Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001128643                                                           17    4312
NP_001128642                                                           17    4312
NP_689548                                                              17    4312
NP_114117                                                              17    4312
NP_056326                                                              17    4312
NP_001258803                                                           17    4312
XP_006723833                                                           17    4312
XP_005260442                                                           17    4312
NP_116023                                                              16    5631
NP_443179                                                              16    5631
XP_005266703                                                           16    5631
XP_005251676                                                           16    5631
NP_000766                                                              16    7355
NP_056078                                                              16    7355
NP_001167587                                                           16    7355
NP_001167588                                                           16    7355
XP_005254315                                                           16    7355
XP_005254314                                                           16    7355
XP_006720509                                                           16    7355
XP_005254313                                                           16    7355
XP_005254312                                                           16    7355
NP_002144                                                              16    7355
NP_001269607                                                           15    9605
NP_000457                                                              15    9605
NP_064592                                                              15    9605
NP_001599                                                              15    9605
NP_001273433                                                           15    9605
NP_001273432                                                           15    9605
NP_006635                                                              15    9605
NP_001273434                                                           15    9605
NP_004614                                                              15    9605
NP_000536                                                              15    9605
NP_001239049                                                           15    9605
NP_055963                                                              15    9605
NP_001239053                                                           15    9605
NP_001239051                                                           15    9605
NP_001239048                                                           15    9605
XP_005257359                                                           15    9605
XP_006719820                                                           15    9605
XP_005266293                                                           15    9605
XP_005252384                                                           15    9605
XP_005250490                                                           15    9605
XP_005250486                                                           15    9605
XP_005246574                                                           15    9605
XP_005247048                                                           15    9605
XP_005247047                                                           15    9605
XP_006711950                                                           15    9605
XP_005264750                                                           15    9605
NP_005524                                                              15    9605
NP_057114                                                              15    9605
>NP_001128643
          Length = 289

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LEVFFSD 8
           LE+FF+D
Sbjct: 247 LEIFFTD 253
>NP_001128642
          Length = 296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LEVFFSD 8
           LE+FF+D
Sbjct: 254 LEIFFTD 260
>NP_689548
          Length = 531

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LEVFFSDT 9
           L VFFS+T
Sbjct: 146 LSVFFSET 153
>NP_114117
          Length = 289

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LEVFFSD 8
           LE+FF+D
Sbjct: 247 LEIFFTD 253
>NP_056326
          Length = 384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLEVFFS 7
           TL+VFFS
Sbjct: 327 TLQVFFS 333
>NP_001258803
          Length = 384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLEVFFS 7
           TL+VFFS
Sbjct: 327 TLQVFFS 333
>XP_006723833
          Length = 384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLEVFFS 7
           TL+VFFS
Sbjct: 327 TLQVFFS 333
>XP_005260442
          Length = 384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TLEVFFS 7
           TL+VFFS
Sbjct: 327 TLQVFFS 333
>NP_116023
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LEVFFSDT 9
           L VFFSD+
Sbjct: 557 LAVFFSDS 564
>NP_443179
          Length = 2170

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLEVFF 6
           TLEVFF
Sbjct: 859 TLEVFF 864
>XP_005266703
          Length = 1501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TLEVFF 6
           TLEVFF
Sbjct: 190 TLEVFF 195
>XP_005251676
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LEVFFSDT 9
           L VFFSD+
Sbjct: 557 LAVFFSDS 564
>NP_000766
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TLEVFFSDT 9
           TL++FF+ T
Sbjct: 305 TLDLFFAGT 313
>NP_056078
          Length = 3036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2488 DAFFSDT 2494
>NP_001167587
          Length = 3037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2489 DAFFSDT 2495
>NP_001167588
          Length = 2400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 1852 DAFFSDT 1858
>XP_005254315
          Length = 2576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2489 DAFFSDT 2495
>XP_005254314
          Length = 2605

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2489 DAFFSDT 2495
>XP_006720509
          Length = 2646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2489 DAFFSDT 2495
>XP_005254313
          Length = 3057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2488 DAFFSDT 2494
>XP_005254312
          Length = 3058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    EVFFSDT 9
            + FFSDT
Sbjct: 2489 DAFFSDT 2495
>NP_002144
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2 LEVFFSDT 9
         +  FFSDT
Sbjct: 1 MSTFFSDT 8
>NP_001269607
          Length = 1075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TLEVFFSD 8
           TLEV FS+
Sbjct: 435 TLEVAFSE 442
>NP_000457
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TLEVFFSD 8
           TLEV FS+
Sbjct: 643 TLEVAFSE 650
>NP_064592
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    EVFFSD 8
            EVFF+D
Sbjct: 1359 EVFFND 1364
>NP_001599
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TLEVFFSD 8
           T E+FF D
Sbjct: 258 TAELFFED 265
>NP_001273433
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LE F+SD
Sbjct: 444 LEAFYSD 450
>NP_001273432
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LE F+SD
Sbjct: 442 LEAFYSD 448
>NP_006635
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LE F+SD
Sbjct: 442 LEAFYSD 448
>NP_001273434
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LE F+SD
Sbjct: 366 LEAFYSD 372
>NP_004614
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LEV+F D
Sbjct: 325 LEVYFED 331
>NP_000536
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TLEVFFSDT 9
           T +VF SDT
Sbjct: 539 TKQVFTSDT 547
>NP_001239049
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 745 ELFFSD 750
>NP_055963
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 745 ELFFSD 750
>NP_001239053
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 745 ELFFSD 750
>NP_001239051
          Length = 1288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 710 ELFFSD 715
>NP_001239048
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 745 ELFFSD 750
>XP_005257359
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LEVFFSDT 9
           LE+FF  T
Sbjct: 155 LEIFFGKT 162
>XP_006719820
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LE F+SD
Sbjct: 497 LEAFYSD 503
>XP_005266293
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LEVFFSD 8
           LE F+SD
Sbjct: 444 LEAFYSD 450
>XP_005252384
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           EVFF+D
Sbjct: 639 EVFFND 644
>XP_005250490
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLEVFFSD 8
          TLEV FS+
Sbjct: 60 TLEVAFSE 67
>XP_005250486
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TLEVFFSD 8
           TLEV FS+
Sbjct: 603 TLEVAFSE 610
>XP_005246574
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TLEVFFSD 8
           T E+FF D
Sbjct: 237 TAELFFED 244
>XP_005247048
          Length = 1107

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 529 ELFFSD 534
>XP_005247047
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   EVFFSD 8
           E+FFSD
Sbjct: 559 ELFFSD 564
>XP_006711950
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   TLEVFFSDT 9
           +L  FF DT
Sbjct: 205 SLSTFFGDT 213
>XP_005264750
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   TLEVFFSDT 9
           +L  FF DT
Sbjct: 205 SLSTFFGDT 213
>NP_005524
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LEVFFSDT 9
           LE+FF  T
Sbjct: 157 LEIFFGKT 164
>NP_057114
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   TLEVFFSDT 9
           +L  FF DT
Sbjct: 205 SLSTFFGDT 213
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.138    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 463,685
Number of extensions: 975
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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