Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001136098                                                           20     390
NP_000360                                                              20     390
NP_001018046                                                           20     390
XP_005268096                                                           20     390
XP_006720308                                                           20     390
XP_005268094                                                           20     390
NP_945119                                                              17    4312
NP_056235                                                              17    4312
NP_064595                                                              17    4312
XP_005254887                                                           17    4312
NP_001166896                                                           16    7355
NP_056219                                                              16    7355
NP_005088                                                              16    7355
NP_065433                                                              16    7355
NP_001243224                                                           16    7355
NP_005230                                                              16    7355
NP_036423                                                              16    7355
NP_060952                                                              16    7355
NP_001099003                                                           16    7355
NP_001009182                                                           16    7355
NP_071335                                                              16    7355
NP_003607                                                              16    7355
NP_064599                                                              16    7355
NP_001234925                                                           16    7355
XP_005260992                                                           16    7355
XP_005254616                                                           16    7355
XP_005254615                                                           16    7355
XP_005254614                                                           16    7355
XP_006719768                                                           16    7355
XP_006717104                                                           16    7355
XP_005251952                                                           16    7355
XP_006716630                                                           16    7355
XP_006716629                                                           16    7355
XP_006716628                                                           16    7355
XP_006716627                                                           16    7355
XP_006716626                                                           16    7355
XP_005250982                                                           16    7355
NP_570124                                                              15    9605
NP_009167                                                              15    9605
NP_001161842                                                           15    9605
NP_055595                                                              15    9605
NP_060720                                                              15    9605
NP_063944                                                              15    9605
NP_001182408                                                           15    9605
NP_006061                                                              15    9605
NP_001007566                                                           15    9605
NP_001182407                                                           15    9605
NP_116178                                                              15    9605
NP_001166033                                                           15    9605
NP_005984                                                              15    9605
XP_005256462                                                           15    9605
XP_006722355                                                           15    9605
XP_005256461                                                           15    9605
XP_005256460                                                           15    9605
XP_005256459                                                           15    9605
XP_005256457                                                           15    9605
XP_005256458                                                           15    9605
XP_006722354                                                           15    9605
XP_005256456                                                           15    9605
XP_006722353                                                           15    9605
XP_005256453                                                           15    9605
XP_005254197                                                           15    9605
XP_006718376                                                           15    9605
XP_005251138                                                           15    9605
XP_005273625                                                           15    9605
XP_006716420                                                           15    9605
XP_006716419                                                           15    9605
XP_006715913                                                           15    9605
XP_006715348                                                           15    9605
XP_005249560                                                           15    9605
XP_005247123                                                           15    9605
XP_006713536                                                           15    9605
XP_006713535                                                           15    9605
NP_001138631                                                           15    9605
>NP_001136098
          Length = 274

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TSKDIQRIP 9
          T KDIQRIP
Sbjct: 40 TCKDIQRIP 48
>NP_000360
          Length = 764

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TSKDIQRIP 9
          T KDIQRIP
Sbjct: 40 TCKDIQRIP 48
>NP_001018046
          Length = 253

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TSKDIQRIP 9
          T KDIQRIP
Sbjct: 40 TCKDIQRIP 48
>XP_005268096
          Length = 253

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TSKDIQRIP 9
          T KDIQRIP
Sbjct: 40 TCKDIQRIP 48
>XP_006720308
          Length = 274

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TSKDIQRIP 9
          T KDIQRIP
Sbjct: 40 TCKDIQRIP 48
>XP_005268094
          Length = 764

