Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
NP_001002811                                                           18    1482
NP_001002812                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
NP_612355                                                              17    3301
NP_001136028                                                           17    3301
NP_036616                                                              17    3301
NP_001136029                                                           17    3301
NP_036617                                                              17    3301
XP_006726657                                                           17    3301
XP_006725285                                                           17    3301
XP_005263588                                                           17    3301
NP_001138344                                                           16    5631
XP_005253936                                                           16    5631
NP_851320                                                              16    7355
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 897 TQEVLLLRE 905
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 831 TQEVLLLRE 839
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 831 TQEVLLLRE 839
>NP_001002811
          Length = 1132

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 831 TQEVLLLRE 839
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 897 TQEVLLLRE 905
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 897 TQEVLLLRE 905
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 897 TQEVLLLRE 905
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 831 TQEVLLLRE 839
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 831 TQEVLLLRE 839
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 834 TQEVLLLRE 842
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 897 TQEVLLLRE 905
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ VLLLRE
Sbjct: 897 TQEVLLLRE 905
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TQAVLLLRE 9
            TQ VLLLRE
Sbjct: 994  TQEVLLLRE 1002
>NP_612355
          Length = 634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   QAVLLLRE 9
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>NP_001136028
          Length = 725

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQA LLL+E
Sbjct: 436 TQATLLLQE 444
>NP_036616
          Length = 724

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQA LLL+E
Sbjct: 435 TQATLLLQE 443
>NP_001136029
          Length = 638

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQA LLL+E
Sbjct: 349 TQATLLLQE 357
>NP_036617
          Length = 709

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQA LLL+E
Sbjct: 420 TQATLLLQE 428
>XP_006726657
          Length = 633

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   QAVLLLRE 9
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>XP_006725285
          Length = 633

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   QAVLLLRE 9
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>XP_005263588
          Length = 667

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   QAVLLLRE 9
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>NP_001138344
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TQAVLLLRE 9
           TQA L LRE
Sbjct: 173 TQAALRLRE 181
>XP_005253936
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TQAVLLLRE 9
           TQA L LRE
Sbjct: 173 TQAALRLRE 181
>NP_851320
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TQAVLLLRE 9
           TQ+VLLL E
Sbjct: 297 TQSVLLLWE 305
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.137    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,142
Number of extensions: 403
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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