Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           19     665
NP_001257437                                                           19     665
NP_006281                                                              19     665
XP_006715618                                                           19     665
XP_005267176                                                           19     665
NP_892006                                                              17    2528
NP_149062                                                              17    2528
XP_006715488                                                           17    2528
XP_006715487                                                           17    2528
XP_006715486                                                           17    2528
XP_006715485                                                           17    2528
XP_006715484                                                           17    2528
XP_006715483                                                           17    2528
XP_006715482                                                           17    2528
XP_006715481                                                           17    2528
XP_006715480                                                           17    2528
XP_006715479                                                           17    2528
XP_006715478                                                           17    2528
XP_006715477                                                           17    2528
XP_006715476                                                           17    2528
XP_006715475                                                           17    2528
XP_006715474                                                           17    2528
XP_006715473                                                           17    2528
XP_006715472                                                           17    2528
XP_006715471                                                           17    2528
XP_006715470                                                           17    2528
NP_008864                                                              16    7355
NP_001073919                                                           16    7355
NP_001138775                                                           16    7355
NP_653287                                                              16    7355
NP_001035091                                                           16    7355
NP_112590                                                              16    7355
NP_004518                                                              16    7355
XP_006726250                                                           16    7355
XP_006726210                                                           16    7355
XP_006726112                                                           16    7355
XP_006726013                                                           16    7355
XP_006725925                                                           16    7355
XP_006725825                                                           16    7355
XP_006725698                                                           16    7355
XP_006719746                                                           16    7355
XP_005253685                                                           16    7355
XP_005253684                                                           16    7355
XP_006715596                                                           16    7355
XP_005267137                                                           16    7355
XP_006715595                                                           16    7355
XP_005267136                                                           16    7355
NP_001136407                                                           16    7355
NP_003950                                                              16    7355
NP_002408                                                              15    9605
NP_001139438                                                           15    9605
NP_064627                                                              15    9605
NP_001158307                                                           15    9605
NP_061952                                                              15    9605
NP_059142                                                              15    9605
XP_006724089                                                           15    9605
XP_006717927                                                           15    9605
XP_006713327                                                           15    9605
XP_005265385                                                           15    9605
NP_542984                                                              15    9605
>NP_001257436
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TKEQLRSSQ 9
           T+EQLRSSQ
Sbjct: 692 TEEQLRSSQ 700
>NP_001257437
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TKEQLRSSQ 9
           T+EQLRSSQ
Sbjct: 692 TEEQLRSSQ 700
>NP_006281
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TKEQLRSSQ 9
           T+EQLRSSQ
Sbjct: 692 TEEQLRSSQ 700
>XP_006715618
          Length = 577

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TKEQLRSSQ 9
           T+EQLRSSQ
Sbjct: 479 TEEQLRSSQ 487
>XP_005267176
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TKEQLRSSQ 9
           T+EQLRSSQ
Sbjct: 692 TEEQLRSSQ 700
>NP_892006
          Length = 8797

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2612 TKEKLRSCQ 2620
>NP_149062
          Length = 8749

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715488
          Length = 8721

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715487
          Length = 8744

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715486
          Length = 8758

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715485
          Length = 8793

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2566 TKEKLRSCQ 2574
>XP_006715484
          Length = 8794

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715483
          Length = 8795

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715482
          Length = 8797

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2612 TKEKLRSCQ 2620
>XP_006715481
          Length = 8799

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2572 TKEKLRSCQ 2580
>XP_006715480
          Length = 8799

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715479
          Length = 8804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715478
          Length = 8809

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715477
          Length = 8822

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2595 TKEKLRSCQ 2603
>XP_006715476
          Length = 8823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715475
          Length = 8827

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715474
          Length = 8829

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2602 TKEKLRSCQ 2610
>XP_006715473
          Length = 8832

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715472
          Length = 8839

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2612 TKEKLRSCQ 2620
>XP_006715471
          Length = 8842

