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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
NP_588608                                                              18    1935
NP_115804                                                              17    2528
NP_848509                                                              17    2528
XP_006724772                                                           17    2528
XP_006710459                                                           17    2528
XP_005245803                                                           17    2528
XP_005245802                                                           17    2528
NP_001973                                                              16    7355
NP_001077430                                                           15    9605
NP_775907                                                              15    9605
NP_006280                                                              15    9605
NP_001192                                                              15    9605
XP_003960168                                                           15    9605
XP_005258866                                                           15    9605
XP_005271458                                                           15    9605
XP_005271457                                                           15    9605
XP_006716915                                                           15    9605
XP_005251621                                                           15    9605
XP_006714354                                                           15    9605
XP_934596                                                              15    9605
XP_001722188                                                           15    9605
NP_620143                                                              15    9605

>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   HILAALTI 9
           HILAALTI
Sbjct: 231 HILAALTI 238



>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   HILAALTI 9
           HILAALTI
Sbjct: 231 HILAALTI 238



>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   HILAALTI 9
           HILAALTI
Sbjct: 231 HILAALTI 238



>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   HILAALTI 9
           HILAALTI
Sbjct: 231 HILAALTI 238



>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   HILAALTI 9
           HILAALTI
Sbjct: 231 HILAALTI 238



>NP_588608
          Length = 354

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  THILAALTI 9
          TH+LAAL +
Sbjct: 81 THLLAALAV 89



>NP_115804
          Length = 1810

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    THILAALT 8
            TH+LAA+T
Sbjct: 1686 THMLAAIT 1693



>NP_848509
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  THILAALTI 9
          TH+LAAL +
Sbjct: 77 THLLAALVL 85



>XP_006724772
          Length = 1605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    THILAALT 8
            TH+LAA+T
Sbjct: 1481 THMLAAIT 1488



>XP_006710459
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  THILAALTI 9
          TH+LAAL +
Sbjct: 77 THLLAALVL 85



>XP_005245803
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  THILAALTI 9
          TH+LAAL +
Sbjct: 77 THLLAALVL 85



>XP_005245802
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  THILAALTI 9
          TH+LAAL +
Sbjct: 77 THLLAALVL 85



>NP_001973
          Length = 1342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   THILAALTI 9
           TH+  ALT+
Sbjct: 640 THLTMALTV 648



>NP_001077430
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    THILAA 6
            TH+LAA
Sbjct: 1153 THVLAA 1158



>NP_775907
          Length = 1518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    THILAA 6
            TH+LAA
Sbjct: 1148 THVLAA 1153



>NP_006280
          Length = 2541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    THILAAL 7
            +H+LAAL
Sbjct: 1962 SHVLAAL 1968



>NP_001192
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   THILAALTI 9
           +HI AAL+I
Sbjct: 275 SHIRAALSI 283



>XP_003960168
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  HILAALTI 9
          H+L+A+T+
Sbjct: 26 HMLSAMTV 33



>XP_005258866
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    THILAA 6
            TH+LAA
Sbjct: 1116 THVLAA 1121



>XP_005271458
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HILAALTI 9
           H LAAL+I
Sbjct: 222 HYLAALSI 229



>XP_005271457
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HILAALTI 9
           H LAAL+I
Sbjct: 222 HYLAALSI 229



>XP_006716915
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    THILAAL 7
            +H+LAAL
Sbjct: 1962 SHVLAAL 1968



>XP_005251621
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    THILAAL 7
            +H+LAAL
Sbjct: 1962 SHVLAAL 1968



>XP_006714354
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   THILAALTI 9
           +HI AAL+I
Sbjct: 275 SHIRAALSI 283



>XP_934596
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  HILAALTI 9
          H+L+A+T+
Sbjct: 26 HMLSAMTV 33



>XP_001722188
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  HILAALTI 9
          H+L+A+T+
Sbjct: 26 HMLSAMTV 33



>NP_620143
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HILAALTI 9
           H LAAL+I
Sbjct: 222 HYLAALSI 229



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.137    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,269
Number of extensions: 414
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)