Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     869
XP_006716142                                                           19     869
XP_005250088                                                           19     869
XP_006716141                                                           19     869
XP_005250085                                                           19     869
XP_006716140                                                           19     869
XP_005250084                                                           19     869
XP_005250083                                                           19     869
XP_005250082                                                           19     869
NP_114148                                                              17    3301
NP_001230075                                                           17    3301
NP_002524                                                              17    3301
NP_001230076                                                           17    3301
NP_996671                                                              17    3301
XP_006711841                                                           17    3301
XP_006711840                                                           17    3301
XP_006711837                                                           17    3301
XP_006711836                                                           17    3301
XP_006711835                                                           17    3301
NP_002212                                                              17    4312
NP_061869                                                              16    5631
NP_001136112                                                           16    5631
NP_001244025                                                           16    5631
NP_006183                                                              16    5631
XP_006722063                                                           16    5631
XP_006722061                                                           16    5631
XP_006722060                                                           16    5631
XP_005257605                                                           16    5631
XP_005257604                                                           16    5631
XP_006722059                                                           16    5631
NP_001265514                                                           16    7355
NP_001265515                                                           16    7355
NP_006578                                                              16    7355
NP_602296                                                              16    7355
NP_149043                                                              16    7355
NP_001155973                                                           16    7355
NP_001020014                                                           16    7355
NP_055903                                                              16    7355
NP_056009                                                              16    7355
NP_004609                                                              16    7355
XP_005256834                                                           16    7355
XP_005256833                                                           16    7355
XP_006719058                                                           16    7355
XP_005253778                                                           16    7355
XP_005253777                                                           16    7355
NP_001191742                                                           15    9605
NP_002517                                                              15    9605
NP_060678                                                              15    9605
NP_060115                                                              15    9605
NP_001177965                                                           15    9605
NP_001177964                                                           15    9605
NP_001257819                                                           15    9605
NP_001165268                                                           15    9605
NP_001165266                                                           15    9605
NP_001165267                                                           15    9605
NP_001165270                                                           15    9605
NP_001165269                                                           15    9605
XP_006716609                                                           15    9605
XP_006716608                                                           15    9605
XP_005245359                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2008 TKPSPRADV 2016
>XP_006716142
          Length = 4927

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>XP_005250088
          Length = 4928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>XP_006716141
          Length = 4959

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>XP_005250085
          Length = 4979

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>XP_006716140
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>XP_005250084
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>XP_005250083
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2024 TKPSPRADV 2032
>XP_005250082
          Length = 4983

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            TKPS RADV
Sbjct: 2025 TKPSPRADV 2033
>NP_114148
          Length = 450

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TKPSLRADV 9
          TKP  R+D+
Sbjct: 49 TKPKFRSDI 57
>NP_001230075
          Length = 667

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 577 TKPPLDADV 585
>NP_002524
          Length = 856

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 766 TKPPLDADV 774
>NP_001230076
          Length = 765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 675 TKPPLDADV 683
>NP_996671
          Length = 750

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 660 TKPPLDADV 668
>XP_006711841
          Length = 592

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 502 TKPPLDADV 510
>XP_006711840
          Length = 640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 550 TKPPLDADV 558
>XP_006711837
          Length = 738

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 648 TKPPLDADV 656
>XP_006711836
          Length = 738

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 648 TKPPLDADV 656
>XP_006711835
          Length = 828

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           TKP L ADV
Sbjct: 766 TKPPLDADV 774
>NP_002212
          Length = 946

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KPSLRADV 9
           KPSLR D+
Sbjct: 762 KPSLRKDM 769
>NP_061869
          Length = 1690

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1104 SQPSLRAQV 1112
>NP_001136112
          Length = 1726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1101 SQPSLRAQV 1109
>NP_001244025
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KPSLRADV 9
           KP+L AD+
Sbjct: 342 KPALEADI 349
>NP_006183
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KPSLRADV 9
           KP+L AD+
Sbjct: 342 KPALEADI 349
>XP_006722063
          Length = 1923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1337 SQPSLRAQV 1345
>XP_006722061
          Length = 1913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1340 SQPSLRAQV 1348
>XP_006722060
          Length = 1915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1290 SQPSLRAQV 1298
>XP_005257605
          Length = 1926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1340 SQPSLRAQV 1348
>XP_005257604
          Length = 1962

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1337 SQPSLRAQV 1345
>XP_006722059
          Length = 1965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TKPSLRADV 9
            ++PSLRA V
Sbjct: 1340 SQPSLRAQV 1348
>NP_001265514
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KPSLRAD 8
          KP LRAD
Sbjct: 20 KPVLRAD 26
>NP_001265515
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KPSLRAD 8
          KP LRAD
Sbjct: 20 KPVLRAD 26
>NP_006578
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KPSLRAD 8
          KP LRAD
Sbjct: 20 KPVLRAD 26
>NP_602296
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KPSLRAD 8
           KPS RAD
Sbjct: 344 KPSSRAD 350
>NP_149043
          Length = 1018

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           T PS RA+V
Sbjct: 123 TNPSQRAEV 131
>NP_001155973
          Length = 1833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TKPSLRADV 9
            + PSLRA V
Sbjct: 1220 SSPSLRAQV 1228
>NP_001020014
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           + PSLRA V
Sbjct: 416 SSPSLRAQV 424
>NP_055903
          Length = 1723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TKPSLRADV 9
            + PSLRA V
Sbjct: 1110 SSPSLRAQV 1118
>NP_056009
          Length = 1006

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TKPSLRADV 9
           T PS RA+V
Sbjct: 123 TNPSQRAEV 131
>NP_004609
          Length = 1001

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKPSLRADV 9
           +KP LRA++
Sbjct: 580 SKPDLRAEL 588
>XP_005256834
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKPSLRADV 9
           +KP LRA++
Sbjct: 110 SKPDLRAEL 118
>XP_005256833
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKPSLRADV 9
           +KP LRA++
Sbjct: 485 SKPDLRAEL 493
>XP_006719058
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KPSLRAD 8
           KPS RAD
Sbjct: 310 KPSSRAD 316
>XP_005253778
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KPSLRAD 8
           KPS RAD
Sbjct: 344 KPSSRAD 350
>XP_005253777
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KPSLRAD 8
           KPS RAD
Sbjct: 344 KPSSRAD 350
>NP_001191742
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   PSLRADV 9
           PS++AD+
Sbjct: 318 PSIKADI 324
>NP_002517
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   PSLRADV 9
           PS++AD+
Sbjct: 318 PSIKADI 324
>NP_060678
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   PSLRADV 9
           PSL ADV
Sbjct: 213 PSLSADV 219
>NP_060115
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KPSLRADV 9
           KPSLR  +
Sbjct: 893 KPSLRTSI 900
>NP_001177965
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>NP_001177964
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>NP_001257819
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KPSLRADV 9
           KPSLR  +
Sbjct: 858 KPSLRTSI 865
>NP_001165268
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>NP_001165266
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>NP_001165267
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>NP_001165270
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>NP_001165269
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>XP_006716609
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>XP_006716608
          Length = 86

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TKPSLRA 7
          TKP LRA
Sbjct: 28 TKPILRA 34
>XP_005245359
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   PSLRADV 9
           PSL ADV
Sbjct: 213 PSLSADV 219
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.124    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 751,405
Number of extensions: 1149
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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