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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              20     509
NP_001087241                                                           20     509
XP_005265799                                                           20     509
XP_005265798                                                           20     509
XP_005265797                                                           20     509
NP_003560                                                              19     869
NP_002658                                                              17    2528
NP_001274152                                                           17    4312
NP_054858                                                              17    4312
NP_852137                                                              16    5631
NP_612419                                                              16    5631
NP_004320                                                              16    7355
NP_694995                                                              16    7355
NP_001186224                                                           16    7355
XP_006723191                                                           16    7355
NP_001489                                                              15    9605
NP_004247                                                              15    9605
NP_001184044                                                           15    9605

>NP_000213
          Length = 976

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MCIIVMIL 9
           MCIIVMIL
Sbjct: 536 MCIIVMIL 543



>NP_001087241
          Length = 972

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MCIIVMIL 9
           MCIIVMIL
Sbjct: 532 MCIIVMIL 539



>XP_005265799
          Length = 973

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MCIIVMIL 9
           MCIIVMIL
Sbjct: 533 MCIIVMIL 540



>XP_005265798
          Length = 976

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MCIIVMIL 9
           MCIIVMIL
Sbjct: 537 MCIIVMIL 544



>XP_005265797
          Length = 977

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   MCIIVMIL 9
           MCIIVMIL
Sbjct: 537 MCIIVMIL 544



>NP_003560
          Length = 261

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TMCIIVMIL 9
           T+CII++IL
Sbjct: 237 TLCIIILIL 245



>NP_002658
          Length = 52

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  MCIIVMIL 9
          +CIIVM+L
Sbjct: 45 ICIIVMLL 52



>NP_001274152
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TMCIIVMIL 9
           ++C+IV IL
Sbjct: 785 SLCVIVFIL 793



>NP_054858
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TMCIIVMIL 9
           ++C+IV IL
Sbjct: 785 SLCVIVFIL 793



>NP_852137
          Length = 142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TMCIIVMIL 9
          T+C ++MIL
Sbjct: 81 TICDLIMIL 89



>NP_612419
          Length = 175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TMCIIVMIL 9
          T+C ++MIL
Sbjct: 81 TICDLIMIL 89



>NP_004320
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MCIIVMIL 9
           +CII MI+
Sbjct: 162 VCIIAMII 169



>NP_694995
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   MCIIVM 7
           MCI+VM
Sbjct: 95  MCILVM 100



>NP_001186224
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   MCIIVM 7
           MCI+VM
Sbjct: 108 MCILVM 113



>XP_006723191
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  MCIIVM 7
          MCI+VM
Sbjct: 86 MCILVM 91



>NP_001489
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMCIIVMIL 9
           T+C IVM L
Sbjct: 271 TICPIVMAL 279



>NP_004247
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   MCIIVMIL 9
           MCII++ +
Sbjct: 403 MCIIIIFI 410



>NP_001184044
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TMCIIVMIL 9
           T+C IVM L
Sbjct: 233 TICPIVMAL 241



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.362    0.157    0.492 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,081
Number of extensions: 392
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.3 bits)
S2: 28 (15.4 bits)