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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     390
NP_115543                                                              17    2528
NP_002194                                                              17    2528
XP_006721041                                                           17    2528
XP_006721040                                                           17    2528
XP_005255739                                                           17    2528
NP_001077430                                                           16    5631
NP_775907                                                              16    5631
XP_005258866                                                           16    5631
NP_000426                                                              16    7355
NP_009187                                                              16    7355
XP_005259981                                                           16    7355
XP_006718490                                                           16    7355
NP_001138683                                                           16    7355
NP_001156806                                                           15    9605
NP_620135                                                              15    9605
NP_001156807                                                           15    9605
NP_001105                                                              15    9605
XP_005255842                                                           15    9605
XP_006721191                                                           15    9605
XP_005255841                                                           15    9605
XP_005255840                                                           15    9605
XP_005255839                                                           15    9605
XP_005255837                                                           15    9605
XP_005255838                                                           15    9605
XP_005255836                                                           15    9605

>NP_004251
          Length = 1208

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TGVLVEFNE 9
            TGVLVEF+E
Sbjct: 1024 TGVLVEFSE 1032



>NP_115543
          Length = 813

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVLVEFNE 9
           G L+EFNE
Sbjct: 600 GELIEFNE 607



>NP_002194
          Length = 1181

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TGVLVEFNE 9
           TG++V+F+E
Sbjct: 839 TGIVVDFSE 847



>XP_006721041
          Length = 680

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVLVEFNE 9
           G L+EFNE
Sbjct: 467 GELIEFNE 474



>XP_006721040
          Length = 661

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVLVEFNE 9
           G L+EFNE
Sbjct: 448 GELIEFNE 455



>XP_005255739
          Length = 823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVLVEFNE 9
           G L+EFNE
Sbjct: 610 GELIEFNE 617



>NP_001077430
          Length = 1523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGVLVEFNE 9
           +G+L +FNE
Sbjct: 275 SGLLCQFNE 283



>NP_775907
          Length = 1518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGVLVEFNE 9
           +G+L +FNE
Sbjct: 275 SGLLCQFNE 283



>XP_005258866
          Length = 1486

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGVLVEFNE 9
           +G+L +FNE
Sbjct: 275 SGLLCQFNE 283



>NP_000426
          Length = 2321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GVLVEFNE 9
            GVL E NE
Sbjct: 1154 GVLCEINE 1161



>NP_009187
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TGVLVEFNE 9
          +G+L  FNE
Sbjct: 87 SGLLASFNE 95



>XP_005259981
          Length = 2269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GVLVEFNE 9
            GVL E NE
Sbjct: 1102 GVLCEINE 1109



>XP_006718490
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TGVLVEFNE 9
          +G+L  FNE
Sbjct: 87 SGLLASFNE 95



>NP_001138683
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TGVLVEFNE 9
          +G+L  FNE
Sbjct: 65 SGLLASFNE 73



>NP_001156806
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGVLVEFNE 9
           TG   EFNE
Sbjct: 489 TGTNPEFNE 497



>NP_620135
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGVLVEFNE 9
           TG   EFNE
Sbjct: 467 TGTNPEFNE 475



>NP_001156807
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGVLVEFNE 9
           TG   EFNE
Sbjct: 467 TGTNPEFNE 475



>NP_001105
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



>XP_005255842
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 762 GVMVEFS 768



>XP_006721191
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 790 GVMVEFS 796



>XP_005255841
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



>XP_005255840
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



>XP_005255839
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



>XP_005255837
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



>XP_005255838
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



>XP_005255836
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GVLVEFN 8
           GV+VEF+
Sbjct: 962 GVMVEFS 968



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.139    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,909
Number of extensions: 835
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)