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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
XP_005266703                                                           19     665
NP_055059                                                              17    2528
NP_006006                                                              17    4312
NP_002448                                                              17    4312
NP_001245258                                                           16    5631
NP_001245260                                                           16    5631
NP_071361                                                              16    5631
NP_001245259                                                           16    5631
NP_818932                                                              16    5631
NP_036288                                                              16    5631
XP_005260382                                                           16    5631
XP_005260381                                                           16    5631
XP_006723804                                                           16    5631
XP_005260380                                                           16    5631
XP_006723803                                                           16    5631
XP_005260379                                                           16    5631
XP_005260378                                                           16    5631
XP_005260377                                                           16    5631
XP_006723802                                                           16    5631
XP_005260376                                                           16    5631
XP_006723801                                                           16    5631
XP_006723800                                                           16    5631
XP_006723799                                                           16    5631
XP_006723798                                                           16    5631
NP_060128                                                              16    7355
XP_005267827                                                           16    7355
XP_005267826                                                           16    7355
NP_055690                                                              15    9605
NP_009165                                                              15    9605
NP_001268356                                                           15    9605
NP_001268354                                                           15    9605
NP_061980                                                              15    9605

>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TIATEVRPA 9
            TIATEV PA
Sbjct: 1012 TIATEVHPA 1020



>XP_005266703
          Length = 1501

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TIATEVRPA 9
           TIATEV PA
Sbjct: 343 TIATEVHPA 351



>NP_055059
          Length = 1211

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TIATEVRPA 9
            T+A EVRP+
Sbjct: 1127 TVAMEVRPS 1135



>NP_006006
          Length = 2285

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TIATEVRPA 9
            T ATE RPA
Sbjct: 1440 TAATERRPA 1448



>NP_002448
          Length = 5179

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IATEVRPA 9
            +ATEV PA
Sbjct: 4869 LATEVNPA 4876



>NP_001245258
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 774 TVATEIR 780



>NP_001245260
          Length = 779

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 673 TVATEIR 679



>NP_071361
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TIATEVRP 8
          T AT+VRP
Sbjct: 81 TSATDVRP 88



>NP_001245259
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 595 TVATEIR 601



>NP_818932
          Length = 779

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 673 TVATEIR 679



>NP_036288
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 775 TVATEIR 781



>XP_005260382
          Length = 732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 626 TVATEIR 632



>XP_005260381
          Length = 744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 638 TVATEIR 644



>XP_006723804
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 713 TVATEIR 719



>XP_005260380
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 735 TVATEIR 741



>XP_006723803
          Length = 853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 747 TVATEIR 753



>XP_005260379
          Length = 867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 761 TVATEIR 767



>XP_005260378
          Length = 868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 762 TVATEIR 768



>XP_005260377
          Length = 869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 763 TVATEIR 769



>XP_006723802
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 774 TVATEIR 780



>XP_005260376
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 774 TVATEIR 780



>XP_006723801
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 775 TVATEIR 781



>XP_006723800
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 775 TVATEIR 781



>XP_006723799
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 775 TVATEIR 781



>XP_006723798
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIATEVR 7
           T+ATE+R
Sbjct: 810 TVATEIR 816



>NP_060128
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IATEVRP 8
           IAT VRP
Sbjct: 339 IATNVRP 345



>XP_005267827
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IATEVRP 8
           IAT VRP
Sbjct: 339 IATNVRP 345



>XP_005267826
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   IATEVRP 8
           IAT VRP
Sbjct: 353 IATNVRP 359



>NP_055690
          Length = 1648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TIATEVRP 8
           T+A  VRP
Sbjct: 360 TVAVRVRP 367



>NP_009165
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATEVRPA 9
           AT+V+PA
Sbjct: 178 ATQVKPA 184



>NP_001268356
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATEVRPA 9
           AT+V+PA
Sbjct: 168 ATQVKPA 174



>NP_001268354
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATEVRPA 9
           AT+V+PA
Sbjct: 150 ATQVKPA 156



>NP_061980
          Length = 173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TIATEVRP 8
          T+A +VRP
Sbjct: 37 TVAFDVRP 44



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.121    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 488,193
Number of extensions: 699
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)