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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           18    1482
NP_004439                                                              18    1482
NP_001276865                                                           18    1482
NP_001005862                                                           18    1482
XP_005257197                                                           18    1482
XP_006721828                                                           18    1482
NP_005679                                                              16    7355
XP_005247116                                                           16    7355
XP_005247115                                                           16    7355
NP_666018                                                              15    9605
NP_001013660                                                           15    9605
NP_115960                                                              15    9605
NP_001276087                                                           15    9605
NP_001003760                                                           15    9605
XP_005260175                                                           15    9605
XP_005249164                                                           15    9605
XP_006713469                                                           15    9605
NP_001276088                                                           15    9605

>NP_001276866
          Length = 1055

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TSIISA VG
Sbjct: 652 TSIISAVVG 660



>NP_004439
          Length = 1255

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TSIISA VG
Sbjct: 652 TSIISAVVG 660



>NP_001276865
          Length = 1240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TSIISA VG
Sbjct: 637 TSIISAVVG 645



>NP_001005862
          Length = 1225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TSIISA VG
Sbjct: 622 TSIISAVVG 630



>XP_005257197
          Length = 1225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TSIISA VG
Sbjct: 622 TSIISAVVG 630



>XP_006721828
          Length = 1336

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TSIISA VG
Sbjct: 733 TSIISAVVG 741



>NP_005679
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TS+ISA +G
Sbjct: 602 TSLISAILG 610



>XP_005247116
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TS+ISA +G
Sbjct: 602 TSLISAILG 610



>XP_005247115
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           TS+ISA +G
Sbjct: 602 TSLISAILG 610



>NP_666018
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IISAAVG 9
          +ISAA+G
Sbjct: 23 VISAAIG 29



>NP_001013660
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSIISAAV 8
           TS+ISA V
Sbjct: 319 TSVISAGV 326



>NP_115960
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           + ++SAA+G
Sbjct: 267 SQVVSAAIG 275



>NP_001276087
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           + ++SAA+G
Sbjct: 215 SQVVSAAIG 223



>NP_001003760
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SIISAAV 8
           SIISAAV
Sbjct: 142 SIISAAV 148



>XP_005260175
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           + ++SAA+G
Sbjct: 267 SQVVSAAIG 275



>XP_005249164
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SIISAAV 8
           SIISAAV
Sbjct: 142 SIISAAV 148



>XP_006713469
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  TSIISAA 7
          TSI+SAA
Sbjct: 33 TSIVSAA 39



>NP_001276088
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TSIISAAVG 9
           + ++SAA+G
Sbjct: 141 SQVVSAAIG 149



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.120    0.280 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 231,570
Number of extensions: 248
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)