Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_001623                                                              17    3301
XP_005246496                                                           17    3301
NP_112603                                                              17    3301
NP_001245258                                                           17    4312
NP_001245260                                                           17    4312
NP_001245259                                                           17    4312
NP_818932                                                              17    4312
NP_036288                                                              17    4312
XP_005260382                                                           17    4312
XP_005260381                                                           17    4312
XP_006723804                                                           17    4312
XP_005260380                                                           17    4312
XP_006723803                                                           17    4312
XP_005260379                                                           17    4312
XP_005260378                                                           17    4312
XP_005260377                                                           17    4312
XP_006723802                                                           17    4312
XP_005260376                                                           17    4312
XP_006723801                                                           17    4312
XP_006723800                                                           17    4312
XP_006723799                                                           17    4312
XP_006723798                                                           17    4312
NP_001026850                                                           16    5631
NP_004341                                                              16    5631
NP_078966                                                              16    5631
NP_001230925                                                           16    5631
NP_001185761                                                           16    5631
NP_001027                                                              16    5631
NP_001185763                                                           16    5631
NP_055459                                                              16    5631
NP_001010854                                                           16    5631
XP_006726410                                                           16    5631
XP_005267424                                                           16    5631
XP_006720122                                                           16    5631
XP_006720121                                                           16    5631
XP_006711719                                                           16    5631
XP_006711718                                                           16    5631
XP_006711717                                                           16    5631
XP_006711716                                                           16    5631
XP_006711715                                                           16    5631
XP_006711714                                                           16    5631
XP_006711713                                                           16    5631
XP_006711712                                                           16    5631
XP_006711711                                                           16    5631
XP_006711710                                                           16    5631
XP_006711709                                                           16    5631
XP_005277503                                                           16    5631
XP_005273038                                                           16    5631
XP_006711708                                                           16    5631
XP_005277500                                                           16    5631
XP_006711707                                                           16    5631
XP_005277499                                                           16    5631
XP_006711706                                                           16    5631
XP_006711705                                                           16    5631
XP_006711164                                                           16    5631
XP_005246081                                                           16    5631
XP_006710143                                                           16    5631
XP_006710142                                                           16    5631
XP_006710141                                                           16    5631
NP_543146                                                              16    5631
NP_620063                                                              16    7355
NP_001092805                                                           15    9605
NP_055574                                                              15    9605
NP_851320                                                              15    9605
XP_006716479                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TMSLSTTDH 9
            TMS STTDH
Sbjct: 2130 TMSPSTTDH 2138
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TMSLSTTDH 9
            TMS STTDH
Sbjct: 1925 TMSPSTTDH 1933
>NP_001623
          Length = 535

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+SL T DH
Sbjct: 372 TLSLVTADH 380
>XP_005246496
          Length = 550

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+SL T DH
Sbjct: 387 TLSLVTADH 395
>NP_112603
          Length = 532

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+SL T DH
Sbjct: 369 TLSLVTADH 377
>NP_001245258
          Length = 880

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 801 TLSTSTTTH 809
>NP_001245260
          Length = 779

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 700 TLSTSTTTH 708
>NP_001245259
          Length = 701

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 622 TLSTSTTTH 630
>NP_818932
          Length = 779

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 700 TLSTSTTTH 708
>NP_036288
          Length = 881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 802 TLSTSTTTH 810
>XP_005260382
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 653 TLSTSTTTH 661
>XP_005260381
          Length = 744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 665 TLSTSTTTH 673
>XP_006723804
          Length = 819

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 740 TLSTSTTTH 748
>XP_005260380
          Length = 841

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 762 TLSTSTTTH 770
>XP_006723803
          Length = 853

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 774 TLSTSTTTH 782
>XP_005260379
          Length = 867

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 788 TLSTSTTTH 796
>XP_005260378
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 789 TLSTSTTTH 797
>XP_005260377
          Length = 869

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 790 TLSTSTTTH 798
>XP_006723802
          Length = 880

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 801 TLSTSTTTH 809
>XP_005260376
          Length = 880

