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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055365                                                              18    1135
NP_001258765                                                           17    2528
NP_001156795                                                           17    2528
NP_296375                                                              17    2528
NP_001156794                                                           17    2528
NP_001156793                                                           17    2528
NP_001258764                                                           17    2528
NP_001188                                                              17    4312
NP_060719                                                              16    7355
NP_001258968                                                           16    7355
NP_001011649                                                           16    7355
NP_002411                                                              16    7355
NP_001238953                                                           16    7355
NP_001238949                                                           16    7355
NP_001273409                                                           16    7355
NP_055598                                                              16    7355
NP_001120676                                                           16    7355
NP_001273197                                                           16    7355
NP_001273196                                                           16    7355
NP_001258547                                                           16    7355
NP_955389                                                              16    7355
NP_060077                                                              16    7355
NP_001273408                                                           16    7355
NP_001273198                                                           16    7355
NP_001273199                                                           16    7355
NP_001120678                                                           16    7355
XP_006725628                                                           16    7355
XP_006725627                                                           16    7355
XP_005259070                                                           16    7355
XP_006720851                                                           16    7355
XP_005254865                                                           16    7355
XP_006717248                                                           16    7355
XP_006717247                                                           16    7355
XP_006717246                                                           16    7355
XP_006717245                                                           16    7355
XP_006717244                                                           16    7355
XP_006717243                                                           16    7355
XP_006717242                                                           16    7355
NP_001120677                                                           16    7355
NP_002125                                                              16    7355
NP_733762                                                              15    9605
XP_006713860                                                           15    9605
XP_006713859                                                           15    9605
XP_005247910                                                           15    9605
XP_005247909                                                           15    9605

>NP_055365
          Length = 1032

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLSE
Sbjct: 211 MRLAQLSE 218



>NP_001258765
          Length = 630

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLS+
Sbjct: 199 MRLAQLSQ 206



>NP_001156795
          Length = 618

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLS+
Sbjct: 187 MRLAQLSQ 194



>NP_296375
          Length = 630

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLS+
Sbjct: 199 MRLAQLSQ 206



>NP_001156794
          Length = 649

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLS+
Sbjct: 187 MRLAQLSQ 194



>NP_001156793
          Length = 696

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLS+
Sbjct: 234 MRLAQLSQ 241



>NP_001258764
          Length = 630

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   MRLAQLSE 9
           MRLAQLS+
Sbjct: 199 MRLAQLSQ 206



>NP_001188
          Length = 160

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  RLAQLSE 9
          RLAQLSE
Sbjct: 76 RLAQLSE 82



>NP_060719
          Length = 1893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1842 TMKLLQLSK 1850



>NP_001258968
          Length = 1663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1612 TMKLLQLSK 1620



>NP_001011649
          Length = 1814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1763 TMKLLQLSK 1771



>NP_002411
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    MRLAQLSE 9
            +RLAQL E
Sbjct: 1215 LRLAQLEE 1222



>NP_001238953
          Length = 1625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    MRLAQLSE 9
            +RLAQL E
Sbjct: 1237 LRLAQLEE 1244



>NP_001238949
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    MRLAQLSE 9
            +RLAQL E
Sbjct: 1254 LRLAQLEE 1261



>NP_001273409
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 122 RIAQLSE 128



>NP_055598
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 311 RIAQLSE 317



>NP_001120676
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>NP_001273197
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>NP_001273196
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 82 MRMADLSE 89



>NP_001258547
          Length = 780

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TMRLAQL 7
           T+RLAQL
Sbjct: 703 TLRLAQL 709



>NP_955389
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 311 RIAQLSE 317



>NP_060077
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TMRLAQL 7
           T+RLAQL
Sbjct: 705 TLRLAQL 711



>NP_001273408
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 122 RIAQLSE 128



>NP_001273198
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>NP_001273199
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>NP_001120678
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>XP_006725628
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 311 RIAQLSE 317



>XP_006725627
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 311 RIAQLSE 317



>XP_005259070
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TMRLAQL 7
           T+RLAQL
Sbjct: 704 TLRLAQL 710



>XP_006720851
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 122 RIAQLSE 128



>XP_005254865
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           R+AQLSE
Sbjct: 311 RIAQLSE 317



>XP_006717248
          Length = 1664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1613 TMKLLQLSK 1621



>XP_006717247
          Length = 1670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1613 TMKLLQLSK 1621



>XP_006717246
          Length = 1820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1763 TMKLLQLSK 1771



>XP_006717245
          Length = 1861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1810 TMKLLQLSK 1818



>XP_006717244
          Length = 1867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1810 TMKLLQLSK 1818



>XP_006717243
          Length = 1889

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1832 TMKLLQLSK 1840



>XP_006717242
          Length = 1898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TMRLAQLSE 9
            TM+L QLS+
Sbjct: 1841 TMKLLQLSK 1849



>NP_001120677
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>NP_002125
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MRLAQLSE 9
          MR+A LSE
Sbjct: 28 MRMADLSE 35



>NP_733762
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           +LAQLSE
Sbjct: 97  KLAQLSE 103



>XP_006713860
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           +LAQLSE
Sbjct: 125 KLAQLSE 131



>XP_006713859
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           +LAQLSE
Sbjct: 125 KLAQLSE 131



>XP_005247910
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           +LAQLSE
Sbjct: 97  KLAQLSE 103



>XP_005247909
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLAQLSE 9
           +LAQLSE
Sbjct: 125 KLAQLSE 131



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.119    0.273 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 230,046
Number of extensions: 198
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)