Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_997264                                                              17    3301
NP_001108488                                                           17    4312
XP_005264049                                                           17    4312
XP_006712694                                                           17    4312
XP_006712693                                                           17    4312
XP_005264045                                                           17    4312
XP_005264044                                                           17    4312
XP_005264043                                                           17    4312
XP_005264042                                                           17    4312
XP_005264041                                                           17    4312
XP_005264040                                                           17    4312
XP_005264039                                                           17    4312
XP_005264038                                                           17    4312
XP_006712692                                                           17    4312
XP_005264037                                                           17    4312
NP_001275582                                                           16    5631
NP_004850                                                              16    5631
NP_079385                                                              16    5631
NP_001157207                                                           16    5631
NP_001399                                                              16    5631
XP_006725418                                                           16    5631
XP_006725417                                                           16    5631
XP_006725416                                                           16    5631
XP_006725415                                                           16    5631
XP_006725414                                                           16    5631
XP_005257754                                                           16    5631
XP_005257753                                                           16    5631
XP_006722172                                                           16    5631
XP_006722171                                                           16    5631
XP_006722170                                                           16    5631
XP_005257069                                                           16    5631
XP_006710468                                                           16    5631
XP_005270637                                                           16    5631
NP_060034                                                              15    9605
NP_073619                                                              15    9605
NP_056190                                                              15    9605
NP_955749                                                              15    9605
NP_003165                                                              15    9605
NP_001035026                                                           15    9605
NP_068506                                                              15    9605
NP_001154901                                                           15    9605
NP_036273                                                              15    9605
NP_659437                                                              15    9605
XP_005266398                                                           15    9605
XP_005266397                                                           15    9605
XP_006719255                                                           15    9605
XP_006719254                                                           15    9605
XP_006719253                                                           15    9605
XP_006719252                                                           15    9605
XP_006719251                                                           15    9605
XP_006719250                                                           15    9605
XP_006717559                                                           15    9605
XP_006717558                                                           15    9605
XP_006717557                                                           15    9605
XP_006717556                                                           15    9605
XP_005252630                                                           15    9605
XP_005252629                                                           15    9605
XP_005252628                                                           15    9605
XP_005252627                                                           15    9605
XP_005252626                                                           15    9605
XP_005252625                                                           15    9605
XP_005252624                                                           15    9605
XP_005252623                                                           15    9605
XP_005252622                                                           15    9605
XP_006717555                                                           15    9605
XP_005252621                                                           15    9605
XP_006714518                                                           15    9605
XP_006714517                                                           15    9605
XP_006714516                                                           15    9605
XP_006714515                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TL TRLIET
Sbjct: 508 TLPTRLIET 516
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TL TRLIET
Sbjct: 303 TLPTRLIET 311
>NP_997264
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  TLQTRLI 7
          TLQTRLI
Sbjct: 39 TLQTRLI 45
>NP_001108488
          Length = 878

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 701 TLQSRLVAT 709
>XP_005264049
          Length = 712

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 521 TLQSRLVAT 529
>XP_006712694
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 614 TLQSRLVAT 622
>XP_006712693
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 640 TLQSRLVAT 648
>XP_005264045
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 640 TLQSRLVAT 648
>XP_005264044
          Length = 876

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 699 TLQSRLVAT 707
>XP_005264043
          Length = 879

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 699 TLQSRLVAT 707
>XP_005264042
          Length = 892

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 701 TLQSRLVAT 709
>XP_005264041
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 727 TLQSRLVAT 735
>XP_005264040
          Length = 905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 725 TLQSRLVAT 733
>XP_005264039
          Length = 907

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 727 TLQSRLVAT 735
>XP_005264038
          Length = 918

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 727 TLQSRLVAT 735
>XP_006712692
          Length = 918

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 727 TLQSRLVAT 735
>XP_005264037
          Length = 918

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLQTRLIET 9
           TLQ+RL+ T
Sbjct: 727 TLQSRLVAT 735
>NP_001275582
          Length = 1679

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 584 LQTRLLE 590
>NP_004850
          Length = 1675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 580 LQTRLLE 586
>NP_079385
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 652 LQTRLLE 658
>NP_001157207
          Length = 970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 852 LQTRLLE 858
>NP_001399
          Length = 2923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLQTRLIET 9
            T+Q RL+ET
Sbjct: 2303 TVQFRLLET 2311
>XP_006725418
          Length = 705

