Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     509
NP_001035957                                                           20     509
XP_006721991                                                           20     509
XP_006721990                                                           20     509
XP_006721989                                                           20     509
XP_005258041                                                           20     509
XP_006721988                                                           20     509
XP_006721987                                                           20     509
XP_006721986                                                           20     509
XP_005258040                                                           20     509
XP_006721985                                                           20     509
NP_005575                                                              17    3301
NP_006430                                                              17    3301
NP_001239553                                                           15    9605
NP_001106272                                                           15    9605
NP_001106271                                                           15    9605
NP_066920                                                              15    9605
NP_073579                                                              15    9605
XP_006716153                                                           15    9605
XP_005250594                                                           15    9605
XP_005250593                                                           15    9605
XP_006716152                                                           15    9605
XP_005250591                                                           15    9605
XP_005264571                                                           15    9605
XP_005264570                                                           15    9605
XP_006712148                                                           15    9605
XP_006712147                                                           15    9605
XP_006712146                                                           15    9605
XP_006712145                                                           15    9605
XP_006712144                                                           15    9605
XP_006712143                                                           15    9605
XP_005264569                                                           15    9605
XP_006710602                                                           15    9605
XP_006710601                                                           15    9605
XP_006710598                                                           15    9605
XP_006710597                                                           15    9605
XP_006710596                                                           15    9605
XP_006710595                                                           15    9605
XP_006710594                                                           15    9605
XP_006710593                                                           15    9605
XP_006710592                                                           15    9605
XP_006710591                                                           15    9605
XP_006710590                                                           15    9605
XP_006710589                                                           15    9605
XP_006710588                                                           15    9605
XP_006710587                                                           15    9605
XP_006710586                                                           15    9605
XP_006710585                                                           15    9605
XP_005270755                                                           15    9605
XP_006710584                                                           15    9605
XP_005270754                                                           15    9605
XP_005270753                                                           15    9605
XP_006710583                                                           15    9605
XP_005270752                                                           15    9605
XP_006710582                                                           15    9605
XP_005270751                                                           15    9605
NP_001106273                                                           15    9605
>NP_000258
          Length = 2818

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 685 TKLEVALYM 693
>NP_001035957
          Length = 2839

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 685 TKLEVALYM 693
>XP_006721991
          Length = 1632

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 695 TKLEVALYM 703
>XP_006721990
          Length = 2823

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 695 TKLEVALYM 703
>XP_006721989
          Length = 2823

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 695 TKLEVALYM 703
>XP_005258041
          Length = 2836

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 685 TKLEVALYM 693
>XP_006721988
          Length = 2846

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 695 TKLEVALYM 703
>XP_006721987
          Length = 2849

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 695 TKLEVALYM 703
>XP_006721986
          Length = 2854

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 682 TKLEVALYM 690
>XP_005258040
          Length = 2857

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 685 TKLEVALYM 693
>XP_006721985
          Length = 2867

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKLEVVLYM 9
           TKLEV LYM
Sbjct: 695 TKLEVALYM 703
>NP_005575
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TKLEVVLYM 9
          T+ EVVLY+
Sbjct: 72 TEFEVVLYL 80
>NP_006430
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TKLEVVLYM 9
          T+ EVVLY+
Sbjct: 72 TEFEVVLYL 80
>NP_001239553
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 702 TKLEVII 708
>NP_001106272
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 697 TKLEVII 703
>NP_001106271
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 705 TKLEVII 711
>NP_066920
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 710 TKLEVII 716
>NP_073579
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LEVVLY 8
            LEVVLY
Sbjct: 1017 LEVVLY 1022
>XP_006716153
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LEVVLY 8
           LEVVLY
Sbjct: 336 LEVVLY 341
>XP_005250594
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LEVVLY 8
            LEVVLY
Sbjct: 1002 LEVVLY 1007
>XP_005250593
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LEVVLY 8
            LEVVLY
Sbjct: 1055 LEVVLY 1060
>XP_006716152
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LEVVLY 8
            LEVVLY
Sbjct: 1058 LEVVLY 1063
>XP_005250591
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LEVVLY 8
            LEVVLY
Sbjct: 1067 LEVVLY 1072
>XP_005264571
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 674 TKLEVII 680
>XP_005264570
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 704 TKLEVII 710
>XP_006712148
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712147
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712146
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712145
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712144
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712143
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 733 TKLEVII 739
>XP_005264569
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 740 TKLEVII 746
>XP_006710602
          Length = 7391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2920 TKIEIISHM 2928
>XP_006710601
          Length = 4720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710598
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2910 TKIEIISHM 2918
>XP_006710597
          Length = 7451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2920 TKIEIISHM 2928
>XP_006710596
          Length = 7512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2869 TKIEIISHM 2877
>XP_006710595
          Length = 7526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2883 TKIEIISHM 2891
>XP_006710594
          Length = 7528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2885 TKIEIISHM 2893
>XP_006710593
          Length = 7539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2896 TKIEIISHM 2904
>XP_006710592
          Length = 7544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2901 TKIEIISHM 2909
>XP_006710591
          Length = 7558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2915 TKIEIISHM 2923
>XP_006710590
          Length = 7563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2920 TKIEIISHM 2928
>XP_006710589
          Length = 7595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 2952 TKIEIISHM 2960
>XP_006710588
          Length = 7614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710587
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710586
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710585
          Length = 7657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_005270755
          Length = 7663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710584
          Length = 7686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_005270754
          Length = 7694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_005270753
          Length = 7700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710583
          Length = 7702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_005270752
          Length = 7717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_006710582
          Length = 7720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>XP_005270751
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    TKLEVVLYM 9
            TK+E++ +M
Sbjct: 3080 TKIEIISHM 3088
>NP_001106273
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TKLEVVL 7
           TKLEV++
Sbjct: 674 TKLEVII 680
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.140    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,443
Number of extensions: 380
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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