Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001265546                                                           17    2528
NP_001265545                                                           17    2528
NP_004327                                                              17    2528
NP_005553                                                              17    4312
NP_061486                                                              17    4312
XP_006711379                                                           17    4312
XP_005245207                                                           17    4312
NP_000205                                                              15    9605
NP_004095                                                              15    9605
NP_478066                                                              15    9605
NP_001272369                                                           15    9605
NP_689969                                                              15    9605
NP_001272368                                                           15    9605
NP_001124162                                                           15    9605
NP_056306                                                              15    9605
NP_116259                                                              15    9605
NP_077816                                                              15    9605
NP_612457                                                              15    9605
NP_003449                                                              15    9605
NP_055987                                                              15    9605
XP_006724087                                                           15    9605
XP_006720682                                                           15    9605
XP_005268318                                                           15    9605
XP_006715515                                                           15    9605
XP_006715514                                                           15    9605
XP_006715513                                                           15    9605
XP_005266974                                                           15    9605
XP_005266973                                                           15    9605
XP_005266972                                                           15    9605
XP_005266971                                                           15    9605
XP_005266970                                                           15    9605
XP_005266969                                                           15    9605
XP_006715384                                                           15    9605
XP_005248335                                                           15    9605
XP_006714526                                                           15    9605
XP_006713443                                                           15    9605
XP_005245087                                                           15    9605
XP_005245086                                                           15    9605
XP_005245085                                                           15    9605
XP_005245084                                                           15    9605
XP_006711302                                                           15    9605
XP_005245083                                                           15    9605
XP_005245082                                                           15    9605
XP_005245081                                                           15    9605
XP_005245080                                                           15    9605
XP_005245079                                                           15    9605
XP_005245077                                                           15    9605
XP_005245076                                                           15    9605
XP_006711301                                                           15    9605
XP_005245075                                                           15    9605
XP_005245074                                                           15    9605
XP_005245073                                                           15    9605
XP_005245072                                                           15    9605
>NP_001265546
          Length = 1028

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TISSAEYSI 9
           TIS +EYS+
Sbjct: 213 TISKSEYSV 221
>NP_001265545
          Length = 1065

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TISSAEYSI 9
           TIS +EYS+
Sbjct: 193 TISKSEYSV 201
>NP_004327
          Length = 1085

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TISSAEYSI 9
           TIS +EYS+
Sbjct: 213 TISKSEYSV 221
>NP_005553
          Length = 1193

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSAEYSI 9
           SSAEYS+
Sbjct: 198 SSAEYSV 204
>NP_061486
          Length = 1111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSAEYSI 9
           SSAEYS+
Sbjct: 198 SSAEYSV 204
>XP_006711379
          Length = 1208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSAEYSI 9
           SSAEYS+
Sbjct: 261 SSAEYSV 267
>XP_005245207
          Length = 1256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSAEYSI 9
           SSAEYS+
Sbjct: 261 SSAEYSV 267
>NP_000205
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SAEYSI 9
           SAEYSI
Sbjct: 993 SAEYSI 998
>NP_004095
          Length = 2511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SSAEYSI 9
           SSAEY++
Sbjct: 730 SSAEYNV 736
>NP_478066
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ISSAEYSI 9
          +SSA YSI
Sbjct: 37 LSSAAYSI 44
>NP_001272369
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS +YS
Sbjct: 416 TVSSLDYS 423
>NP_689969
          Length = 1708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS +YS
Sbjct: 701 TVSSLDYS 708
>NP_001272368
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS +YS
Sbjct: 701 TVSSLDYS 708
>NP_001124162
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TISSAEY 7
           T+SS+EY
Sbjct: 613 TLSSSEY 619
>NP_056306
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 530 TVSSSSYS 537
>NP_116259
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 530 TVSSSSYS 537
>NP_077816
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TISSAEYS 8
           T+S  EYS
Sbjct: 443 TVSGVEYS 450
>NP_612457
          Length = 99

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  TISSAEYS 8
          TIS  EYS
Sbjct: 86 TISKLEYS 93
>NP_003449
          Length = 3926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    SSAEYS 8
            SSAEYS
Sbjct: 3701 SSAEYS 3706
>NP_055987
          Length = 2817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2173 SVSSAEY 2179
>XP_006724087
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ISSAEYSI 9
          +SSA YSI
Sbjct: 37 LSSAAYSI 44
>XP_006720682
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TISSAEYS 8
           T+S  EYS
Sbjct: 443 TVSGVEYS 450
>XP_005268318
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TISSAEYS 8
           T+S  EYS
Sbjct: 443 TVSGVEYS 450
>XP_006715515
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 435 TVSSSSYS 442
>XP_006715514
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 435 TVSSSSYS 442
>XP_006715513
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 435 TVSSSSYS 442
>XP_005266974
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 530 TVSSSSYS 537
>XP_005266973
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 530 TVSSSSYS 537
>XP_005266972
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 530 TVSSSSYS 537
>XP_005266971
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 575 TVSSSSYS 582
>XP_005266970
          Length = 868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 593 TVSSSSYS 600
>XP_005266969
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS+ YS
Sbjct: 593 TVSSSSYS 600
>XP_006715384
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TISSAEY 7
           T+SS+EY
Sbjct: 596 TLSSSEY 602
>XP_005248335
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS +YS
Sbjct: 416 TVSSLDYS 423
>XP_006714526
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TISSAEYS 8
           T+SS +YS
Sbjct: 701 TVSSLDYS 708
>XP_006713443
          Length = 3970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    SSAEYS 8
            SSAEYS
Sbjct: 3745 SSAEYS 3750
>XP_005245087
          Length = 2708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245086
          Length = 2714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245085
          Length = 2718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245084
          Length = 2719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_006711302
          Length = 2754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245083
          Length = 2774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245082
          Length = 2779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245081
          Length = 2819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245080
          Length = 2824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245079
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245077
          Length = 2858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245076
          Length = 2869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_006711301
          Length = 2896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2173 SVSSAEY 2179
>XP_005245075
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2170 SVSSAEY 2176
>XP_005245074
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
>XP_005245073
          Length = 2901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2173 SVSSAEY 2179
>XP_005245072
          Length = 2903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    TISSAEY 7
            ++SSAEY
Sbjct: 2175 SVSSAEY 2181
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.110    0.249 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,337
Number of extensions: 1408
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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