Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              18    1135
NP_001120972                                                           18    1135
XP_006716052                                                           18    1135
XP_006716051                                                           18    1135
NP_001127945                                                           18    1935
NP_001265113                                                           18    1935
NP_055430                                                              18    1935
XP_005255922                                                           18    1935
XP_006721236                                                           18    1935
XP_006721235                                                           18    1935
XP_005255921                                                           18    1935
XP_005255920                                                           18    1935
XP_005255919                                                           18    1935
XP_005255918                                                           18    1935
XP_005255917                                                           18    1935
XP_005255916                                                           18    1935
NP_001822                                                              17    2528
XP_006716347                                                           17    2528
NP_291032                                                              17    3301
NP_001229453                                                           17    3301
NP_001229454                                                           17    3301
NP_006018                                                              17    3301
NP_569082                                                              17    3301
NP_003677                                                              17    3301
XP_005273407                                                           17    3301
XP_006711903                                                           17    3301
NP_036596                                                              16    5631
NP_003743                                                              16    5631
NP_001254503                                                           16    5631
NP_001273407                                                           16    5631
NP_001032897                                                           16    5631
NP_071894                                                              16    5631
NP_001186071                                                           16    5631
NP_001093131                                                           16    5631
NP_001191689                                                           16    5631
XP_005255592                                                           16    5631
XP_006714356                                                           16    5631
XP_006712752                                                           16    5631
NP_000386                                                              16    7355
NP_006368                                                              16    7355
NP_001073890                                                           16    7355
XP_005261399                                                           16    7355
XP_005261397                                                           16    7355
XP_006722755                                                           16    7355
XP_006716779                                                           16    7355
NP_001035808                                                           15    9605
NP_061845                                                              15    9605
NP_003592                                                              15    9605
NP_803876                                                              15    9605
NP_001257321                                                           15    9605
NP_001257320                                                           15    9605
NP_958834                                                              15    9605
NP_001271286                                                           15    9605
NP_001185947                                                           15    9605
NP_001185946                                                           15    9605
NP_079007                                                              15    9605
NP_060161                                                              15    9605
XP_005256206                                                           15    9605
NP_006133                                                              15    9605
>NP_000236
          Length = 1390

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TLVQRSN E
Sbjct: 17 TLVQRSNGE 25
>NP_001120972
          Length = 1408

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TLVQRSN E
Sbjct: 17 TLVQRSNGE 25
>XP_006716052
          Length = 1409

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TLVQRSN E
Sbjct: 36 TLVQRSNGE 44
>XP_006716051
          Length = 1427

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TLVQRSN E
Sbjct: 36 TLVQRSNGE 44
>NP_001127945
          Length = 1113

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 383 LIQRTNEE 390
>NP_001265113
          Length = 1144

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 414 LIQRTNEE 421
>NP_055430
          Length = 1217

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 487 LIQRTNEE 494
>XP_005255922
          Length = 1154

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 424 LIQRTNEE 431
>XP_006721236
          Length = 1214

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 484 LIQRTNEE 491
>XP_006721235
          Length = 1214

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 484 LIQRTNEE 491
>XP_005255921
          Length = 1227

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 497 LIQRTNEE 504
>XP_005255920
          Length = 1229

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QR+NEE
Sbjct: 499 LIQRTNEE 506
>XP_005255919
          Length = 1860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LVQRSNEE 9
            L+QR+NEE
Sbjct: 1292 LIQRTNEE 1299
>XP_005255918
          Length = 1949

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LVQRSNEE 9
            L+QR+NEE
Sbjct: 1219 LIQRTNEE 1226
>XP_005255917
          Length = 1984

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LVQRSNEE 9
            L+QR+NEE
Sbjct: 1292 LIQRTNEE 1299
>XP_005255916
          Length = 2022

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LVQRSNEE 9
            L+QR+NEE
Sbjct: 1292 LIQRTNEE 1299
>NP_001822
          Length = 449

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  TLVQRSNEE 9
          TL++++NEE
Sbjct: 58 TLIEKTNEE 66
>XP_006716347
          Length = 501

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TLVQRSNEE 9
           TL++++NEE
Sbjct: 110 TLIEKTNEE 118
>NP_291032
          Length = 260

