Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001165907                                                           17    4312
NP_476506                                                              17    4312
NP_002628                                                              17    4312
NP_476505                                                              17    4312
NP_004360                                                              17    4312
NP_476508                                                              17    4312
NP_001116142                                                           17    4312
NP_476507                                                              17    4312
XP_006724724                                                           17    4312
XP_005246123                                                           17    4312
XP_005246122                                                           17    4312
XP_006712316                                                           17    4312
NP_003699                                                              16    5631
NP_000843                                                              16    7355
NP_640337                                                              16    7355
NP_001121187                                                           16    7355
XP_006715402                                                           16    7355
NP_001137292                                                           15    9605
NP_001360                                                              15    9605
NP_005229                                                              15    9605
NP_001157017                                                           15    9605
NP_009178                                                              15    9605
NP_942583                                                              15    9605
NP_542117                                                              15    9605
NP_001157016                                                           15    9605
NP_001157018                                                           15    9605
NP_001157019                                                           15    9605
NP_055907                                                              15    9605
NP_005662                                                              15    9605
NP_001269128                                                           15    9605
NP_001269118                                                           15    9605
NP_064710                                                              15    9605
NP_000373                                                              15    9605
NP_938020                                                              15    9605
XP_006725374                                                           15    9605
XP_006725373                                                           15    9605
XP_006725372                                                           15    9605
XP_006725371                                                           15    9605
XP_006725370                                                           15    9605
XP_006725369                                                           15    9605
XP_006725368                                                           15    9605
XP_006725367                                                           15    9605
XP_006725366                                                           15    9605
XP_006725365                                                           15    9605
XP_006725364                                                           15    9605
XP_006724543                                                           15    9605
XP_006724542                                                           15    9605
XP_005274533                                                           15    9605
XP_005274532                                                           15    9605
XP_006724541                                                           15    9605
XP_005274531                                                           15    9605
XP_006724540                                                           15    9605
XP_005274530                                                           15    9605
XP_006721718                                                           15    9605
XP_006721717                                                           15    9605
XP_006721716                                                           15    9605
XP_005257045                                                           15    9605
XP_005257043                                                           15    9605
XP_005257042                                                           15    9605
XP_006721715                                                           15    9605
XP_005257040                                                           15    9605
XP_005257039                                                           15    9605
XP_005257038                                                           15    9605
XP_005257037                                                           15    9605
XP_005255493                                                           15    9605
XP_006721128                                                           15    9605
XP_005255492                                                           15    9605
XP_005255242                                                           15    9605
XP_005255241                                                           15    9605
XP_005255240                                                           15    9605
XP_005255239                                                           15    9605
XP_005271485                                                           15    9605
XP_005248319                                                           15    9605
NP_001026976                                                           15    9605
>NP_001165907
          Length = 1151

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKQEVVT 7
           TKQE++T
Sbjct: 279 TKQEIIT 285
>NP_476506
          Length = 1237

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 298 TKREVITAV 306
>NP_002628
          Length = 1223

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKQEVVT 7
           TKQE++T
Sbjct: 279 TKQEIIT 285
>NP_476505
          Length = 1036

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 97  TKREVITAV 105
>NP_004360
          Length = 3177

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 504 TKREVITAV 512
>NP_476508
          Length = 2971

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 298 TKREVITAV 306
>NP_001116142
          Length = 1210

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKQEVVT 7
           TKQE++T
Sbjct: 279 TKQEIIT 285
>NP_476507
          Length = 2570

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 97  TKREVITAV 105
>XP_006724724
          Length = 1164

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKQEVVT 7
           TKQE++T
Sbjct: 279 TKQEIIT 285
>XP_005246123
          Length = 2770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 97  TKREVITAV 105
>XP_005246122
          Length = 2977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 504 TKREVITAV 512
>XP_006712316
          Length = 3010

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV+T +
Sbjct: 504 TKREVITAV 512
>NP_003699
          Length = 317

