 8
           TSLISS+V
Sbjct: 562 TSLISSVV 569
>NP_001007268
          Length = 1324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TSLISSLV 8
           TSLISS+V
Sbjct: 562 TSLISSVV 569
>NP_001182570
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TSLISSLV 8
           TSLISS+V
Sbjct: 562 TSLISSVV 569
>XP_005246450
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TSLISSLV 8
           TSLISS+V
Sbjct: 562 TSLISSVV 569
>XP_005246449
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TSLISSLV 8
           TSLISS+V
Sbjct: 562 TSLISSVV 569
>NP_001028738
          Length = 659

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>NP_001275683
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>NP_001028740
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>NP_060777
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>XP_006722033
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>XP_006722032
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>XP_006722031
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>XP_005258053
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TSLISSLVT 9
          TSLI SLV+
Sbjct: 18 TSLIMSLVS 26
>NP_006725
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TSLISSLVT 9
            +SLIS LVT
Sbjct: 1966 SSLISYLVT 1974
>XP_005267014
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TSLISSLVT 9
            +SLIS LVT
Sbjct: 1966 SSLISYLVT 1974
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.115    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 253,498
Number of extensions: 316
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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