Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           17    2528
NP_001138390                                                           17    2528
NP_001138386                                                           17    2528
NP_001138387                                                           17    2528
NP_000132                                                              17    2528
NP_075259                                                              17    2528
NP_001138388                                                           17    2528
NP_001138391                                                           17    2528
NP_001138385                                                           17    2528
NP_075418                                                              17    2528
XP_006717776                                                           17    2528
XP_006717775                                                           17    2528
XP_006717774                                                           17    2528
XP_006717773                                                           17    2528
XP_006717772                                                           17    2528
XP_006717771                                                           17    2528
NP_001273755                                                           16    7355
NP_056498                                                              16    7355
NP_001157570                                                           15    9605
NP_004376                                                              15    9605
NP_055792                                                              15    9605
NP_001158287                                                           15    9605
NP_001158286                                                           15    9605
XP_006720144                                                           15    9605
XP_005267473                                                           15    9605
XP_005267472                                                           15    9605
XP_005245194                                                           15    9605
NP_001131141                                                           15    9605
>NP_001138389
          Length = 705

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 333 TRLSSTADT 341
>NP_001138390
          Length = 704

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 332 TRLSSTADT 340
>NP_001138386
          Length = 709

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 337 TRLSSTADT 345
>NP_001138387
          Length = 707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 360 TRLSSTADT 368
>NP_000132
          Length = 821

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 449 TRLSSTADT 457
>NP_075259
          Length = 822

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 450 TRLSSTADT 458
>NP_001138388
          Length = 706

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 334 TRLSSTADT 342
>NP_001138391
          Length = 680

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 361 TRLSSTADT 369
>NP_001138385
          Length = 769

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 450 TRLSSTADT 458
>NP_075418
          Length = 732

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 360 TRLSSTADT 368
>XP_006717776
          Length = 806

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 468 TRLSSTADT 476
>XP_006717775
          Length = 726

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 354 TRLSSTADT 362
>XP_006717774
          Length = 752

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 380 TRLSSTADT 388
>XP_006717773
          Length = 807

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 469 TRLSSTADT 477
>XP_006717772
          Length = 838

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 466 TRLSSTADT 474
>XP_006717771
          Length = 839

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           TRLSSTA T
Sbjct: 467 TRLSSTADT 475
>NP_001273755
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SSTAYT 9
          SSTAYT
Sbjct: 67 SSTAYT 72
>NP_056498
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SSTAYT 9
          SSTAYT
Sbjct: 67 SSTAYT 72
>NP_001157570
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LSSTAYT 9
            LSSTA+T
Sbjct: 1049 LSSTAWT 1055
>NP_004376
          Length = 3396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LSSTAYT 9
            LSSTA+T
Sbjct: 1049 LSSTAWT 1055
>NP_055792
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           +R SST+YT
Sbjct: 661 SRDSSTSYT 669
>NP_001158287
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           +R SST+YT
Sbjct: 621 SRDSSTSYT 629
>NP_001158286
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           +R SST+YT
Sbjct: 661 SRDSSTSYT 669
>XP_006720144
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           +R SST+YT
Sbjct: 661 SRDSSTSYT 669
>XP_005267473
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           +R SST+YT
Sbjct: 661 SRDSSTSYT 669
>XP_005267472
          Length = 1340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TRLSSTAYT 9
           +R SST+YT
Sbjct: 661 SRDSSTSYT 669
>XP_005245194
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TRLSSTAYT 9
           TRL S  YT
Sbjct: 252 TRLYSVCYT 260
>NP_001131141
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TRLSSTAYT 9
           TRL S  YT
Sbjct: 217 TRLYSVCYT 225
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.106    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 304,652
Number of extensions: 322
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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