Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           21     175
NP_000170                                                              21     175
NP_001268422                                                           21     175
NP_001268423                                                           21     175
XP_005264328                                                           21     175
NP_004645                                                              18    1482
NP_001034680                                                           18    1482
NP_001034679                                                           18    1482
XP_005272733                                                           18    1482
XP_005272732                                                           18    1482
NP_060552                                                              16    5631
NP_001154180                                                           16    5631
NP_073622                                                              16    5631
NP_002627                                                              16    5631
XP_006724360                                                           16    5631
XP_006724359                                                           16    5631
XP_005261762                                                           16    5631
XP_005261761                                                           16    5631
XP_006719561                                                           16    5631
NP_942153                                                              16    5631
NP_055527                                                              16    7355
NP_001276980                                                           16    7355
NP_001276979                                                           16    7355
NP_001276981                                                           16    7355
NP_037414                                                              16    7355
NP_001041666                                                           16    7355
NP_001019554                                                           16    7355
NP_060385                                                              16    7355
NP_055718                                                              16    7355
NP_001059                                                              16    7355
NP_055402                                                              16    7355
NP_001184216                                                           16    7355
NP_115553                                                              16    7355
XP_006721170                                                           16    7355
XP_006721169                                                           16    7355
XP_005255780                                                           16    7355
XP_006719739                                                           16    7355
XP_006719738                                                           16    7355
XP_005269272                                                           16    7355
XP_006719533                                                           16    7355
XP_005265484                                                           16    7355
NP_001013372                                                           16    7355
NP_001005239                                                           16    7355
NP_001167535                                                           15    9605
NP_001167534                                                           15    9605
NP_001167536                                                           15    9605
NP_001167537                                                           15    9605
NP_056934                                                              15    9605
NP_075598                                                              15    9605
NP_075594                                                              15    9605
NP_075593                                                              15    9605
NP_001167538                                                           15    9605
NP_060037                                                              15    9605
NP_002198                                                              15    9605
NP_899068                                                              15    9605
NP_055240                                                              15    9605
NP_055325                                                              15    9605
NP_149015                                                              15    9605
NP_001124427                                                           15    9605
NP_056133                                                              15    9605
NP_060959                                                              15    9605
NP_037472                                                              15    9605
XP_006722772                                                           15    9605
XP_006722771                                                           15    9605
XP_005272522                                                           15    9605
XP_006722770                                                           15    9605
XP_006722769                                                           15    9605
XP_006722768                                                           15    9605
XP_005272521                                                           15    9605
XP_005251980                                                           15    9605
XP_006715989                                                           15    9605
XP_005245393                                                           15    9605
XP_006711515                                                           15    9605
XP_006711514                                                           15    9605
XP_006711513                                                           15    9605
NP_039224                                                              15    9605
>NP_001268421
          Length = 1230

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TGNGALKRK 9
           TGNG+LKRK
Sbjct: 175 TGNGSLKRK 183
>NP_000170
          Length = 1360

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TGNGALKRK 9
           TGNG+LKRK
Sbjct: 305 TGNGSLKRK 313
>NP_001268422
          Length = 1058

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TGNGALKRK 9
          TGNG+LKRK
Sbjct: 3  TGNGSLKRK 11
>NP_001268423
          Length = 1058

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TGNGALKRK 9
          TGNG+LKRK
Sbjct: 3  TGNGSLKRK 11
>XP_005264328
          Length = 1261

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TGNGALKRK 9
           TGNG+LKRK
Sbjct: 206 TGNGSLKRK 214
>NP_004645
          Length = 2555

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            GNG LKRK
Sbjct: 2408 GNGDLKRK 2415
>NP_001034680
          Length = 2554

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            GNG LKRK
Sbjct: 2407 GNGDLKRK 2414
>NP_001034679
          Length = 2570

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            GNG LKRK
Sbjct: 2407 GNGDLKRK 2414
>XP_005272733
          Length = 2559

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            GNG LKRK
Sbjct: 2412 GNGDLKRK 2419
>XP_005272732
          Length = 2575