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 801 TLSTSTTTH 809
>XP_006723801
          Length = 881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 802 TLSTSTTTH 810
>XP_006723800
          Length = 881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 802 TLSTSTTTH 810
>XP_006723799
          Length = 881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 802 TLSTSTTTH 810
>XP_006723798
          Length = 916

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMSLSTTDH 9
           T+S STT H
Sbjct: 837 TLSTSTTTH 845
>NP_001026850
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLSTT H
Sbjct: 232 SLSTTSH 238
>NP_004341
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLSTT H
Sbjct: 218 SLSTTSH 224
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SLSTTDH 9
            SLSTT H
Sbjct: 7745 SLSTTSH 7751
>NP_001230925
          Length = 4865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    TMSLSTTD 8
            T+SLSTT+
Sbjct: 2401 TVSLSTTE 2408
>NP_001185761
          Length = 2240

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1501 TSKLSTKDH 1509
>NP_001027
          Length = 4870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    TMSLSTTD 8
            T+SLSTT+
Sbjct: 2401 TVSLSTTE 2408
>NP_001185763
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1545 TSKLSTKDH 1553
>NP_055459
          Length = 2346

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1545 TSKLSTKDH 1553
>NP_001010854
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLS TDH
Sbjct: 509 SLSPTDH 515
>XP_006726410
          Length = 2087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1348 TSKLSTKDH 1356
>XP_005267424
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLS TDH
Sbjct: 251 SLSPTDH 257
>XP_006720122
          Length = 820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLS TDH
Sbjct: 415 SLSPTDH 421
>XP_006720121
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLS TDH
Sbjct: 517 SLSPTDH 523
>XP_006711719
          Length = 2302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1501 TSKLSTKDH 1509
>XP_006711718
          Length = 1436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TMSLSTTDH 9
           T  LST DH
Sbjct: 552 TSKLSTKDH 560
>XP_006711717
          Length = 2385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1501 TSKLSTKDH 1509
>XP_006711716
          Length = 2411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1610 TSKLSTKDH 1618
>XP_006711715
          Length = 2428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1544 TSKLSTKDH 1552
>XP_006711714
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1545 TSKLSTKDH 1553
>XP_006711713
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1548 TSKLSTKDH 1556
>XP_006711712
          Length = 2473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_006711711
          Length = 2482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1598 TSKLSTKDH 1606
>XP_006711710
          Length = 2494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1610 TSKLSTKDH 1618
>XP_006711709
          Length = 2495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1611 TSKLSTKDH 1619
>XP_005277503
          Length = 2498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_005273038
          Length = 2509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_006711708
          Length = 2512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_005277500
          Length = 2525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_006711707
          Length = 2553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_005277499
          Length = 2561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_006711706
          Length = 2591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1707 TSKLSTKDH 1715
>XP_006711705
          Length = 2592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1708 TSKLSTKDH 1716
>XP_006711164
          Length = 2087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TMSLSTTDH 9
            T  LST DH
Sbjct: 1348 TSKLSTKDH 1356
>XP_005246081
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSTTDH 9
           SLSTT H
Sbjct: 232 SLSTTSH 238
>XP_006710143
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TMSLSTTDH 9
           T  LST DH
Sbjct: 387 TSKLSTKDH 395
>XP_006710142
          Length = 671

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TMSLSTTDH 9
           T  LST DH
Sbjct: 496 TSKLSTKDH 504
>XP_006710141
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TMSLSTTDH 9
           T  LST DH
Sbjct: 497 TSKLSTKDH 505
>NP_543146
          Length = 1393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TMSLSTTDH 9
          T  LST+DH
Sbjct: 38 TGELSTSDH 46
>NP_620063
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SLSTTDH 9
          SLSTT H
Sbjct: 56 SLSTTHH 62
>NP_001092805
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MSLSTTD 8
           MSLST D
Sbjct: 308 MSLSTAD 314
>NP_055574
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MSLSTTD 8
           MSLST D
Sbjct: 308 MSLSTAD 314
>NP_851320
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TMSLSTTDH 9
           TM+++ T+H
Sbjct: 101 TMTMNQTEH 109
>XP_006716479
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   MSLSTTD 8
           MSLST D
Sbjct: 308 MSLSTAD 314
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.105    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 353,267
Number of extensions: 446
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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