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 587 LQTRLLE 593
>XP_006725417
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 607 LQTRLLE 613
>XP_006725416
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 690 LQTRLLE 696
>XP_006725415
          Length = 990

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 872 LQTRLLE 878
>XP_006725414
          Length = 1034

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 916 LQTRLLE 922
>XP_005257754
          Length = 705

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 587 LQTRLLE 593
>XP_005257753
          Length = 707

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 589 LQTRLLE 595
>XP_006722172
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 690 LQTRLLE 696
>XP_006722171
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 854 LQTRLLE 860
>XP_006722170
          Length = 1016

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 898 LQTRLLE 904
>XP_005257069
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL+E
Sbjct: 580 LQTRLLE 586
>XP_006710468
          Length = 2916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLQTRLIET 9
            T+Q RL+ET
Sbjct: 2303 TVQFRLLET 2311
>XP_005270637
          Length = 2921

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLQTRLIET 9
            T+Q RL+ET
Sbjct: 2303 TVQFRLLET 2311
>NP_060034
          Length = 2551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TLQTRL 6
            TLQTRL
Sbjct: 2396 TLQTRL 2401
>NP_073619
          Length = 1183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TLQTRL 6
            TLQTRL
Sbjct: 1143 TLQTRL 1148
>NP_056190
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL++
Sbjct: 351 LQTRLVD 357
>NP_955749
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LQTRLIE 8
           LQTRL++
Sbjct: 351 LQTRLVD 357
>NP_003165
          Length = 1788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1028 VQTRLVE 1034
>NP_001035026
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           +LQTRLI
Sbjct: 827 SLQTRLI 833
>NP_068506
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1454 VQTRLVE 1460
>NP_001154901
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           TLQ+RLI
Sbjct: 361 TLQSRLI 367
>NP_036273
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           +LQTRLI
Sbjct: 840 SLQTRLI 846
>NP_659437
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           TLQ+RLI
Sbjct: 336 TLQSRLI 342
>XP_005266398
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           +LQTRLI
Sbjct: 408 SLQTRLI 414
>XP_005266397
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           +LQTRLI
Sbjct: 662 SLQTRLI 668
>XP_006719255
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLQTRL 6
           TLQTRL
Sbjct: 445 TLQTRL 450
>XP_006719254
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLQTRL 6
           TLQTRL
Sbjct: 770 TLQTRL 775
>XP_006719253
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLQTRL 6
           TLQTRL
Sbjct: 991 TLQTRL 996
>XP_006719252
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLQTRL 6
           TLQTRL
Sbjct: 991 TLQTRL 996
>XP_006719251
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TLQTRL 6
            TLQTRL
Sbjct: 1076 TLQTRL 1081
>XP_006719250
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TLQTRL 6
            TLQTRL
Sbjct: 1101 TLQTRL 1106
>XP_006717559
          Length = 1866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1106 VQTRLVE 1112
>XP_006717558
          Length = 1908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1148 VQTRLVE 1154
>XP_006717557
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1180 VQTRLVE 1186
>XP_006717556
          Length = 2024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1264 VQTRLVE 1270
>XP_005252630
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252629
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252628
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252627
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252626
          Length = 2260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1500 VQTRLVE 1506
>XP_005252625
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1517 VQTRLVE 1523
>XP_005252624
          Length = 2292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1532 VQTRLVE 1538
>XP_005252623
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1542 VQTRLVE 1548
>XP_005252622
          Length = 2308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1548 VQTRLVE 1554
>XP_006717555
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1568 VQTRLVE 1574
>XP_005252621
          Length = 2334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQTRLIE 8
            +QTRL+E
Sbjct: 1574 VQTRLVE 1580
>XP_006714518
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           TLQ+RLI
Sbjct: 316 TLQSRLI 322
>XP_006714517
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           TLQ+RLI
Sbjct: 336 TLQSRLI 342
>XP_006714516
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           TLQ+RLI
Sbjct: 341 TLQSRLI 347
>XP_006714515
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLQTRLI 7
           TLQ+RLI
Sbjct: 361 TLQSRLI 367
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.129    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 348,328
Number of extensions: 649
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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