Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_037473                                                              17    4312
NP_071394                                                              17    4312
NP_001177410                                                           17    4312
NP_689982                                                              17    4312
XP_006722779                                                           17    4312
XP_006722778                                                           17    4312
XP_005259585                                                           17    4312
XP_006722777                                                           17    4312
NP_997244                                                              16    5631
NP_056141                                                              16    5631
NP_001164108                                                           16    5631
NP_002843                                                              16    5631
NP_001077415                                                           16    5631
XP_005264468                                                           16    5631
XP_005264467                                                           16    5631
XP_005277570                                                           16    5631
XP_005277569                                                           16    5631
XP_006711309                                                           16    5631
XP_005277568                                                           16    5631
XP_005277567                                                           16    5631
NP_653337                                                              16    5631
NP_001139334                                                           16    7355
NP_001193900                                                           16    7355
NP_002828                                                              16    7355
NP_001103224                                                           16    7355
NP_001138502                                                           16    7355
NP_001193901                                                           16    7355
NP_775271                                                              16    7355
NP_057029                                                              16    7355
NP_001268389                                                           16    7355
NP_001268386                                                           16    7355
NP_001268387                                                           16    7355
XP_006723864                                                           16    7355
XP_005260471                                                           16    7355
XP_006719592                                                           16    7355
XP_006719591                                                           16    7355
NP_000194                                                              15    9605
NP_852478                                                              15    9605
NP_001243725                                                           15    9605
NP_612154                                                              15    9605
NP_060876                                                              15    9605
NP_004523                                                              15    9605
NP_001248327                                                           15    9605
NP_002551                                                              15    9605
NP_001361                                                              15    9605
NP_079030                                                              15    9605
NP_945343                                                              15    9605
XP_006717041                                                           15    9605
XP_005248660                                                           15    9605
XP_005248658                                                           15    9605
XP_006713944                                                           15    9605
XP_006712019                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1314 TCRSTSFNV 1322
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1314 TCRSTSFNV 1322
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1383 TCRSTSFNV 1391
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1383 TCRSTSFNV 1391
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1324 TCRSTSFNV 1332
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1393 TCRSTSFNV 1401
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1393 TCRSTSFNV 1401
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGRSTSFNV 9
            T RSTSFNV
Sbjct: 1393 TCRSTSFNV 1401
>NP_037473
          Length = 396

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GRSTSFNV 9
          G+ST FNV
Sbjct: 34 GKSTFFNV 41
>NP_071394
          Length = 1339

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGRSTSF 7
           TGR TSF
Sbjct: 793 TGRGTSF 799
>NP_001177410
          Length = 1275

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGRSTSF 7
           TGR TSF
Sbjct: 729 TGRGTSF 735
>NP_689982
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  SFN
Sbjct: 128 TGRRVSFN 135
>XP_006722779
          Length = 335

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  SFN
Sbjct: 174 TGRRVSFN 181
>XP_006722778
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  SFN
Sbjct: 174 TGRRVSFN 181
>XP_005259585
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  SFN
Sbjct: 128 TGRRVSFN 135
>XP_006722777
          Length = 751

