Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001104537                                                           16    7355
NP_001096                                                              16    7355
NP_001005340                                                           16    7355
NP_002501                                                              16    7355
XP_005249635                                                           16    7355
XP_006712888                                                           16    7355
XP_005246996                                                           16    7355
XP_005246997                                                           16    7355
NP_002323                                                              15    9605
NP_006244                                                              15    9605
XP_005253966                                                           15    9605
>NP_001104537
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 IVEGVMVL 9
         +V+GVM+L
Sbjct: 1 MVDGVMIL 8
>NP_001096
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 IVEGVMVL 9
         +V+GVM+L
Sbjct: 1 MVDGVMIL 8
>NP_001005340
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIVEGVM 7
           TIVEG++
Sbjct: 382 TIVEGIL 388
>NP_002501
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIVEGVM 7
           TIVEG++
Sbjct: 370 TIVEGIL 376
>XP_005249635
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIVEGVM 7
           TIVEG++
Sbjct: 382 TIVEGIL 388
>XP_006712888
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 IVEGVMVL 9
         +V+GVM+L
Sbjct: 1 MVDGVMIL 8
>XP_005246996
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 IVEGVMVL 9
         +V+GVM+L
Sbjct: 1 MVDGVMIL 8
>XP_005246997
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 IVEGVMVL 9
         +V+GVM+L
Sbjct: 1 MVDGVMIL 8
>NP_002323
          Length = 4544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   TIVEGVMV 8
           TI++G+++
Sbjct: 403 TIIQGILI 410
>NP_006244
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TIVEGVMVL 9
           +I +GVMVL
Sbjct: 243 SIKDGVMVL 251
>XP_005253966
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TIVEGVMVL 9
           +I +GVMVL
Sbjct: 243 SIKDGVMVL 251
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.147    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,786
Number of extensions: 224
Number of successful extensions: 11
Number of sequences better than 10000.0: 11
Number of HSP's gapped: 11
Number of HSP's successfully gapped: 11
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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