Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     869
NP_444254                                                              19     869
NP_444253                                                              19     869
NP_444255                                                              19     869
XP_005247551                                                           19     869
XP_005247550                                                           19     869
XP_006713712                                                           19     869
XP_005247549                                                           19     869
NP_899631                                                              17    4312
NP_899630                                                              17    4312
NP_003707                                                              17    4312
XP_006713441                                                           17    4312
XP_006713440                                                           17    4312
XP_006713439                                                           17    4312
XP_006713438                                                           17    4312
XP_006713437                                                           17    4312
XP_006713436                                                           17    4312
XP_006713435                                                           17    4312
XP_006713434                                                           17    4312
XP_006713433                                                           17    4312
XP_006713432                                                           17    4312
XP_006713431                                                           17    4312
XP_006713430                                                           17    4312
XP_006713429                                                           17    4312
XP_006713428                                                           17    4312
XP_006713427                                                           17    4312
XP_006713426                                                           17    4312
XP_006713425                                                           17    4312
NP_940969                                                              16    7355
XP_005265966                                                           16    7355
NP_061875                                                              15    9605
NP_001009571                                                           15    9605
NP_060424                                                              15    9605
NP_001161412                                                           15    9605
NP_038203                                                              15    9605
NP_149107                                                              15    9605
NP_002152                                                              15    9605
NP_898885                                                              15    9605
XP_005268266                                                           15    9605
XP_005268265                                                           15    9605
XP_005250765                                                           15    9605
XP_005250764                                                           15    9605
XP_005250763                                                           15    9605
XP_005250762                                                           15    9605
XP_005250761                                                           15    9605
XP_005250760                                                           15    9605
XP_005250759                                                           15    9605
XP_005250758                                                           15    9605
XP_005250757                                                           15    9605
XP_005250756                                                           15    9605
XP_005250755                                                           15    9605
XP_005250754                                                           15    9605
XP_005250753                                                           15    9605
XP_005250752                                                           15    9605
XP_005264434                                                           15    9605
XP_005264433                                                           15    9605
XP_005264432                                                           15    9605
XP_005264431                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           TLNAK VES
Sbjct: 933 TLNAKAVES 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1063 TLNGKTLKT 1071
>NP_444254
          Length = 1845

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           TLNAK VES
Sbjct: 933 TLNAKAVES 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1063 TLNGKTLKT 1071
>NP_444253
          Length = 1914

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLNAK VES
Sbjct: 1002 TLNAKAVES 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1132 TLNGKTLKT 1140
>NP_444255
          Length = 1863

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLNAK VES
Sbjct: 1002 TLNAKAVES 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1132 TLNGKTLKT 1140
>XP_005247551
          Length = 1855

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           TLNAK VES
Sbjct: 943 TLNAKAVES 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1073 TLNGKTLKT 1081
>XP_005247550
          Length = 1856

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLNAK VES
Sbjct: 1012 TLNAKAVES 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1142 TLNGKTLKT 1150
>XP_006713712
          Length = 1923

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLNAK VES
Sbjct: 1012 TLNAKAVES 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1142 TLNGKTLKT 1150
>XP_005247549
          Length = 1924

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLNAK VES
Sbjct: 1012 TLNAKAVES 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN KT+++
Sbjct: 1142 TLNGKTLKT 1150
>NP_899631
          Length = 1314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1270 TLNSKTYET 1278
>NP_899630
          Length = 1274

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1230 TLNSKTYET 1238
>NP_003707
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1309 TLNSKTYET 1317
>XP_006713441
          Length = 1125

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1081 TLNSKTYET 1089
>XP_006713440
          Length = 1127

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1083 TLNSKTYET 1091
>XP_006713439
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1090 TLNSKTYET 1098
>XP_006713438
          Length = 1148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1104 TLNSKTYET 1112
>XP_006713437
          Length = 1154

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1110 TLNSKTYET 1118
>XP_006713436
          Length = 1164

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1120 TLNSKTYET 1128
>XP_006713435
          Length = 1174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1130 TLNSKTYET 1138
>XP_006713434
          Length = 1180

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1136 TLNSKTYET 1144
>XP_006713433
          Length = 1183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1139 TLNSKTYET 1147
>XP_006713432
          Length = 1184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1140 TLNSKTYET 1148
>XP_006713431
          Length = 1190

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1146 TLNSKTYET 1154
>XP_006713430
          Length = 1197

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1153 TLNSKTYET 1161
>XP_006713429
          Length = 1203

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1159 TLNSKTYET 1167
>XP_006713428
          Length = 1206

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1162 TLNSKTYET 1170
>XP_006713427
          Length = 1207

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1163 TLNSKTYET 1171
>XP_006713426
          Length = 1210

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1166 TLNSKTYET 1174
>XP_006713425
          Length = 1213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT E+
Sbjct: 1169 TLNSKTYET 1177
>NP_940969
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NAKTVE 8
           NAKTVE
Sbjct: 126 NAKTVE 131
>XP_005265966
          Length = 891

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NAKTVE 8
           NAKTVE
Sbjct: 560 NAKTVE 565
>NP_061875
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           T N+KTV++
Sbjct: 418 TFNSKTVKN 426
>NP_001009571
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1213 TLNSKTYDT 1221
>NP_060424
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1254 TLNSKTYDT 1262
>NP_001161412
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1258 TLNSKTYDT 1266
>NP_038203
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    TLNAKTV 7
            TLN KTV
Sbjct: 1245 TLNMKTV 1251
>NP_149107
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNAKTVES 9
           LN+KT+ S
Sbjct: 728 LNSKTIRS 735
>NP_002152
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    TLNAKTV 7
            TLN KTV
Sbjct: 1245 TLNMKTV 1251
>NP_898885
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LNAKTV 7
           LNAKTV
Sbjct: 235 LNAKTV 240
>XP_005268266
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNAKTVES 9
           LN+KT+ S
Sbjct: 622 LNSKTIRS 629
>XP_005268265
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNAKTVES 9
           LN+KT+ S
Sbjct: 740 LNSKTIRS 747
>XP_005250765
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1208 TLNSKTYDT 1216
>XP_005250764
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1216 TLNSKTYDT 1224
>XP_005250763
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1218 TLNSKTYDT 1226
>XP_005250762
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1218 TLNSKTYDT 1226
>XP_005250761
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1223 TLNSKTYDT 1231
>XP_005250760
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1226 TLNSKTYDT 1234
>XP_005250759
          Length = 1293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1251 TLNSKTYDT 1259
>XP_005250758
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1256 TLNSKTYDT 1264
>XP_005250757
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1258 TLNSKTYDT 1266
>XP_005250756
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1259 TLNSKTYDT 1267
>XP_005250755
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1261 TLNSKTYDT 1269
>XP_005250754
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1263 TLNSKTYDT 1271
>XP_005250753
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1263 TLNSKTYDT 1271
>XP_005250752
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLNAKTVES 9
            TLN+KT ++
Sbjct: 1266 TLNSKTYDT 1274
>XP_005264434
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           T N+KTV++
Sbjct: 335 TFNSKTVKN 343
>XP_005264433
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           T N+KTV++
Sbjct: 420 TFNSKTVKN 428
>XP_005264432
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           T N+KTV++
Sbjct: 420 TFNSKTVKN 428
>XP_005264431
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLNAKTVES 9
           T N+KTV++
Sbjct: 420 TFNSKTVKN 428
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289    0.103    0.233 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 264,944
Number of extensions: 296
Number of successful extensions: 66
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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