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TKQ+ VT++
Sbjct: 126 TKQDFVTIL 134
>NP_000843
          Length = 210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KQEVVTV 8
          K+EVVTV
Sbjct: 30 KEEVVTV 36
>NP_640337
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           +KQEV+T +
Sbjct: 531 SKQEVITEV 539
>NP_001121187
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           +KQEV+T +
Sbjct: 531 SKQEVITEV 539
>XP_006715402
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           +KQEV+T +
Sbjct: 531 SKQEVITEV 539
>NP_001137292
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KQEVVT 7
           KQEVVT
Sbjct: 271 KQEVVT 276
>NP_001360
          Length = 4624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TKQEVVT 7
            TK+EV+T
Sbjct: 1130 TKKEVIT 1136
>NP_005229
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KQEVVT 7
           KQEVVT
Sbjct: 227 KQEVVT 232
>NP_001157017
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 272 TKEELYTVL 280
>NP_009178
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 351 TKEELYTVL 359
>NP_942583
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>NP_542117
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>NP_001157016
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>NP_001157018
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>NP_001157019
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>NP_055907
          Length = 3661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KQEVVTV 8
            KQE VTV
Sbjct: 2729 KQEAVTV 2735
>NP_005662
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKQEVVTV 8
           T +EVVTV
Sbjct: 187 TAEEVVTV 194
>NP_001269128
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKQEVVTV 8
           T +EVVTV
Sbjct: 146 TAEEVVTV 153
>NP_001269118
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKQEVVTV 8
           T +EVVTV
Sbjct: 150 TAEEVVTV 157
>NP_064710
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV TV+
Sbjct: 607 TKREVNTVL 615
>NP_000373
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QEVVTVI 9
          QEV+TV+
Sbjct: 59 QEVITVL 65
>NP_938020
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_006725374
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>XP_006725373
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 272 TKEELYTVL 280
>XP_006725372
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006725371
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 351 TKEELYTVL 359
>XP_006725370
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006725369
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006725368
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 424 TKEELYTVL 432
>XP_006725367
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006725366
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006725365
          Length = 1414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 451 TKEELYTVL 459
>XP_006725364
          Length = 1415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006724543
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_006724542
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_005274533
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_005274532
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_006724541
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_005274531
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 453 QEIITII 459
>XP_006724540
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_005274530
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QEVVTVI 9
           QE++T+I
Sbjct: 473 QEIITII 479
>XP_006721718
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 273 TKEELYTVL 281
>XP_006721717
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 272 TKEELYTVL 280
>XP_006721716
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_005257045
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 351 TKEELYTVL 359
>XP_005257043
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_005257042
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_006721715
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 424 TKEELYTVL 432
>XP_005257040
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_005257039
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_005257038
          Length = 1414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 451 TKEELYTVL 459
>XP_005257037
          Length = 1415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+E+ TV+
Sbjct: 452 TKEELYTVL 460
>XP_005255493
          Length = 959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV TV+
Sbjct: 540 TKREVNTVL 548
>XP_006721128
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV TV+
Sbjct: 540 TKREVNTVL 548
>XP_005255492
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKQEVVTVI 9
           TK+EV TV+
Sbjct: 607 TKREVNTVL 615
>XP_005255242
          Length = 3609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KQEVVTV 8
            KQE VTV
Sbjct: 2677 KQEAVTV 2683
>XP_005255241
          Length = 3637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KQEVVTV 8
            KQE VTV
Sbjct: 2705 KQEAVTV 2711
>XP_005255240
          Length = 3663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KQEVVTV 8
            KQE VTV
Sbjct: 2731 KQEAVTV 2737
>XP_005255239
          Length = 3689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KQEVVTV 8
            KQE VTV
Sbjct: 2757 KQEAVTV 2763
>XP_005271485
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KQEVVT 7
           KQEVVT
Sbjct: 204 KQEVVT 209
>XP_005248319
          Length = 4609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TKQEVVT 7
            TK+EV+T
Sbjct: 1115 TKKEVIT 1121
>NP_001026976
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QEVVTVI 9
          QEV+TV+
Sbjct: 59 QEVITVL 65
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.124    0.284 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,888
Number of extensions: 674
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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