Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_777576                                                              18    1935
NP_055561                                                              17    3301
XP_005246260                                                           17    3301
XP_005246259                                                           17    3301
XP_005246258                                                           17    3301
XP_005246257                                                           17    3301
XP_006711972                                                           17    3301
NP_005693                                                              17    3301
NP_115495                                                              17    4312
NP_001269614                                                           17    4312
NP_001269613                                                           17    4312
NP_078957                                                              17    4312
NP_001269615                                                           17    4312
XP_005261801                                                           17    4312
XP_005261800                                                           17    4312
XP_005261799                                                           17    4312
XP_005261798                                                           17    4312
NP_001093260                                                           16    5631
NP_001273310                                                           16    5631
NP_115824                                                              16    5631
NP_997299                                                              16    5631
NP_001273308                                                           16    5631
NP_001138669                                                           16    5631
NP_001273309                                                           16    5631
XP_005276416                                                           16    5631
XP_006725079                                                           16    5631
XP_006725078                                                           16    5631
XP_006715643                                                           16    5631
XP_006715642                                                           16    5631
NP_001160132                                                           16    7355
NP_061850                                                              16    7355
NP_851820                                                              16    7355
NP_543008                                                              16    7355
NP_039225                                                              16    7355
NP_001269340                                                           16    7355
NP_002703                                                              16    7355
NP_001269338                                                           16    7355
NP_001269343                                                           16    7355
NP_001269339                                                           16    7355
NP_001269342                                                           16    7355
NP_001269341                                                           16    7355
XP_005275582                                                           16    7355
XP_005275581                                                           16    7355
XP_005275423                                                           16    7355
XP_005275422                                                           16    7355
XP_005275288                                                           16    7355
XP_005275287                                                           16    7355
XP_005275147                                                           16    7355
XP_005275146                                                           16    7355
XP_005274992                                                           16    7355
XP_005274991                                                           16    7355
XP_005272846                                                           16    7355
XP_005272845                                                           16    7355
XP_005274901                                                           16    7355
XP_005274900                                                           16    7355
XP_005262336                                                           16    7355
XP_006724726                                                           16    7355
XP_006724725                                                           16    7355
XP_005254103                                                           16    7355
XP_005254102                                                           16    7355
XP_005254101                                                           16    7355
XP_005254100                                                           16    7355
XP_005249059                                                           16    7355
XP_005249058                                                           16    7355
NP_543146                                                              16    7355
NP_001107854                                                           15    9605
NP_001070651                                                           15    9605
NP_000539                                                              15    9605
XP_005255589                                                           15    9605
XP_005255588                                                           15    9605
XP_005255587                                                           15    9605
XP_005255586                                                           15    9605
XP_005255585                                                           15    9605
XP_005255584                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLCLKQKST 9
           T CLKQKST
Sbjct: 415 TPCLKQKST 423
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TLCLKQKST 9
           T CLKQKST
Sbjct: 210 TPCLKQKST 218
>NP_777576
          Length = 1749

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    CLKQKST 9
            CLKQK+T
Sbjct: 1577 CLKQKNT 1583
>NP_055561
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCLKQ
Sbjct: 44 TLCLKQ 49
>XP_005246260
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCLKQ
Sbjct: 44 TLCLKQ 49
>XP_005246259
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCLKQ
Sbjct: 44 TLCLKQ 49
>XP_005246258
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCLKQ
Sbjct: 44 TLCLKQ 49
>XP_005246257
          Length = 292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCLKQ
Sbjct: 44 TLCLKQ 49
>XP_006711972
          Length = 300

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCLKQ
Sbjct: 52 TLCLKQ 57
>NP_005693
          Length = 437

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQKS
Sbjct: 240 CLKQKS 245
>NP_115495
          Length = 6306

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    TLCLKQKS 8
            TLCLK+++
Sbjct: 2441 TLCLKEQA 2448
>NP_001269614
          Length = 225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 48 TLCREQKS 55
>NP_001269613
          Length = 321

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 48 TLCREQKS 55
>NP_078957
          Length = 297

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 48 TLCREQKS 55
>NP_001269615
          Length = 220

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 48 TLCREQKS 55
>XP_005261801
          Length = 315

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 48 TLCREQKS 55
>XP_005261800
          Length = 321

