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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000360                                                              17    3301
XP_005268094                                                           17    3301
NP_003205                                                              17    4312
NP_001035022                                                           16    5631
NP_067613                                                              16    5631
NP_000617                                                              16    5631
XP_005257915                                                           16    5631
NP_115943                                                              16    5631
NP_001137300                                                           16    7355
NP_001153638                                                           16    7355
NP_067637                                                              16    7355
XP_005270532                                                           16    7355
NP_795370                                                              16    7355
NP_777556                                                              16    7355
NP_795368                                                              16    7355
NP_004942                                                              15    9605
NP_001091112                                                           15    9605
NP_689418                                                              15    9605
NP_001248383                                                           15    9605
NP_001248381                                                           15    9605
NP_001248384                                                           15    9605
NP_001248382                                                           15    9605
NP_005270                                                              15    9605
NP_001091669                                                           15    9605
NP_001166245                                                           15    9605
XP_006723108                                                           15    9605
XP_005258618                                                           15    9605
XP_005246528                                                           15    9605
XP_006712500                                                           15    9605
NP_997208                                                              15    9605

>NP_000360
          Length = 764

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLIIVAFVI 9
           TL IVAFVI
Sbjct: 588 TLNIVAFVI 596



>XP_005268094
          Length = 764

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLIIVAFVI 9
           TL IVAFVI
Sbjct: 588 TLNIVAFVI 596



>NP_003205
          Length = 435

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TLIIVAFV 8
           TL+++AFV
Sbjct: 408 TLLVIAFV 415



>NP_001035022
          Length = 230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLIIVAFVI 9
           TL+I+ F+I
Sbjct: 167 TLLIILFII 175



>NP_067613
          Length = 125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLIIVAFVI 9
          TL+I+ F+I
Sbjct: 62 TLLIILFII 70



>NP_000617
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLIIVAFVI 9
           TL+I+ F+I
Sbjct: 166 TLLIILFII 174



>XP_005257915
          Length = 126

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TLIIVAFVI 9
          TL+I+ F+I
Sbjct: 63 TLLIILFII 71



>NP_115943
          Length = 346

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LIIVAFVI 9
          L+IVAFV+
Sbjct: 21 LLIVAFVL 28



>NP_001137300
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LIIVAFVI 9
          L+I+AFV+
Sbjct: 35 LVILAFVV 42



>NP_001153638
          Length = 67

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LIIVAFVI 9
          L+I+AFV+
Sbjct: 35 LVILAFVV 42



>NP_067637
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LIIVAFVI 9
          L+I+AFV+
Sbjct: 35 LVILAFVV 42



>XP_005270532
          Length = 130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  TLIIVAFV 8
          TL+++AF+
Sbjct: 51 TLLLIAFI 58



>NP_795370
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  LIIVAFVI 9
          L++VAF++
Sbjct: 12 LVVVAFIL 19



>NP_777556
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  TLIIVAFV 8
          TL+++AF+
Sbjct: 51 TLLLIAFI 58



>NP_795368
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LIIVAFVI 9
          LI+V FVI
Sbjct: 12 LIVVTFVI 19



>NP_004942
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LIIVAFVI 9
           LIIV FV+
Sbjct: 248 LIIVVFVL 255



>NP_001091112
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LIIVAFVI 9
          LI+V FVI
Sbjct: 12 LIVVIFVI 19



>NP_689418
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   TLIIVAFVI 9
           TL++VA+++
Sbjct: 609 TLLLVAYMV 617



>NP_001248383
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_001248381
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_001248384
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_001248382
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_005270
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_001091669
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_001166245
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IIVAFVI 9
           +IVAFV+
Sbjct: 429 VIVAFVV 435



>XP_006723108
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IIVAFVI 9
           +IVAFV+
Sbjct: 233 VIVAFVV 239



>XP_005258618
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IIVAFVI 9
           +IVAFV+
Sbjct: 395 VIVAFVV 401



>XP_005246528
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>XP_006712500
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIIVAFVI 9
           +++VAFV+
Sbjct: 250 VVVVAFVV 257



>NP_997208
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IIVAFVI 9
           +IVAFV+
Sbjct: 429 VIVAFVV 435



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.358    0.168    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 248,639
Number of extensions: 407
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)