Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_001165783                                                           17    3301
NP_002661                                                              17    3301
NP_001138791                                                           17    3301
XP_006713725                                                           17    3301
XP_006713724                                                           17    3301
XP_006713723                                                           17    3301
NP_001265367                                                           16    5631
NP_001073141                                                           16    5631
NP_056023                                                              16    5631
NP_001190985                                                           16    5631
NP_001077094                                                           16    5631
NP_078964                                                              16    5631
NP_597719                                                              16    5631
NP_001275511                                                           16    5631
XP_006722380                                                           16    5631
XP_005258153                                                           16    5631
XP_005258152                                                           16    5631
XP_005258151                                                           16    5631
XP_005258150                                                           16    5631
XP_005258149                                                           16    5631
XP_006719840                                                           16    5631
XP_005252650                                                           16    5631
XP_006717569                                                           16    5631
XP_006717568                                                           16    5631
XP_006717567                                                           16    5631
XP_006713569                                                           16    5631
NP_066267                                                              16    7355
NP_001155000                                                           16    7355
NP_001005191                                                           16    7355
NP_059129                                                              16    7355
XP_006717852                                                           16    7355
XP_006717851                                                           16    7355
XP_006717850                                                           16    7355
XP_006717849                                                           16    7355
XP_006717848                                                           16    7355
XP_006717847                                                           16    7355
XP_006717846                                                           16    7355
XP_006717845                                                           16    7355
NP_000072                                                              15    9605
NP_003391                                                              15    9605
NP_001231611                                                           15    9605
NP_055167                                                              15    9605
XP_006719964                                                           15    9605
XP_006719963                                                           15    9605
XP_006719962                                                           15    9605
XP_006719961                                                           15    9605
XP_006719960                                                           15    9605
XP_005266656                                                           15    9605
XP_006712159                                                           15    9605
XP_006712158                                                           15    9605
XP_005264603                                                           15    9605
XP_005264601                                                           15    9605
XP_006712157                                                           15    9605
XP_006711794                                                           15    9605
XP_005273086                                                           15    9605
XP_005273085                                                           15    9605
XP_005273084                                                           15    9605
NP_004285                                                              15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TQIKSKDIS 9
            TQIKS+DIS
Sbjct: 2291 TQIKSRDIS 2299
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TQIKSKDIS 9
            TQIKS+DIS
Sbjct: 2086 TQIKSRDIS 2094
>NP_001165783
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          ++KSKDIS
Sbjct: 82 ELKSKDIS 89
>NP_002661
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          ++KSKDIS
Sbjct: 82 ELKSKDIS 89
>NP_001138791
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          ++KSKDIS
Sbjct: 82 ELKSKDIS 89
>XP_006713725
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          ++KSKDIS
Sbjct: 82 ELKSKDIS 89
>XP_006713724
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          ++KSKDIS
Sbjct: 82 ELKSKDIS 89
>XP_006713723
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          ++KSKDIS
Sbjct: 82 ELKSKDIS 89
>NP_001265367
          Length = 1198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TQIKSKDIS 9
          TQI S DIS
Sbjct: 11 TQILSSDIS 19
>NP_001073141
          Length = 1198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TQIKSKDIS 9
          TQI S DIS
Sbjct: 11 TQILSSDIS 19
>NP_056023
          Length = 2062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 826 SQIKEKDI 833
>NP_001190985
          Length = 2039

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 803 SQIKEKDI 810
>NP_001077094
          Length = 2039

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 803 SQIKEKDI 810
>NP_078964
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QIKSKDIS 9
           +IK KDIS
Sbjct: 238 EIKKKDIS 245
>NP_597719
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TQIKSKD 7
           TQIK KD
Sbjct: 569 TQIKEKD 575
>NP_001275511
          Length = 653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TQIKSKD 7
           TQIK KD
Sbjct: 569 TQIKEKD 575
>XP_006722380
          Length = 1769

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 533 SQIKEKDI 540
>XP_005258153
          Length = 2037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 801 SQIKEKDI 808
>XP_005258152
          Length = 2060

