Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155048                                                           19     665
NP_056404                                                              19     665
NP_001191195                                                           17    4312
NP_001191196                                                           17    4312
NP_000800                                                              17    4312
NP_001123465                                                           17    4312
NP_001070254                                                           17    4312
XP_006718387                                                           17    4312
XP_006718386                                                           17    4312
XP_006714066                                                           17    4312
XP_005264664                                                           17    4312
XP_005264663                                                           17    4312
XP_005264662                                                           17    4312
NP_115895                                                              17    4312
NP_004351                                                              16    5631
NP_000799                                                              16    5631
NP_872393                                                              16    5631
XP_005274716                                                           16    5631
XP_005251865                                                           16    5631
XP_005251864                                                           16    5631
XP_006712515                                                           16    5631
XP_006712513                                                           16    5631
XP_006712512                                                           16    5631
XP_006712511                                                           16    5631
XP_006712510                                                           16    5631
XP_006712509                                                           16    5631
XP_005246533                                                           16    5631
XP_006712508                                                           16    5631
NP_115893                                                              16    5631
NP_055745                                                              16    5631
NP_031377                                                              16    7355
XP_005262913                                                           16    7355
NP_001273659                                                           15    9605
NP_061869                                                              15    9605
NP_001136112                                                           15    9605
NP_112092                                                              15    9605
NP_536856                                                              15    9605
NP_663612                                                              15    9605
XP_006724281                                                           15    9605
XP_006724280                                                           15    9605
XP_006722063                                                           15    9605
XP_006722062                                                           15    9605
XP_006722061                                                           15    9605
XP_006722060                                                           15    9605
XP_005257605                                                           15    9605
XP_005257604                                                           15    9605
XP_006722059                                                           15    9605
XP_005251914                                                           15    9605
XP_006717092                                                           15    9605
XP_006717091                                                           15    9605
XP_005251912                                                           15    9605
XP_006717090                                                           15    9605
>NP_001155048
          Length = 630

 Score = 19.2 bits (38), Expect =   665
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TLNTVGTTT 9
           T+NT+GT+T
Sbjct: 228 TINTIGTST 236
>NP_056404
          Length = 718

 Score = 19.2 bits (38), Expect =   665
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TLNTVGTTT 9
           T+NT+GT+T
Sbjct: 228 TINTIGTST 236
>NP_001191195
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLNTVGTT 8
           T+NT+G T
Sbjct: 470 TVNTIGAT 477
>NP_001191196
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLNTVGTT 8
           T+NT+G T
Sbjct: 419 TVNTIGAT 426
>NP_000800
          Length = 554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLNTVGTT 8
           T+NT+G T
Sbjct: 489 TVNTIGAT 496
>NP_001123465
          Length = 718

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLNTVGT 7
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>NP_001070254
          Length = 1735

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT GT T
Sbjct: 1274 TANTTGTAT 1282
>XP_006718387
          Length = 1798

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT GT T
Sbjct: 1337 TANTTGTAT 1345
>XP_006718386
          Length = 1822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT GT T
Sbjct: 1337 TANTTGTAT 1345
>XP_006714066
          Length = 544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLNTVGTT 8
           T+NT+G T
Sbjct: 479 TVNTIGAT 486
>XP_005264664
          Length = 572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLNTVGT 7
           +LNTVGT
Sbjct: 283 SLNTVGT 289
>XP_005264663
          Length = 707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLNTVGT 7
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>XP_005264662
          Length = 710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLNTVGT 7
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>NP_115895
          Length = 707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLNTVGT 7
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>NP_004351
          Length = 882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           TLNTVG
Sbjct: 115 TLNTVG 120
>NP_000799
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TLNTVGTT 8
           T N VGTT
Sbjct: 395 TFNIVGTT 402
>NP_872393
          Length = 3234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2915 SISTVGTST 2923
>XP_005274716
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TLNTVGTT 8
           T N VGTT
Sbjct: 394 TFNIVGTT 401
>XP_005251865
          Length = 682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLNTVG 6
          TLNTVG
Sbjct: 13 TLNTVG 18
>XP_005251864
          Length = 683

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLNTVG 6
          TLNTVG
Sbjct: 13 TLNTVG 18
>XP_006712515
          Length = 3232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2913 SISTVGTST 2921
>XP_006712513
          Length = 3220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2882 SISTVGTST 2890
>XP_006712512
          Length = 3237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2918 SISTVGTST 2926
>XP_006712511
          Length = 3256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2918 SISTVGTST 2926
>XP_006712510
          Length = 3305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2986 SISTVGTST 2994
>XP_006712509
          Length = 3319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2981 SISTVGTST 2989
>XP_005246533
          Length = 3323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2985 SISTVGTST 2993
>XP_006712508
          Length = 3324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2986 SISTVGTST 2994
>NP_115893
          Length = 3258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    TLNTVGTTT 9
            +++TVGT+T
Sbjct: 2920 SISTVGTST 2928
>NP_055745
          Length = 683

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLNTVG 6
          TLNTVG
Sbjct: 13 TLNTVG 18
>NP_031377
          Length = 1228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TLNTVGTT 8
           +LNTVG T
Sbjct: 155 SLNTVGGT 162
>XP_005262913
          Length = 1193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TLNTVGTT 8
           +LNTVG T
Sbjct: 155 SLNTVGGT 162
>NP_001273659
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 531 TINTVG 536
>NP_061869
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TLNTVGTTT 9
           T NT  TTT
Sbjct: 757 TTNTTTTTT 765
>NP_001136112
          Length = 1726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TLNTVGTTT 9
           T NT  TTT
Sbjct: 757 TTNTTTTTT 765
>NP_112092
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NTVGTTT 9
           N+VGTT+
Sbjct: 121 NSVGTTS 127
>NP_536856
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 531 TINTVG 536
>NP_663612
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NTVGTTT 9
           N+VGTT+
Sbjct: 121 NSVGTTS 127
>XP_006724281
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NTVGTTT 9
           N+VGTT+
Sbjct: 121 NSVGTTS 127
>XP_006724280
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NTVGTTT 9
           N+VGTT+
Sbjct: 199 NSVGTTS 205
>XP_006722063
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_006722062
          Length = 1866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_006722061
          Length = 1913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_006722060
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_005257605
          Length = 1926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_005257604
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_006722059
          Length = 1965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    TLNTVGTTT 9
            T NT  TTT
Sbjct: 993  TTNTTTTTT 1001
>XP_005251914
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 498 TINTVG 503
>XP_006717092
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 549 TINTVG 554
>XP_006717091
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 549 TINTVG 554
>XP_005251912
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 531 TINTVG 536
>XP_006717090
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLNTVG 6
           T+NTVG
Sbjct: 549 TINTVG 554
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.112    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 403,574
Number of extensions: 601
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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