Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              20     390
XP_005271924                                                           20     390
XP_005271923                                                           20     390
NP_005574                                                              18    1935
NP_003180                                                              18    1935
NP_001277333                                                           18    1935
NP_001277335                                                           18    1935
NP_001277332                                                           18    1935
NP_001277334                                                           18    1935
NP_001274276                                                           18    1935
NP_775886                                                              18    1935
XP_006726674                                                           18    1935
XP_005259969                                                           18    1935
XP_006722816                                                           18    1935
XP_006722815                                                           18    1935
XP_006721084                                                           18    1935
XP_006710926                                                           18    1935
XP_005271217                                                           18    1935
XP_005271216                                                           18    1935
XP_006710925                                                           18    1935
NP_065789                                                              17    2528
NP_689803                                                              17    3301
NP_001139201                                                           17    3301
NP_001139200                                                           17    3301
NP_001243195                                                           17    3301
NP_001139199                                                           17    3301
XP_006719102                                                           17    3301
NP_000205                                                              17    4312
NP_006304                                                              17    4312
NP_001239007                                                           17    4312
XP_005269318                                                           17    4312
XP_006719781                                                           17    4312
XP_005269316                                                           17    4312
NP_003150                                                              16    5631
NP_001032420                                                           16    5631
XP_005274642                                                           16    5631
XP_005274641                                                           16    5631
XP_006724574                                                           16    5631
NP_005889                                                              16    5631
NP_976240                                                              16    5631
NP_258428                                                              16    7355
NP_002855                                                              16    7355
NP_001185715                                                           15    9605
NP_001185712                                                           15    9605
NP_002688                                                              15    9605
NP_078941                                                              15    9605
NP_588609                                                              15    9605
NP_005638                                                              15    9605
NP_078812                                                              15    9605
XP_005262629                                                           15    9605
XP_005256281                                                           15    9605
XP_005256280                                                           15    9605
XP_005256278                                                           15    9605
XP_005256277                                                           15    9605
XP_005247832                                                           15    9605
XP_006713809                                                           15    9605
XP_006713808                                                           15    9605
XP_005247829                                                           15    9605
XP_005247828                                                           15    9605
NP_001182660                                                           15    9605
NP_005412                                                              15    9605
NP_001132940                                                           15    9605
NP_001132938                                                           15    9605
NP_001132939                                                           15    9605
NP_599021                                                              15    9605
NP_150600                                                              15    9605
NP_599020                                                              15    9605
>NP_001261
          Length = 1710

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLKQQNVNG 9
           TLKQQNV G
Sbjct: 337 TLKQQNVRG 345
>XP_005271924
          Length = 1710

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLKQQNVNG 9
           TLKQQNV G
Sbjct: 337 TLKQQNVRG 345
>XP_005271923
          Length = 1798

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLKQQNVNG 9
           TLKQQNV G
Sbjct: 337 TLKQQNVRG 345
>NP_005574
          Length = 280

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 162 RQQNVNG 168
>NP_003180
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>NP_001277333
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>NP_001277335
          Length = 172

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  KQQNVNG 9
          +QQNVNG
Sbjct: 40 RQQNVNG 46
>NP_001277332
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>NP_001277334
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>NP_001274276
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>NP_775886
          Length = 1184

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LKQQNVNG 9
          LKQ+N+NG
Sbjct: 47 LKQKNMNG 54
>XP_006726674
          Length = 1205

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LKQQNVNG 9
          LKQ+N+NG
Sbjct: 47 LKQKNMNG 54
>XP_005259969
          Length = 206

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  KQQNVNG 9
          +QQNVNG
Sbjct: 88 RQQNVNG 94
>XP_006722816
          Length = 302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 184 RQQNVNG 190
>XP_006722815
          Length = 351

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 233 RQQNVNG 239
>XP_006721084
          Length = 1205

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LKQQNVNG 9
          LKQ+N+NG
Sbjct: 47 LKQKNMNG 54
>XP_006710926
          Length = 172

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  KQQNVNG 9
          +QQNVNG
Sbjct: 40 RQQNVNG 46
>XP_005271217
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>XP_005271216
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>XP_006710925
          Length = 331

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           +QQNVNG
Sbjct: 199 RQQNVNG 205
>NP_065789
          Length = 1771