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 824 SQIKEKDI 831
>XP_005258151
          Length = 2062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 826 SQIKEKDI 833
>XP_005258150
          Length = 2062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 826 SQIKEKDI 833
>XP_005258149
          Length = 2062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           +QIK KDI
Sbjct: 826 SQIKEKDI 833
>XP_006719840
          Length = 1080

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TQIKSKDIS 9
          TQI S DIS
Sbjct: 11 TQILSSDIS 19
>XP_005252650
          Length = 692

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QIKSKDIS 9
           +IK KDIS
Sbjct: 238 EIKKKDIS 245
>XP_006717569
          Length = 1278

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QIKSKDIS 9
           +IK KDIS
Sbjct: 824 EIKKKDIS 831
>XP_006717568
          Length = 1314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QIKSKDIS 9
           +IK KDIS
Sbjct: 860 EIKKKDIS 867
>XP_006717567
          Length = 1385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QIKSKDIS 9
           +IK KDIS
Sbjct: 931 EIKKKDIS 938
>XP_006713569
          Length = 341

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TQIKSKD 7
           TQIK KD
Sbjct: 140 TQIKEKD 146
>NP_066267
          Length = 4377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2726 THAKSKDMS 2734
>NP_001155000
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQIKSKDIS 9
           TQ+K  DIS
Sbjct: 651 TQLKELDIS 659
>NP_001005191
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QIKSKDIS 9
          Q +SKDIS
Sbjct: 86 QARSKDIS 93
>NP_059129
          Length = 1616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           TQI+ KD+
Sbjct: 288 TQIEGKDV 295
>XP_006717852
          Length = 3508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 1857 THAKSKDMS 1865
>XP_006717851
          Length = 3513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 1862 THAKSKDMS 1870
>XP_006717850
          Length = 4364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2713 THAKSKDMS 2721
>XP_006717849
          Length = 4383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2732 THAKSKDMS 2740
>XP_006717848
          Length = 4392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2741 THAKSKDMS 2749
>XP_006717847
          Length = 4395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2744 THAKSKDMS 2752
>XP_006717846
          Length = 4396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2745 THAKSKDMS 2753
>XP_006717845
          Length = 4397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TQIKSKDIS 9
            T  KSKD+S
Sbjct: 2746 THAKSKDMS 2754
>NP_000072
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KSKDIS 9
            KSKDIS
Sbjct: 2879 KSKDIS 2884
>NP_003391
          Length = 1071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           TQ+KSK +
Sbjct: 187 TQVKSKHL 194
>NP_001231611
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          QIK++D+S
Sbjct: 46 QIKTEDLS 53
>NP_055167
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QIKSKDIS 9
          QIK++D+S
Sbjct: 44 QIKTEDLS 51
>XP_006719964
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
>XP_006719963
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
>XP_006719962
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
>XP_006719961
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
>XP_006719960
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
>XP_005266656
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
>XP_006712159
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TQIKSKDI 8
          TQ+KSK +
Sbjct: 20 TQVKSKHL 27
>XP_006712158
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TQIKSKDI 8
          TQ+KSK +
Sbjct: 20 TQVKSKHL 27
>XP_005264603
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TQIKSKDI 8
          TQ+KSK +
Sbjct: 56 TQVKSKHL 63
>XP_005264601
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           TQ+KSK +
Sbjct: 172 TQVKSKHL 179
>XP_006712157
          Length = 1071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TQIKSKDI 8
           TQ+KSK +
Sbjct: 187 TQVKSKHL 194
>XP_006711794
          Length = 3022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KSKDIS 9
            KSKDIS
Sbjct: 2100 KSKDIS 2105
>XP_005273086
          Length = 3264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KSKDIS 9
            KSKDIS
Sbjct: 2879 KSKDIS 2884
>XP_005273085
          Length = 3755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KSKDIS 9
            KSKDIS
Sbjct: 2833 KSKDIS 2838
>XP_005273084
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KSKDIS 9
            KSKDIS
Sbjct: 2879 KSKDIS 2884
>NP_004285
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TQIKSKDIS 9
           +QIK+K+I+
Sbjct: 340 SQIKNKEIA 348
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.115    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,824
Number of extensions: 557
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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