Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           18    1135
NP_004561                                                              18    1135
NP_001275703                                                           18    1135
XP_005253450                                                           18    1135
XP_006719151                                                           18    1135
NP_001275658                                                           17    4312
NP_001275660                                                           17    4312
NP_004929                                                              17    4312
NP_001275659                                                           17    4312
XP_005251814                                                           17    4312
XP_006717051                                                           17    4312
NP_065996                                                              15    9605
XP_005270063                                                           15    9605
XP_005270062                                                           15    9605
XP_005270061                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TLAQMSAIN 9
            TLAQMSAI+
Sbjct: 1216 TLAQMSAIS 1224
>NP_004561
          Length = 1445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TLAQMSAIN 9
            TLAQMSAI+
Sbjct: 1175 TLAQMSAIS 1183
>NP_001275703
          Length = 1264

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TLAQMSAIN 9
            TLAQMSAI+
Sbjct: 994  TLAQMSAIS 1002
>XP_005253450
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TLAQMSAIN 9
            TLAQMSAI+
Sbjct: 1216 TLAQMSAIS 1224
>XP_006719151
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TLAQMSAIN 9
            TLAQMSAI+
Sbjct: 1216 TLAQMSAIS 1224
>NP_001275658
          Length = 1430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLAQMSAIN 9
           TLA +SA+N
Sbjct: 225 TLANVSAVN 233
>NP_001275660
          Length = 1430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLAQMSAIN 9
           TLA +SA+N
Sbjct: 225 TLANVSAVN 233
>NP_004929
          Length = 1430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLAQMSAIN 9
           TLA +SA+N
Sbjct: 225 TLANVSAVN 233
>NP_001275659
          Length = 1430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLAQMSAIN 9
           TLA +SA+N
Sbjct: 225 TLANVSAVN 233
>XP_005251814
          Length = 839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TLAQMSAIN 9
           TLA +SA+N
Sbjct: 225 TLANVSAVN 233
>XP_006717051
          Length = 1285

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TLAQMSAIN 9
          TLA +SA+N
Sbjct: 80 TLANVSAVN 88
>NP_065996
          Length = 3184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAQMSAIN 9
           L Q+SAIN
Sbjct: 591 LEQLSAIN 598
>XP_005270063
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAQMSAIN 9
           L Q+SAIN
Sbjct: 591 LEQLSAIN 598
>XP_005270062
          Length = 3184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAQMSAIN 9
           L Q+SAIN
Sbjct: 591 LEQLSAIN 598
>XP_005270061
          Length = 3184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAQMSAIN 9
           L Q+SAIN
Sbjct: 591 LEQLSAIN 598
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.112    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 177,787
Number of extensions: 151
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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