Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_997320                                                              17    3301
NP_207837                                                              17    3301
NP_808592                                                              17    3301
NP_004306                                                              17    3301
NP_001120977                                                           17    3301
NP_006411                                                              17    3301
XP_005260309                                                           17    3301
XP_005253612                                                           17    3301
XP_005273561                                                           17    3301
NP_620481                                                              17    3301
NP_055210                                                              17    3301
XP_006726603                                                           17    4312
XP_006725215                                                           17    4312
XP_006719237                                                           17    4312
XP_005248296                                                           17    4312
XP_005248295                                                           17    4312
NP_009208                                                              17    4312
NP_057593                                                              16    5631
NP_001082                                                              16    5631
NP_001259001                                                           16    5631
NP_057069                                                              16    5631
XP_006723630                                                           16    5631
XP_005260777                                                           16    5631
XP_005253439                                                           16    5631
XP_005250024                                                           16    5631
XP_006715981                                                           16    5631
NP_001153059                                                           16    7355
NP_001153060                                                           16    7355
NP_598000                                                              16    7355
NP_006412                                                              16    7355
NP_001127911                                                           16    7355
NP_001127910                                                           16    7355
NP_665696                                                              16    7355
NP_002135                                                              16    7355
NP_005513                                                              16    7355
NP_689634                                                              16    7355
NP_078777                                                              16    7355
XP_006724942                                                           16    7355
XP_006717017                                                           16    7355
XP_006716481                                                           16    7355
XP_005251193                                                           16    7355
XP_005251192                                                           16    7355
XP_005251191                                                           16    7355
XP_005248716                                                           16    7355
XP_005246564                                                           16    7355
XP_006710331                                                           16    7355
NP_689940                                                              16    7355
NP_001127909                                                           16    7355
NP_064445                                                              15    9605
NP_000504                                                              15    9605
NP_001364                                                              15    9605
NP_036419                                                              15    9605
NP_001263215                                                           15    9605
NP_068749                                                              15    9605
NP_001041646                                                           15    9605
XP_005276782                                                           15    9605
XP_003960138                                                           15    9605
XP_005250581                                                           15    9605
XP_006713621                                                           15    9605
XP_006713620                                                           15    9605
XP_006711798                                                           15    9605
>NP_997320
          Length = 4471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    WMIVQR 8
            WM+VQR
Sbjct: 1477 WMLVQR 1482
>NP_207837
          Length = 1308

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   TRWMIVQRN 9
           T W I+Q N
Sbjct: 629 TAWTIIQHN 637
>NP_808592
          Length = 395

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RWMIVQRN 9
           RW +VQ N
Sbjct: 313 RWYVVQTN 320
>NP_004306
          Length = 411

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RWMIVQRN 9
           RW +VQ N
Sbjct: 329 RWYVVQTN 336
>NP_001120977
          Length = 389

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RWMIVQRN 9
           RW +VQ N
Sbjct: 307 RWYVVQTN 314
>NP_006411
          Length = 1785

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           RWM++Q
Sbjct: 496 RWMVIQ 501
>XP_005260309
          Length = 1784

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           RWM++Q
Sbjct: 495 RWMVIQ 500
>XP_005253612
          Length = 4589

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    WMIVQR 8
            WM+VQR
Sbjct: 1595 WMLVQR 1600
>XP_005273561
          Length = 373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RWMIVQRN 9
           RW +VQ N
Sbjct: 291 RWYVVQTN 298
>NP_620481
          Length = 1235

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   TRWMIVQRN 9
           T W I+Q N
Sbjct: 556 TAWTIIQHN 564
>NP_055210
          Length = 280

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   TRWMIVQRN 9
           TRW  + RN
Sbjct: 183 TRWFTLHRN 191
>XP_006726603
          Length = 1264

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  WMIVQRN 9
          W++V+RN
Sbjct: 6  WIVVKRN 12
>XP_006725215
          Length = 1264

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  WMIVQRN 9
          W++V+RN
Sbjct: 6  WIVVKRN 12
>XP_006719237
          Length = 1263

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  WMIVQRN 9
          W++V+RN
Sbjct: 6  WIVVKRN 12
>XP_005248296
          Length = 630

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   WMIVQRN 9
           WM++QR+
Sbjct: 192 WMVLQRS 198
>XP_005248295
          Length = 745

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   WMIVQRN 9
           WM++QR+
Sbjct: 192 WMVLQRS 198
>NP_009208
          Length = 745

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   WMIVQRN 9
           WM++QR+
Sbjct: 192 WMVLQRS 198
>NP_057593
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  WMIVQRN 9
          W ++QRN
Sbjct: 54 WSVMQRN 60
>NP_001082
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   WMIVQR 8
           W+I+QR
Sbjct: 200 WLIIQR 205
>NP_001259001
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   WMIVQR 8
           W+I+QR
Sbjct: 200 WLIIQR 205
>NP_057069
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   RWMIVQR 8
           RW ++QR
Sbjct: 328 RWTLIQR 334
>XP_006723630
          Length = 341