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  SFN
Sbjct: 174 TGRRVSFN 181
>NP_997244
          Length = 3169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  TGRSTSF 7
          TG STSF
Sbjct: 14 TGNSTSF 20
>NP_056141
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 926 GRSKSFN 932
>NP_001164108
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 925 GRSKSFN 931
>NP_002843
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           +GR T FN+
Sbjct: 330 SGRLTGFNI 338
>NP_001077415
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGRSTSFNV 9
          TG+ST+F +
Sbjct: 85 TGKSTAFQL 93
>XP_005264468
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGRSTSFNV 9
           TG+ST+F +
Sbjct: 112 TGKSTAFQL 120
>XP_005264467
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGRSTSFNV 9
          TG+ST+F +
Sbjct: 70 TGKSTAFQL 78
>XP_005277570
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 773 GRSKSFN 779
>XP_005277569
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 773 GRSKSFN 779
>XP_006711309
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 926 GRSKSFN 932
>XP_005277568
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 925 GRSKSFN 931
>XP_005277567
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GRSTSFN 8
           GRS SFN
Sbjct: 926 GRSKSFN 932
>NP_653337
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGRSTSFNV 9
           TG+ST+F +
Sbjct: 112 TGKSTAFQL 120
>NP_001139334
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  GRSTSFNV 9
          GR  SFN+
Sbjct: 5  GRGQSFNI 12
>NP_001193900
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GRSTSFNV 9
            GRS  FNV
Sbjct: 1235 GRSYQFNV 1242
>NP_002828
          Length = 1997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GRSTSFNV 9
            GRS  FNV
Sbjct: 1325 GRSYQFNV 1332
>NP_001103224
          Length = 2215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GRSTSFNV 9
            GRS  FNV
Sbjct: 1543 GRSYQFNV 1550
>NP_001138502
          Length = 1692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           TGR T+F +
Sbjct: 681 TGRLTNFKI 689
>NP_001193901
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GRSTSFNV 9
            GRS  FNV
Sbjct: 1235 GRSYQFNV 1242
>NP_775271
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           T +ST FNV
Sbjct: 155 TYKSTQFNV 163
>NP_057029
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           T +ST FNV
Sbjct: 155 TYKSTQFNV 163
>NP_001268389
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           T +ST FNV
Sbjct: 155 TYKSTQFNV 163
>NP_001268386
          Length = 251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TGRSTSFNV 9
          T +ST FNV
Sbjct: 41 TYKSTQFNV 49
>NP_001268387
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           T +ST FNV
Sbjct: 184 TYKSTQFNV 192
>XP_006723864
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           T +ST FNV
Sbjct: 155 TYKSTQFNV 163
>XP_005260471
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGRSTSFNV 9
           T +ST FNV
Sbjct: 155 TYKSTQFNV 163
>XP_006719592
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GRSTSFNV 9
            GRS  FNV
Sbjct: 1325 GRSYQFNV 1332
>XP_006719591
          Length = 2230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GRSTSFNV 9
            GRS  FNV
Sbjct: 1543 GRSYQFNV 1550
>NP_000194
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  S+N
Sbjct: 103 TGRGLSYN 110
>NP_852478
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSTSFNV 9
           R+T+FNV
Sbjct: 417 RNTTFNV 423
>NP_001243725
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  +FN
Sbjct: 162 TGRCVAFN 169
>NP_612154
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TGRSTSF 7
           TGR T+F
Sbjct: 119 TGRGTTF 125
>NP_060876
          Length = 5412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    TGRSTSF 7
            TGR T+F
Sbjct: 4406 TGRGTTF 4412
>NP_004523
          Length = 1176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TGRSTSF 7
           TGR T+F
Sbjct: 170 TGRGTTF 176
>NP_001248327
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  +FN
Sbjct: 146 TGRCVAFN 153
>NP_002551
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  +FN
Sbjct: 146 TGRCVAFN 153
>NP_001361
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGRSTSFNV 9
            TG ST+F V
Sbjct: 4124 TGHSTNFVV 4132
>NP_079030
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STSFNV 9
           STSFN+
Sbjct: 165 STSFNI 170
>NP_945343
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GRSTSFN 8
           GR+TSF+
Sbjct: 503 GRATSFD 509
>XP_006717041
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSTSFNV 9
           GR T+F+V
Sbjct: 679 GRKTNFSV 686
>XP_005248660
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  STSFNV 9
          STSFN+
Sbjct: 13 STSFNI 18
>XP_005248658
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STSFNV 9
           STSFN+
Sbjct: 165 STSFNI 170
>XP_006713944
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   TGRSTSFN 8
           TGR  S+N
Sbjct: 103 TGRGLSYN 110
>XP_006712019
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGRSTSFNV 9
            TG ST+F V
Sbjct: 4124 TGHSTNFVV 4132
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.120    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 457,318
Number of extensions: 736
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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