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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              18    1135
NP_001087241                                                           18    1135
XP_006714101                                                           18    1135
XP_005265799                                                           18    1135
XP_005265798                                                           18    1135
XP_005265797                                                           18    1135
NP_001186794                                                           17    4312
NP_001186795                                                           17    4312
NP_078980                                                              17    4312
XP_005260812                                                           17    4312
XP_006723651                                                           17    4312
XP_005260811                                                           17    4312
XP_005260810                                                           17    4312
XP_005260809                                                           17    4312
XP_005260808                                                           17    4312
XP_005260807                                                           17    4312
NP_001180360                                                           16    7355
NP_057051                                                              16    7355
NP_036543                                                              16    7355
XP_005270795                                                           16    7355
NP_002474                                                              15    9605
NP_001008744                                                           15    9605
NP_060789                                                              15    9605
XP_006720261                                                           15    9605
XP_005267905                                                           15    9605
XP_005267904                                                           15    9605
XP_006720260                                                           15    9605
NP_001139669                                                           15    9605

>NP_000213
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TISSARVN 8
           TISSARVN
Sbjct: 276 TISSARVN 283



>NP_001087241
          Length = 972

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TISSARVN 8
           TISSARVN
Sbjct: 276 TISSARVN 283



>XP_006714101
          Length = 526

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TISSARVN 8
           TISSARVN
Sbjct: 277 TISSARVN 284



>XP_005265799
          Length = 973

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TISSARVN 8
           TISSARVN
Sbjct: 277 TISSARVN 284



>XP_005265798
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TISSARVN 8
           TISSARVN
Sbjct: 277 TISSARVN 284



>XP_005265797
          Length = 977

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   TISSARVN 8
           TISSARVN
Sbjct: 277 TISSARVN 284



>NP_001186794
          Length = 1266

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>NP_001186795
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>NP_078980
          Length = 1317

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_005260812
          Length = 1277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_006723651
          Length = 1287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_005260811
          Length = 1298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_005260810
          Length = 1328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_005260809
          Length = 1832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_005260808
          Length = 1872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>XP_005260807
          Length = 1883

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS A VNY
Sbjct: 334 TISPADVNY 342



>NP_001180360
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA +NY
Sbjct: 492 VSSAELNY 499



>NP_057051
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA +NY
Sbjct: 492 VSSAELNY 499



>NP_036543
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA +NY
Sbjct: 437 VSSAELNY 444



>XP_005270795
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA +NY
Sbjct: 468 VSSAELNY 475



>NP_002474
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TISSARVNY 9
           TIS ++ NY
Sbjct: 241 TISPSKANY 249



>NP_001008744
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA+ NY
Sbjct: 197 VSSAQFNY 204



>NP_060789
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA+ NY
Sbjct: 197 VSSAQFNY 204



>XP_006720261
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA+ NY
Sbjct: 197 VSSAQFNY 204



>XP_005267905
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA+ NY
Sbjct: 197 VSSAQFNY 204



>XP_005267904
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA+ NY
Sbjct: 197 VSSAQFNY 204



>XP_006720260
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ISSARVNY 9
           +SSA+ NY
Sbjct: 197 VSSAQFNY 204



>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ISSARVNY 9
            ISS ++NY
Sbjct: 2939 ISSQQINY 2946



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.117    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 279,722
Number of extensions: 346
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)