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   RWMIVQR 8
           RW ++QR
Sbjct: 166 RWTLIQR 172
>XP_005260777
          Length = 410

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   RWMIVQR 8
           RW ++QR
Sbjct: 328 RWTLIQR 334
>XP_005253439
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  WMIVQRN 9
          W ++QRN
Sbjct: 54 WSVMQRN 60
>XP_005250024
          Length = 751

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   WMIVQR 8
           W+I+QR
Sbjct: 200 WLIIQR 205
>XP_006715981
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   WMIVQR 8
           W+I+QR
Sbjct: 200 WLIIQR 205
>NP_001153059
          Length = 1428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    RWMIVQRN 9
            RW+  QRN
Sbjct: 1166 RWLSRQRN 1173
>NP_001153060
          Length = 1368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    RWMIVQRN 9
            RW+  QRN
Sbjct: 1089 RWLSRQRN 1096
>NP_598000
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    RWMIVQRN 9
            RW+  QRN
Sbjct: 1166 RWLSRQRN 1173
>NP_006412
          Length = 1849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/6 (50%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           +WM++Q
Sbjct: 545 KWMVIQ 550
>NP_001127911
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2    RWMIVQRN 9
            RW +  RN
Sbjct: 1163 RWFVFDRN 1170
>NP_001127910
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2    RWMIVQRN 9
            RW +  RN
Sbjct: 1163 RWFVFDRN 1170
>NP_665696
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2    RWMIVQRN 9
            RW +  RN
Sbjct: 1120 RWFVFDRN 1127
>NP_002135
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   WMIVQRN 9
           WM V+RN
Sbjct: 182 WMKVKRN 188
>NP_005513
          Length = 335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   WMIVQRN 9
           WM V+RN
Sbjct: 207 WMKVKRN 213
>NP_689634
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   WMIVQRN 9
           W ++QRN
Sbjct: 198 WALLQRN 204
>NP_078777
          Length = 328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   WMIVQRN 9
           WM V+RN
Sbjct: 207 WMKVKRN 213
>XP_006724942
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   WMIVQR 8
           WMI+Q+
Sbjct: 155 WMIIQQ 160
>XP_006717017
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   WMIVQRN 9
           W ++QRN
Sbjct: 201 WALLQRN 207
>XP_006716481
          Length = 1649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/6 (50%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           +WM++Q
Sbjct: 345 KWMVIQ 350
>XP_005251193
          Length = 1800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/6 (50%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           +WM++Q
Sbjct: 545 KWMVIQ 550
>XP_005251192
          Length = 1843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/6 (50%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           +WM++Q
Sbjct: 545 KWMVIQ 550
>XP_005251191
          Length = 1849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/6 (50%), Positives = 6/6 (100%)

Query: 2   RWMIVQ 7
           +WM++Q
Sbjct: 545 KWMVIQ 550
>XP_005248716
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    RWMIVQRN 9
            RW+  QRN
Sbjct: 1166 RWLSRQRN 1173
>XP_005246564
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   WMIVQRN 9
           WM V+RN
Sbjct: 207 WMKVKRN 213
>XP_006710331
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   WMIVQR 8
           WMI+Q+
Sbjct: 155 WMIIQQ 160
>NP_689940
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   RWMIVQR 8
           +WM+V R
Sbjct: 189 KWMLVHR 195
>NP_001127909
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2    RWMIVQRN 9
            RW +  RN
Sbjct: 1147 RWFVFDRN 1154
>NP_064445
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 2   RWMIV 6
           RWM+V
Sbjct: 151 RWMVV 155
>NP_000504
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 2   RWMIV 6
           RWM+V
Sbjct: 151 RWMVV 155
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3    WMIVQRN 9
            WM  QRN
Sbjct: 1211 WMNCQRN 1217
>NP_036419
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2   RWMIVQRN 9
           RW  +Q N
Sbjct: 287 RWFSIQNN 294
>NP_001263215
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   WMIVQRN 9
           WM  QRN
Sbjct: 514 WMTNQRN 520
>NP_068749
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   RWMIVQR 8
           RW+ V+R
Sbjct: 437 RWLTVER 443
>NP_001041646
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 2   RWMIV 6
           RWM+V
Sbjct: 151 RWMVV 155
>XP_005276782
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 2   RWMIV 6
           RWM+V
Sbjct: 151 RWMVV 155
>XP_003960138
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 2   RWMIV 6
           RWM+V
Sbjct: 151 RWMVV 155
>XP_005250581
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   RWMIVQR 8
           RW+ V+R
Sbjct: 96  RWLTVER 102
>XP_006713621
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2   RWMIVQRN 9
           RW  +Q N
Sbjct: 294 RWFSIQNN 301
>XP_006713620
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2   RWMIVQRN 9
           RW  +Q N
Sbjct: 294 RWFSIQNN 301
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3    WMIVQRN 9
            WM  QRN
Sbjct: 1211 WMNCQRN 1217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.130    0.490 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 618,907
Number of extensions: 1000
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package