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TSKDIQRIP 9
          T KDIQRIP
Sbjct: 40 TCKDIQRIP 48
>NP_945119
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TSKDIQRI 8
           T KD+QR+
Sbjct: 362 TMKDVQRV 369
>NP_056235
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TSKDIQRIP 9
           T  D+QR+P
Sbjct: 169 TKLDLQRVP 177
>NP_064595
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TSKDIQRI 8
           T KD+QR+
Sbjct: 362 TMKDVQRV 369
>XP_005254887
          Length = 977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TSKDIQRI 8
           T KD+QR+
Sbjct: 502 TMKDVQRV 509
>NP_001166896
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TSKDIQRIP 9
           T KD+ R+P
Sbjct: 355 TVKDVGRLP 363
>NP_056219
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TSKDIQRIP 9
           T KD+ R+P
Sbjct: 355 TVKDVGRLP 363
>NP_005088
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +DIQR+P
Sbjct: 466 QDIQRMP 472
>NP_065433
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           S+DIQRI
Sbjct: 573 SEDIQRI 579
>NP_001243224
          Length = 609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   DIQRIP 9
           D+QR+P
Sbjct: 444 DVQRVP 449
>NP_005230
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   DIQRIP 9
           D+QR+P
Sbjct: 304 DVQRVP 309
>NP_036423
          Length = 2120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KDIQRIP 9
            KD+Q++P
Sbjct: 1897 KDLQKLP 1903
>NP_060952
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 443 EDVQRLP 449
>NP_001099003
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   DIQRIP 9
           D+QR+P
Sbjct: 774 DVQRVP 779
>NP_001009182
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SKDIQRIP 9
           SKD +R+P
Sbjct: 235 SKDDERVP 242
>NP_071335
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIQRIP 9
           DIQR+P
Sbjct: 222 DIQRLP 227
>NP_003607
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SKDIQRIP 9
           SKD +R+P
Sbjct: 250 SKDDERVP 257
>NP_064599
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TSKDIQR 7
           TSKD+Q+
Sbjct: 571 TSKDLQK 577
>NP_001234925
          Length = 1122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 436 EDVQRLP 442
>XP_005260992
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   DIQRIP 9
           D+QR+P
Sbjct: 304 DVQRVP 309
>XP_005254616
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TSKDIQR 7
           TSKD+Q+
Sbjct: 551 TSKDLQK 557
>XP_005254615
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TSKDIQR 7
           TSKD+Q+
Sbjct: 552 TSKDLQK 558
>XP_005254614
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TSKDIQR 7
           TSKD+Q+
Sbjct: 572 TSKDLQK 578
>XP_006719768
          Length = 2120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    KDIQRIP 9
            KD+Q++P
Sbjct: 1897 KDLQKLP 1903
>XP_006717104
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TSKDIQRIP 9
           T KD+ R+P
Sbjct: 355 TVKDVGRLP 363
>XP_005251952
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TSKDIQRIP 9
           T KD+ R+P
Sbjct: 355 TVKDVGRLP 363
>XP_006716630
          Length = 1073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 387 EDVQRLP 393
>XP_006716629
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 446 EDVQRLP 452
>XP_006716628
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 390 EDVQRLP 396
>XP_006716627
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 439 EDVQRLP 445
>XP_006716626
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 446 EDVQRLP 452
>XP_005250982
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 446 EDVQRLP 452
>NP_570124
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSKDIQRI 8
           TSKD Q+I
Sbjct: 319 TSKDQQKI 326
>NP_009167
          Length = 195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  KDIQRIP 9
          +D QRIP
Sbjct: 49 EDFQRIP 55
>NP_001161842
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TSKDIQR 7
            TSK++QR
Sbjct: 1394 TSKELQR 1400
>NP_055595
          Length = 1698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TSKDIQR 7
            TSK++QR
Sbjct: 1310 TSKELQR 1316
>NP_060720
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>NP_063944
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TSKDIQRIP 9
           + K+IQ++P
Sbjct: 416 SEKEIQKLP 424
>NP_001182408
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>NP_006061
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>NP_001007566
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>NP_001182407
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>NP_116178
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 205 EDLQRLP 211
>NP_001166033
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           +KDIQR+
Sbjct: 134 NKDIQRL 140
>NP_005984
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SKDIQRI 8
            SKDIQ++
Sbjct: 1082 SKDIQKL 1088
>XP_005256462
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_006722355
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256461
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256460
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256459
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256457
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256458
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_006722354
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 650 SKDIQKL 656
>XP_005256456
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           SKDIQ++
Sbjct: 654 SKDIQKL 660
>XP_006722353
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SKDIQRI 8
            SKDIQ++
Sbjct: 1055 SKDIQKL 1061
>XP_005256453
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SKDIQRI 8
            SKDIQ++
Sbjct: 1065 SKDIQKL 1071
>XP_005254197
          Length = 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  KDIQRIP 9
          +D QRIP
Sbjct: 49 EDFQRIP 55
>XP_006718376
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SKDIQRIP 9
           S+D++R+P
Sbjct: 260 SEDLRRLP 267
>XP_005251138
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KDIQRIP 9
           +D+QR+P
Sbjct: 217 EDLQRLP 223
>XP_005273625
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>XP_006716420
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>XP_006716419
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>XP_006715913
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSKDIQRI 8
           TSKD Q+I
Sbjct: 111 TSKDQQKI 118
>XP_006715348
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TSKDIQR 7
            TSK++QR
Sbjct: 1342 TSKELQR 1348
>XP_005249560
          Length = 1750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TSKDIQR 7
            TSK++QR
Sbjct: 1362 TSKELQR 1368
>XP_005247123
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>XP_006713536
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>XP_006713535
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KDIQRIP 9
          +DI+RIP
Sbjct: 19 EDIRRIP 25
>NP_001138631
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKDIQRI 8
           +KDIQR+
Sbjct: 137 NKDIQRL 143
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.132    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 554,623
Number of extensions: 1113
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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