Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726410                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_006710143                                                           18    1935
XP_006710142                                                           18    1935
XP_006710141                                                           18    1935
NP_060597                                                              16    7355
NP_001159434                                                           16    7355
NP_776065                                                              16    7355
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1190 LLLSEATV 1197
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1234 LLLSEATV 1241
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1234 LLLSEATV 1241
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1037 LLLSEATV 1044
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1190 LLLSEATV 1197
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLLSEATV 9
           LLLSEATV
Sbjct: 241 LLLSEATV 248
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1190 LLLSEATV 1197
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1300 LLLSEATV 1307
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1234 LLLSEATV 1241
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1234 LLLSEATV 1241
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1237 LLLSEATV 1244
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1287 LLLSEATV 1294
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1300 LLLSEATV 1307
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1300 LLLSEATV 1307
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1397 LLLSEATV 1404
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LLLSEATV 9
            LLLSEATV
Sbjct: 1037 LLLSEATV 1044
>XP_006710143
          Length = 562

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LLLSEATV 9
          LLLSEATV
Sbjct: 76 LLLSEATV 83
>XP_006710142
          Length = 671

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLLSEATV 9
           LLLSEATV
Sbjct: 186 LLLSEATV 193
>XP_006710141
          Length = 672

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLLSEATV 9
           LLLSEATV
Sbjct: 186 LLLSEATV 193
>NP_060597
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLLLSEATV 9
           TLL+ EAT+
Sbjct: 681 TLLIHEATL 689
>NP_001159434
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLLLSEATV 9
           TLL+ EAT+
Sbjct: 641 TLLIHEATL 649
>NP_776065
          Length = 825

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLLLSEATV 9
           TLL+ EAT+
Sbjct: 680 TLLIHEATL 688
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.122    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 262,478
Number of extensions: 263
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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