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TLKQQNVNG 9
            T+K+ N+NG
Sbjct: 1236 TIKKANING 1244
>NP_689803
          Length = 388

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QQNVNG 9
           QQNVNG
Sbjct: 179 QQNVNG 184
>NP_001139201
          Length = 369

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QQNVNG 9
           QQNVNG
Sbjct: 200 QQNVNG 205
>NP_001139200
          Length = 409

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QQNVNG 9
           QQNVNG
Sbjct: 200 QQNVNG 205
>NP_001243195
          Length = 291

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QQNVNG 9
          QQNVNG
Sbjct: 82 QQNVNG 87
>NP_001139199
          Length = 325

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QQNVNG 9
           QQNVNG
Sbjct: 116 QQNVNG 121
>XP_006719102
          Length = 363

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QQNVNG 9
           QQNVNG
Sbjct: 154 QQNVNG 159
>NP_000205
          Length = 1218

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          L  QNVNG
Sbjct: 40 LSMQNVNG 47
>NP_006304
          Length = 952

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           K QN+NG
Sbjct: 606 KDQNING 612
>NP_001239007
          Length = 981

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           K QN+NG
Sbjct: 635 KDQNING 641
>XP_005269318
          Length = 648

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           K QN+NG
Sbjct: 302 KDQNING 308
>XP_006719781
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           K QN+NG
Sbjct: 635 KDQNING 641
>XP_005269316
          Length = 860

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           K QN+NG
Sbjct: 514 KDQNING 520
>NP_003150
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TLKQQNV 7
          TLKQ+N+
Sbjct: 66 TLKQENI 72
>NP_001032420
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TLKQQNV 7
          TLKQ+N+
Sbjct: 66 TLKQENI 72
>XP_005274642
          Length = 984

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TLKQQNV 7
          TLKQ+N+
Sbjct: 66 TLKQENI 72
>XP_005274641
          Length = 1001

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TLKQQNV 7
          TLKQ+N+
Sbjct: 66 TLKQENI 72
>XP_006724574
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TLKQQNV 7
          TLKQ+N+
Sbjct: 66 TLKQENI 72
>NP_005889
          Length = 709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLKQQN 6
           TLKQQN
Sbjct: 534 TLKQQN 539
>NP_976240
          Length = 694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLKQQN 6
           TLKQQN
Sbjct: 534 TLKQQN 539
>NP_258428
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QQNVNG 9
           +QNVNG
Sbjct: 665 EQNVNG 670
>NP_002855
          Length = 1482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LKQQNVNG 9
            +KQQN  G
Sbjct: 1245 MKQQNAQG 1252
>NP_001185715
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKQQNVN 8
           L+QQN+N
Sbjct: 142 LQQQNLN 148
>NP_001185712
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKQQNVN 8
           L+QQN+N
Sbjct: 194 LQQQNLN 200
>NP_002688
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKQQNVN 8
           L+QQN+N
Sbjct: 205 LQQQNLN 211
>NP_078941
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>NP_588609
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           K+QNV+G
Sbjct: 96  KKQNVDG 102
>NP_005638
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 85 ISQSNING 92
>NP_078812
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           KQQ VNG
Sbjct: 445 KQQLVNG 451
>XP_005262629
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 48 ISQSNING 55
>XP_005256281
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           K+QNV+G
Sbjct: 96  KKQNVDG 102
>XP_005256280
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           K+QNV+G
Sbjct: 96  KKQNVDG 102
>XP_005256278
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           K+QNV+G
Sbjct: 96  KKQNVDG 102
>XP_005256277
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQQNVNG 9
           K+QNV+G
Sbjct: 96  KKQNVDG 102
>XP_005247832
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>XP_006713809
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>XP_006713808
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>XP_005247829
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>XP_005247828
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 44 ISQSNING 51
>NP_001182660
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KQQNVNG 9
           KQQ VNG
Sbjct: 283 KQQLVNG 289
>NP_005412
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  KQQNVN 8
          +QQNVN
Sbjct: 14 RQQNVN 19
>NP_001132940
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>NP_001132938
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 85 ISQSNING 92
>NP_001132939
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>NP_599021
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>NP_150600
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
>NP_599020
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2  LKQQNVNG 9
          + Q N+NG
Sbjct: 34 ISQSNING 41
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.120    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 517,807
Number of extensions: 913
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package