Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000305                                                              19     665
XP_006717989                                                           19     665
NP_005415                                                              18    1935
NP_001240286                                                           18    1935
XP_006710932                                                           18    1935
XP_005271220                                                           18    1935
NP_001171886                                                           17    3301
NP_115513                                                              17    3301
NP_001171887                                                           17    3301
XP_006713405                                                           17    3301
XP_006713404                                                           17    3301
NP_005520                                                              17    4312
NP_065385                                                              17    4312
XP_005245920                                                           17    4312
XP_006710660                                                           17    4312
XP_006710659                                                           17    4312
XP_006710658                                                           17    4312
XP_006710657                                                           17    4312
NP_110437                                                              16    5631
NP_001139021                                                           16    5631
XP_005258332                                                           16    5631
NP_005916                                                              16    5631
NP_000811                                                              16    7355
NP_001137417                                                           16    7355
NP_001137418                                                           16    7355
NP_001273675                                                           16    7355
NP_116228                                                              16    7355
NP_001273676                                                           16    7355
NP_079084                                                              16    7355
XP_006721609                                                           16    7355
XP_006719931                                                           16    7355
NP_036525                                                              16    7355
NP_849151                                                              16    7355
NP_055448                                                              16    7355
NP_115497                                                              15    9605
NP_055990                                                              15    9605
NP_001193976                                                           15    9605
NP_647537                                                              15    9605
NP_647538                                                              15    9605
NP_055553                                                              15    9605
NP_005269                                                              15    9605
NP_001001996                                                           15    9605
NP_001001995                                                           15    9605
NP_001001994                                                           15    9605
XP_005274547                                                           15    9605
XP_005274546                                                           15    9605
XP_005260918                                                           15    9605
XP_005260917                                                           15    9605
XP_005257924                                                           15    9605
XP_005257923                                                           15    9605
XP_005257922                                                           15    9605
XP_005257921                                                           15    9605
XP_006722263                                                           15    9605
XP_005257920                                                           15    9605
XP_005253668                                                           15    9605
XP_005253667                                                           15    9605
XP_005253666                                                           15    9605
XP_006716674                                                           15    9605
XP_005265050                                                           15    9605
XP_005265049                                                           15    9605
XP_006713135                                                           15    9605
NP_076417                                                              15    9605
>NP_000305
          Length = 403

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILMFSGGT 9
           TI MFSGGT
Sbjct: 202 TIPMFSGGT 210
>XP_006717989
          Length = 388

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILMFSGGT 9
           TI MFSGGT
Sbjct: 187 TIPMFSGGT 195
>NP_005415
          Length = 1138

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           TIL FS GT
Sbjct: 807 TILQFSSGT 815
>NP_001240286
          Length = 1093

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           TIL FS GT
Sbjct: 762 TILQFSSGT 770
>XP_006710932
          Length = 783

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           TIL FS GT
Sbjct: 452 TILQFSSGT 460
>XP_005271220
          Length = 1095

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           TIL FS GT
Sbjct: 764 TILQFSSGT 772
>NP_001171886
          Length = 782

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           ILMF+GG
Sbjct: 661 ILMFAGG 667
>NP_115513
          Length = 904

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           ILMF+GG
Sbjct: 783 ILMFAGG 789
>NP_001171887
          Length = 782

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           ILMF+GG
Sbjct: 661 ILMFAGG 667
>XP_006713405
          Length = 947

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           ILMF+GG
Sbjct: 783 ILMFAGG 789
>XP_006713404
          Length = 947

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           ILMF+GG
Sbjct: 783 ILMFAGG 789
>NP_005520
          Length = 4391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILMFSGG 8
            +L+FSGG
Sbjct: 3965 VLLFSGG 3971
>NP_065385
          Length = 731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           +L+FSGG
Sbjct: 210 VLLFSGG 216
>XP_005245920
          Length = 4392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILMFSGG 8
            +L+FSGG
Sbjct: 3966 VLLFSGG 3972
>XP_006710660
          Length = 4397

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILMFSGG 8
            +L+FSGG
Sbjct: 3971 VLLFSGG 3977
>XP_006710659
          Length = 4556

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILMFSGG 8
            +L+FSGG
Sbjct: 4130 VLLFSGG 4136
>XP_006710658
          Length = 4563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILMFSGG 8
            +L+FSGG
Sbjct: 4137 VLLFSGG 4143
>XP_006710657
          Length = 4579