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 41 TLCREQKS 48
>XP_005261799
          Length = 345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 41 TLCREQKS 48
>XP_005261798
          Length = 345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TLCLKQKS 8
          TLC +QKS
Sbjct: 41 TLCREQKS 48
>NP_001093260
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LCLKQKS 8
           +CLK+KS
Sbjct: 153 VCLKEKS 159
>NP_001273310
          Length = 242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LCLKQKST 9
          LCL+ KST
Sbjct: 79 LCLQGKST 86
>NP_115824
          Length = 910

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 747 LCLQGKST 754
>NP_997299
          Length = 917

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLCLKQKS 8
           T+CL +KS
Sbjct: 857 TICLPEKS 864
>NP_001273308
          Length = 922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 759 LCLQGKST 766
>NP_001138669
          Length = 917

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLCLKQKS 8
           T+CL +KS
Sbjct: 857 TICLPEKS 864
>NP_001273309
          Length = 933

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 770 LCLQGKST 777
>XP_005276416
          Length = 1583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TLCLKQKS 8
           T+CL +KS
Sbjct: 846 TICLPEKS 853
>XP_006725079
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 747 LCLQGKST 754
>XP_006725078
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 747 LCLQGKST 754
>XP_006715643
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 747 LCLQGKST 754
>XP_006715642
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LCLKQKST 9
           LCL+ KST
Sbjct: 747 LCLQGKST 754
>NP_001160132
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CL+QKS
Sbjct: 311 CLRQKS 316
>NP_061850
          Length = 828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CL+QKS
Sbjct: 331 CLRQKS 336
>NP_851820
          Length = 848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CL+QKS
Sbjct: 351 CLRQKS 356
>NP_543008
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQK+
Sbjct: 234 CLKQKA 239
>NP_039225
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>NP_001269340
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCL+Q
Sbjct: 59 TLCLRQ 64
>NP_002703
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLCLKQ 6
           TLCL+Q
Sbjct: 102 TLCLRQ 107
>NP_001269338
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCL+Q
Sbjct: 59 TLCLRQ 64
>NP_001269343
          Length = 221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCL+Q
Sbjct: 43 TLCLRQ 48
>NP_001269339
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   TLCLKQ 6
           TLCL+Q
Sbjct: 102 TLCLRQ 107
>NP_001269342
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCL+Q
Sbjct: 43 TLCLRQ 48
>NP_001269341
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TLCLKQ 6
          TLCL+Q
Sbjct: 86 TLCLRQ 91
>XP_005275582
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275581
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275423
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275422
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275288
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275287
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275147
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005275146
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005274992
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005274991
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005272846
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005272845
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005274901
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005274900
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005262336
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CL+QKS
Sbjct: 351 CLRQKS 356
>XP_006724726
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CL+QKS
Sbjct: 234 CLRQKS 239
>XP_006724725
          Length = 785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CL+QKS
Sbjct: 288 CLRQKS 293
>XP_005254103
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQK+
Sbjct: 234 CLKQKA 239
>XP_005254102
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQK+
Sbjct: 234 CLKQKA 239
>XP_005254101
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQK+
Sbjct: 234 CLKQKA 239
>XP_005254100
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQK+
Sbjct: 234 CLKQKA 239
>XP_005249059
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>XP_005249058
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LCLKQKST 9
           LC+KQ  T
Sbjct: 306 LCIKQTET 313
>NP_543146
          Length = 1393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TLCLKQKST 9
            T+C K K+T
Sbjct: 1194 TICTKGKNT 1202
>NP_001107854
          Length = 1784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 696 CLKQES 701
>NP_001070651
          Length = 1740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 696 CLKQES 701
>NP_000539
          Length = 1807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 696 CLKQES 701
>XP_005255589
          Length = 1831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 787 CLKQES 792
>XP_005255588
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 787 CLKQES 792
>XP_005255587
          Length = 1854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 787 CLKQES 792
>XP_005255586
          Length = 1855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 787 CLKQES 792
>XP_005255585
          Length = 1875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 787 CLKQES 792
>XP_005255584
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CLKQKS 8
           CLKQ+S
Sbjct: 787 CLKQES 792
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.120    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 753,319
Number of extensions: 989
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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