Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_570711                                                              18    1935
NP_570712                                                              18    1935
NP_570714                                                              18    1935
NP_570713                                                              18    1935
NP_570716                                                              18    1935
NP_000235                                                              18    1935
NP_570715                                                              18    1935
XP_006718620                                                           18    1935
XP_005274059                                                           18    1935
XP_005274060                                                           18    1935
XP_005274058                                                           18    1935
NP_056327                                                              17    4312
XP_006713163                                                           17    4312
NP_569118                                                              16    5631
NP_932065                                                              16    5631
NP_932064                                                              16    5631
XP_005254562                                                           16    5631
XP_006720650                                                           16    5631
XP_005254559                                                           16    5631
XP_006720649                                                           16    5631
XP_005254557                                                           16    5631
XP_006713938                                                           16    5631
NP_060213                                                              16    5631
NP_001326                                                              16    7355
NP_006633                                                              15    9605
NP_002147                                                              15    9605
NP_955472                                                              15    9605
NP_599152                                                              15    9605
NP_443166                                                              15    9605
NP_061923                                                              15    9605
XP_006725036                                                           15    9605
XP_006725035                                                           15    9605
XP_006725031                                                           15    9605
XP_006725030                                                           15    9605
XP_006725027                                                           15    9605
XP_005263134                                                           15    9605
XP_006714303                                                           15    9605
XP_005263133                                                           15    9605
XP_005263132                                                           15    9605
XP_005263131                                                           15    9605
XP_005263130                                                           15    9605
XP_005246575                                                           15    9605
XP_005273080                                                           15    9605
XP_006711793                                                           15    9605
XP_005273073                                                           15    9605
XP_006711792                                                           15    9605
XP_006711790                                                           15    9605
XP_006711207                                                           15    9605
>NP_570711
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 150 TKLDSSGVA 158
>NP_570712
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 155 TKLDSSGVA 163
>NP_570714
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 155 TKLDSSGVA 163
>NP_570713
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 155 TKLDSSGVA 163
>NP_570716
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 155 TKLDSSGVA 163
>NP_000235
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 155 TKLDSSGVA 163
>NP_570715
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 155 TKLDSSGVA 163
>XP_006718620
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 150 TKLDSSGVA 158
>XP_005274059
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 150 TKLDSSGVA 158
>XP_005274060
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 150 TKLDSSGVA 158
>XP_005274058
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TILDSSGVA 9
           T LDSSGVA
Sbjct: 150 TKLDSSGVA 158
>NP_056327
          Length = 4265

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILDSSGV 8
           +LDSSGV
Sbjct: 664 VLDSSGV 670
>XP_006713163
          Length = 4265

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILDSSGV 8
           +LDSSGV
Sbjct: 664 VLDSSGV 670
>NP_569118
          Length = 882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 603 TILDSAG 609
>NP_932065
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 619 TILDSAG 625
>NP_932064
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 619 TILDSAG 625
>XP_005254562
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 200 TILDSAG 206
>XP_006720650
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 619 TILDSAG 625
>XP_005254559
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 619 TILDSAG 625
>XP_006720649
          Length = 855

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 576 TILDSAG 582
>XP_005254557
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 619 TILDSAG 625
>XP_006713938
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TILDSSGVA 9
          T+LD SGV+
Sbjct: 41 TLLDVSGVS 49
>NP_060213
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           TILDS+G
Sbjct: 603 TILDSAG 609
>NP_001326
          Length = 376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TILDSSGVA 9
           T+L++SG+A
Sbjct: 202 TVLNNSGLA 210
>NP_006633
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 177 TLLDASG 183
>NP_002147
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDSSGVA 9
           +LD++GVA
Sbjct: 529 LLDAAGVA 536
>NP_955472
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDSSGVA 9
           +LD++GVA
Sbjct: 529 LLDAAGVA 536
>NP_599152
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDSSGVA 9
           ILD SGV+
Sbjct: 666 ILDMSGVS 673
>NP_443166
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDSSGVA 9
           ILD SGV+
Sbjct: 666 ILDMSGVS 673
>NP_061923
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 711 TVMDISGV 718
>XP_006725036
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 177 TLLDASG 183
>XP_006725035
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 187 TLLDASG 193
>XP_006725031
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TILDSSG 7
          T+LD+SG
Sbjct: 79 TLLDASG 85
>XP_006725030
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 187 TLLDASG 193
>XP_006725027
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 187 TLLDASG 193
>XP_005263134
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 711 TVMDISGV 718
>XP_006714303
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 595 TVMDISGV 602
>XP_005263133
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 660 TVMDISGV 667
>XP_005263132
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 661 TVMDISGV 668
>XP_005263131
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 711 TVMDISGV 718
>XP_005263130
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TILDSSGV 8
           T++D SGV
Sbjct: 711 TVMDISGV 718
>XP_005246575
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDSSGVA 9
           +LD++GVA
Sbjct: 529 LLDAAGVA 536
>XP_005273080
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 177 TLLDASG 183
>XP_006711793
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 187 TLLDASG 193
>XP_005273073
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TILDSSG 7
          T+LD+SG
Sbjct: 79 TLLDASG 85
>XP_006711792
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 187 TLLDASG 193
>XP_006711790
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILDSSG 7
           T+LD+SG
Sbjct: 187 TLLDASG 193
>XP_006711207
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDSSGVA 9
           ILD SGV+
Sbjct: 666 ILDMSGVS 673
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.124    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,231
Number of extensions: 778
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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