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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              20     509
NP_055585                                                              16    5631
NP_982272                                                              16    5631
NP_001116244                                                           16    5631
NP_001177387                                                           16    5631
NP_001180465                                                           16    5631
NP_065694                                                              16    5631
XP_005268683                                                           16    5631
XP_005268682                                                           16    5631
NP_001231892                                                           16    7355
NP_065955                                                              16    7355
NP_001154826                                                           16    7355
NP_055523                                                              16    7355
NP_777576                                                              16    7355
XP_006723364                                                           16    7355
XP_005259166                                                           16    7355
XP_005259165                                                           16    7355
XP_005259164                                                           16    7355
XP_006719769                                                           16    7355
XP_006718432                                                           16    7355
XP_006718430                                                           16    7355
XP_006718429                                                           16    7355
XP_006718427                                                           16    7355
NP_002607                                                              15    9605
NP_061027                                                              15    9605
NP_065863                                                              15    9605
XP_005260057                                                           15    9605
XP_006722867                                                           15    9605
XP_006722866                                                           15    9605
XP_006722865                                                           15    9605
XP_005260058                                                           15    9605
XP_005256747                                                           15    9605
XP_005256746                                                           15    9605

>NP_002430
          Length = 1137

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TKAVSRLHS 9
           TKAVSR HS
Sbjct: 774 TKAVSRFHS 782



>NP_055585
          Length = 836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KAVSRLH 8
           +AVSRLH
Sbjct: 152 QAVSRLH 158



>NP_982272
          Length = 2099

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KAVS +HS
Sbjct: 1184 KAVSAIHS 1191



>NP_001116244
          Length = 1192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KAVSRLH 8
           +AVSRLH
Sbjct: 488 QAVSRLH 494



>NP_001177387
          Length = 1999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KAVS +HS
Sbjct: 1084 KAVSAIHS 1091



>NP_001180465
          Length = 2031

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KAVS +HS
Sbjct: 1116 KAVSAIHS 1123



>NP_065694
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAVSRLH 8
           KAV RLH
Sbjct: 220 KAVERLH 226



>XP_005268683
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KAVSRLH 8
           +AVSRLH
Sbjct: 152 QAVSRLH 158



>XP_005268682
          Length = 1172

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KAVSRLH 8
           +AVSRLH
Sbjct: 488 QAVSRLH 494



>NP_001231892
          Length = 2488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VSRLHS 9
            VSRLHS
Sbjct: 1645 VSRLHS 1650



>NP_065955
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  TKAVSRLHS 9
          T+AV+++H+
Sbjct: 31 TRAVNKIHA 39



>NP_001154826
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  TKAVSRLHS 9
          T+AV+++H+
Sbjct: 31 TRAVNKIHA 39



>NP_055523
          Length = 2209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KA+S +HS
Sbjct: 2000 KAISSIHS 2007



>NP_777576
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AVSRLH 8
           AVSRLH
Sbjct: 627 AVSRLH 632



>XP_006723364
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  TKAVSRLHS 9
          T+AV+++H+
Sbjct: 31 TRAVNKIHA 39



>XP_005259166
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  TKAVSRLHS 9
          T+AV+++H+
Sbjct: 31 TRAVNKIHA 39



>XP_005259165
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  TKAVSRLHS 9
          T+AV+++H+
Sbjct: 31 TRAVNKIHA 39



>XP_005259164
          Length = 754

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  TKAVSRLHS 9
          T+AV+++H+
Sbjct: 31 TRAVNKIHA 39



>XP_006719769
          Length = 2209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KA+S +HS
Sbjct: 2000 KAISSIHS 2007



>XP_006718432
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VSRLHS 9
           VSRLHS
Sbjct: 621 VSRLHS 626



>XP_006718430
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VSRLHS 9
           VSRLHS
Sbjct: 708 VSRLHS 713



>XP_006718429
          Length = 2416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VSRLHS 9
            VSRLHS
Sbjct: 1573 VSRLHS 1578



>XP_006718427
          Length = 2465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VSRLHS 9
            VSRLHS
Sbjct: 1622 VSRLHS 1627



>NP_002607
          Length = 1290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TKAVSRLHS 9
           TKAV  LH+
Sbjct: 779 TKAVLSLHT 787



>NP_061027
          Length = 4599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TKAVSRLH 8
            TK++SR H
Sbjct: 3234 TKSLSRAH 3241



>NP_065863
          Length = 2047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KA+S +HS
Sbjct: 1134 KAISAVHS 1141



>XP_005260057
          Length = 2113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KA+S +HS
Sbjct: 1200 KAISAVHS 1207



>XP_006722867
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KAVSRLHS 9
           KA+S +HS
Sbjct: 246 KAISAVHS 253



>XP_006722866
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KAVSRLHS 9
           KA+S +HS
Sbjct: 865 KAISAVHS 872



>XP_006722865
          Length = 2078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KA+S +HS
Sbjct: 1165 KAISAVHS 1172



>XP_005260058
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KAVSRLHS 9
            KA+S +HS
Sbjct: 1169 KAISAVHS 1176



>XP_005256747
          Length = 1230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TKAVSRLHS 9
           TKAV  LH+
Sbjct: 719 TKAVLSLHT 727



>XP_005256746
          Length = 1290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TKAVSRLHS 9
           TKAV  LH+
Sbjct: 779 TKAVLSLHT 787



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.113    0.286 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,322
Number of extensions: 465
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)