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLVQRSN 7
           TL+QRSN
Sbjct: 103 TLIQRSN 109
>NP_001229453
          Length = 260

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLVQRSN 7
           TL+QRSN
Sbjct: 103 TLIQRSN 109
>NP_001229454
          Length = 260

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLVQRSN 7
           TL+QRSN
Sbjct: 103 TLIQRSN 109
>NP_006018
          Length = 846

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 485 TFLQRKNEE 493
>NP_569082
          Length = 846

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 485 TFLQRKNEE 493
>NP_003677
          Length = 803

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 485 TFLQRKNEE 493
>XP_005273407
          Length = 845

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 484 TFLQRKNEE 492
>XP_006711903
          Length = 846

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 485 TFLQRKNEE 493
>NP_036596
          Length = 1013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           T ++RS+EE
Sbjct: 192 TFIERSDEE 200
>NP_003743
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 446 TLVERMDEE 454
>NP_001254503
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 446 TLVERMDEE 454
>NP_001273407
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 436 TLVERMDEE 444
>NP_001032897
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 446 TLVERMDEE 454
>NP_071894
          Length = 212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QRS+EE
Sbjct: 180 LLQRSDEE 187
>NP_001186071
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 446 TLVERMDEE 454
>NP_001093131
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 447 TLVERMDEE 455
>NP_001191689
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           T ++RS+EE
Sbjct: 192 TFIERSDEE 200
>XP_005255592
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           TLV+R +EE
Sbjct: 447 TLVERMDEE 455
>XP_006714356
          Length = 964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           T ++RS+EE
Sbjct: 143 TFIERSDEE 151
>XP_006712752
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVQRSNEE 9
           L+QRS+EE
Sbjct: 158 LLQRSDEE 165
>NP_000386
          Length = 897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TL++R NE+
Sbjct: 60 TLIRRVNED 68
>NP_006368
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LVQRSNEE 9
            L QRSN+E
Sbjct: 1565 LSQRSNDE 1572
>NP_001073890
          Length = 1703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LVQRSNEE 9
            L QRSN+E
Sbjct: 1672 LSQRSNDE 1679
>XP_005261399
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TL++R NE+
Sbjct: 60 TLIRRVNED 68
>XP_005261397
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          TL++R NE+
Sbjct: 60 TLIRRVNED 68
>XP_006722755
          Length = 1722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LVQRSNEE 9
            L QRSN+E
Sbjct: 1691 LSQRSNDE 1698
>XP_006716779
          Length = 2399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LVQRSNEE 9
            L QRSN+E
Sbjct: 2373 LSQRSNDE 2380
>NP_001035808
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 153 TELQRRNEE 161
>NP_061845
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLVQRSNEE 9
           T +QR NEE
Sbjct: 221 TELQRRNEE 229
>NP_003592
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TLVQRSNEE 9
            TL++R N E
Sbjct: 1006 TLIERENME 1014
>NP_803876
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           +++QR NEE
Sbjct: 294 SILQRLNEE 302
>NP_001257321
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           +++QR NEE
Sbjct: 282 SILQRLNEE 290
>NP_001257320
          Length = 303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           +++QR NEE
Sbjct: 260 SILQRLNEE 268
>NP_958834
          Length = 369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLVQRSNEE 9
           +++QR NEE
Sbjct: 326 SILQRLNEE 334
>NP_001271286
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LVQRSNEE 9
          ++QRS+EE
Sbjct: 70 ILQRSSEE 77
>NP_001185947
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LVQRSNEE 9
          ++QRS+EE
Sbjct: 36 ILQRSSEE 43
>NP_001185946
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LVQRSNEE 9
          ++QRS+EE
Sbjct: 85 ILQRSSEE 92
>NP_079007
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          T++QR NE+
Sbjct: 31 TVLQRLNEQ 39
>NP_060161
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LVQRSNEE 9
          ++QRS+EE
Sbjct: 80 ILQRSSEE 87
>XP_005256206
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          T++QR NE+
Sbjct: 31 TVLQRLNEQ 39
>NP_006133
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLVQRSNEE 9
          ++ Q+SNEE
Sbjct: 64 SIEQKSNEE 72
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.112    0.257 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,539
Number of extensions: 794
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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