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILMFSGG 8
            +L+FSGG
Sbjct: 4153 VLLFSGG 4159
>NP_110437
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILMFSGG 8
           T+L+F GG
Sbjct: 398 TLLLFRGG 405
>NP_001139021
          Length = 324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILMFSGG 8
           T+L+F GG
Sbjct: 290 TLLLFRGG 297
>XP_005258332
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+ +FS GT
Sbjct: 541 TVALFSNGT 549
>NP_005916
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+ +FS GT
Sbjct: 541 TVALFSNGT 549
>NP_000811
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           IL+F+GG
Sbjct: 333 ILLFAGG 339
>NP_001137417
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILMFSGG 8
          IL+F+GG
Sbjct: 60 ILLFAGG 66
>NP_001137418
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILMFSGG 8
          IL+F+GG
Sbjct: 34 ILLFAGG 40
>NP_001273675
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MFSGGT 9
           M+SGGT
Sbjct: 412 MYSGGT 417
>NP_116228
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILMFSGGT 9
           +L+FSG T
Sbjct: 351 LLLFSGAT 358
>NP_001273676
          Length = 489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MFSGGT 9
           M+SGGT
Sbjct: 267 MYSGGT 272
>NP_079084
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MFSGGT 9
           M+SGGT
Sbjct: 397 MYSGGT 402
>XP_006721609
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LMFSGG 8
           +MFSGG
Sbjct: 424 IMFSGG 429
>XP_006719931
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MFSGGT 9
           M+SGGT
Sbjct: 286 MYSGGT 291
>NP_036525
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LMFSGG 8
           +MFSGG
Sbjct: 424 IMFSGG 429
>NP_849151
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   TILMFSGG 8
           ++++FSGG
Sbjct: 123 SVMVFSGG 130
>NP_055448
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILMFSGGT 9
           ILMF+G T
Sbjct: 888 ILMFTGET 895
>NP_115497
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ILMFSGG 8
           +L+F+GG
Sbjct: 304 VLLFNGG 310
>NP_055990
          Length = 2754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    LMFSGG 8
            L+FSGG
Sbjct: 2473 LLFSGG 2478
>NP_001193976
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+L+F G T
Sbjct: 449 TMLVFGGNT 457
>NP_647537
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+L+F G T
Sbjct: 565 TMLVFGGNT 573
>NP_647538
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+L+F G T
Sbjct: 565 TMLVFGGNT 573
>NP_055553
          Length = 1356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 431 TVLFFSG 437
>NP_005269
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TILMFSG 7
          TIL FSG
Sbjct: 41 TILCFSG 47
>NP_001001996
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TILMFSG 7
          TIL FSG
Sbjct: 81 TILCFSG 87
>NP_001001995
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TILMFSG 7
          TIL FSG
Sbjct: 81 TILCFSG 87
>NP_001001994
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TILMFSG 7
          TIL FSG
Sbjct: 22 TILCFSG 28
>XP_005274547
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TILMFSG 7
          TIL FSG
Sbjct: 22 TILCFSG 28
>XP_005274546
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TILMFSG 7
          TIL FSG
Sbjct: 41 TILCFSG 47
>XP_005260918
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+L+F G T
Sbjct: 565 TMLVFGGNT 573
>XP_005260917
          Length = 1289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T+L+F G T
Sbjct: 565 TMLVFGGNT 573
>XP_005257924
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 163 TVLFFSG 169
>XP_005257923
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 172 TVLFFSG 178
>XP_005257922
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 441 TVLFFSG 447
>XP_005257921
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 441 TVLFFSG 447
>XP_006722263
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 431 TVLFFSG 437
>XP_005257920
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TILMFSG 7
           T+L FSG
Sbjct: 431 TVLFFSG 437
>XP_005253668
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LMFSGGT 9
           +MFS GT
Sbjct: 287 IMFSSGT 293
>XP_005253667
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LMFSGGT 9
           +MFS GT
Sbjct: 287 IMFSSGT 293
>XP_005253666
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LMFSGGT 9
           +MFS GT
Sbjct: 287 IMFSSGT 293
>XP_006716674
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILMFSGGT 9
           T L+F GG+
Sbjct: 823 TALVFGGGS 831
>XP_005265050
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    LMFSGG 8
            L+FSGG
Sbjct: 1297 LLFSGG 1302
>XP_005265049
          Length = 2720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    LMFSGG 8
            L+FSGG
Sbjct: 2439 LLFSGG 2444
>XP_006713135
          Length = 2727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    LMFSGG 8
            L+FSGG
Sbjct: 2446 LLFSGG 2451
>NP_076417
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LMFSGGT 9
           +MFS GT
Sbjct: 287 IMFSSGT 293
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.143    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 664,409
Number of extensions: 873
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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