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>XP_006715470
          Length = 8846

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TKEQLRSSQ 9
            TKE+LRS Q
Sbjct: 2619 TKEKLRSCQ 2627
>NP_008864
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TKEQLRSS 8
           TKEQ+R++
Sbjct: 537 TKEQIRTT 544
>NP_001073919
          Length = 828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TKEQLRS 7
           +KEQLRS
Sbjct: 556 SKEQLRS 562
>NP_001138775
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKEQLRSSQ 9
           TKE LRS Q
Sbjct: 135 TKEGLRSLQ 143
>NP_653287
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TKEQLRSSQ 9
           TKE LRS Q
Sbjct: 129 TKEGLRSLQ 137
>NP_001035091
          Length = 139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  TKEQLR 6
          TKEQLR
Sbjct: 64 TKEQLR 69
>NP_112590
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KEQLRSSQ 9
           KE+LRS Q
Sbjct: 120 KERLRSKQ 127
>NP_004518
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TKEQLR 6
           TKEQLR
Sbjct: 179 TKEQLR 184
>XP_006726250
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006726210
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006726112
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006726013
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006725925
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006725825
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006725698
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TKEQLRSSQ 9
          TKE LRS Q
Sbjct: 39 TKEGLRSLQ 47
>XP_006719746
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKEQLRSSQ 9
           ++EQ RSSQ
Sbjct: 573 SREQQRSSQ 581
>XP_005253685
          Length = 1061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKEQLRSSQ 9
           ++EQ RSSQ
Sbjct: 578 SREQQRSSQ 586
>XP_005253684
          Length = 1073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKEQLRSSQ 9
           ++EQ RSSQ
Sbjct: 590 SREQQRSSQ 598
>XP_006715596
          Length = 743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TKEQLRS 7
           +KEQLRS
Sbjct: 471 SKEQLRS 477
>XP_005267137
          Length = 828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TKEQLRS 7
           +KEQLRS
Sbjct: 556 SKEQLRS 562
>XP_006715595
          Length = 828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TKEQLRS 7
           +KEQLRS
Sbjct: 556 SKEQLRS 562
>XP_005267136
          Length = 828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TKEQLRS 7
           +KEQLRS
Sbjct: 556 SKEQLRS 562
>NP_001136407
          Length = 193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KEQLRSSQ 9
           KE+LRS Q
Sbjct: 120 KERLRSKQ 127
>NP_003950
          Length = 1068

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TKEQLRSSQ 9
           ++EQ RSSQ
Sbjct: 585 SREQQRSSQ 593
>NP_002408
          Length = 3256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    TKEQLRSS 8
            TK+QL++S
Sbjct: 1021 TKQQLKAS 1028
>NP_001139438
          Length = 2896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TKEQLRSS 8
           TK+QL++S
Sbjct: 661 TKQQLKAS 668
>NP_064627
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    KEQLRS 7
            KEQLRS
Sbjct: 1305 KEQLRS 1310
>NP_001158307
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKEQLRSS 8
           T+E LRSS
Sbjct: 613 TEENLRSS 620
>NP_061952
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKEQLRSS 8
           T+E LRSS
Sbjct: 613 TEENLRSS 620
>NP_059142
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TKEQLRS 7
           TKE LRS
Sbjct: 195 TKENLRS 201
>XP_006724089
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TKEQLRS 7
           TKE LRS
Sbjct: 195 TKENLRS 201
>XP_006717927
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TKEQLRSS 8
           TK+QL++S
Sbjct: 171 TKQQLKAS 178
>XP_006713327
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KEQLRS 7
           KEQLRS
Sbjct: 940 KEQLRS 945
>XP_005265385
          Length = 1291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    KEQLRS 7
            KEQLRS
Sbjct: 1208 KEQLRS 1213
>NP_542984
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TKEQLRS 7
           TKE LRS
Sbjct: 195 TKENLRS 201
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289    0.101    0.220 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,315
Number of extensions: 595
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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