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            GNG LKRK
Sbjct: 2412 GNGDLKRK 2419
>NP_060552
          Length = 1133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGNGALKR 8
           TGN +LKR
Sbjct: 421 TGNWSLKR 428
>NP_001154180
          Length = 1075

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGNGALKR 8
           TGN +LKR
Sbjct: 363 TGNWSLKR 370
>NP_073622
          Length = 1501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNG L+R+
Sbjct: 863 GNGILRRR 870
>NP_002627
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGNGALKR 8
           TG+GAL R
Sbjct: 343 TGDGALTR 350
>XP_006724360
          Length = 885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNG L+R+
Sbjct: 161 GNGILRRR 168
>XP_006724359
          Length = 1424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNG L+R+
Sbjct: 863 GNGILRRR 870
>XP_005261762
          Length = 1481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNG L+R+
Sbjct: 757 GNGILRRR 764
>XP_005261761
          Length = 1587

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNG L+R+
Sbjct: 863 GNGILRRR 870
>XP_006719561
          Length = 875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGNGALKR 8
           TGN +LKR
Sbjct: 421 TGNWSLKR 428
>NP_942153
          Length = 1349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNG L+R+
Sbjct: 711 GNGILRRR 718
>NP_055527
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            G GAL+R+
Sbjct: 1385 GEGALRRR 1392
>NP_001276980
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGNGALKRK 9
           TG G  KRK
Sbjct: 642 TGKGKWKRK 650
>NP_001276979
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGNGALKRK 9
           TG G  KRK
Sbjct: 642 TGKGKWKRK 650
>NP_001276981
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGNGALKRK 9
           TG G  KRK
Sbjct: 642 TGKGKWKRK 650
>NP_037414
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGNGALKRK 9
           TG G  KRK
Sbjct: 655 TGKGKWKRK 663
>NP_001041666
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGNGALKRK 9
           TG G  KRK
Sbjct: 642 TGKGKWKRK 650
>NP_001019554
          Length = 2385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGNGALK 7
           TGNGA++
Sbjct: 609 TGNGAVQ 615
>NP_060385
          Length = 579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           TGN + KRK
Sbjct: 503 TGNKSSKRK 511
>NP_055718
          Length = 2363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGNGALK 7
           TGNGA++
Sbjct: 609 TGNGAVQ 615
>NP_001059
          Length = 1621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GNGALKRK 9
            G GA KRK
Sbjct: 1536 GRGAKKRK 1543
>NP_055402
          Length = 446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  GNGALKRK 9
          G GALK K
Sbjct: 92 GGGALKAK 99
>NP_001184216
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TGNGAL 6
          TGNGA+
Sbjct: 55 TGNGAI 60
>NP_115553
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GNGALKRK 9
           G G LKRK
Sbjct: 193 GQGHLKRK 200
>XP_006721170
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            G GAL+R+
Sbjct: 1385 GEGALRRR 1392
>XP_006721169
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            G GAL+R+
Sbjct: 1385 GEGALRRR 1392
>XP_005255780
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GNGALKRK 9
            G GAL+R+
Sbjct: 1385 GEGALRRR 1392
>XP_006719739
          Length = 2306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGNGALK 7
           TGNGA++
Sbjct: 552 TGNGAVQ 558
>XP_006719738
          Length = 2340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGNGALK 7
           TGNGA++
Sbjct: 586 TGNGAVQ 592
>XP_005269272
          Length = 2356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGNGALK 7
           TGNGA++
Sbjct: 609 TGNGAVQ 615
>XP_006719533
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           TGN + KRK
Sbjct: 446 TGNKSSKRK 454
>XP_005265484
          Length = 1626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GNGALKRK 9
            G GA KRK
Sbjct: 1541 GRGAKKRK 1548
>NP_001013372
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TGNGAL 6
          TGNGA+
Sbjct: 55 TGNGAI 60
>NP_001005239
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TGNGAL 6
          TGNGA+
Sbjct: 55 TGNGAI 60
>NP_001167535
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 806 NGGLKRR 812
>NP_001167534
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 814 NGGLKRR 820
>NP_001167536
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 814 NGGLKRR 820
>NP_001167537
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 727 NGGLKRR 733
>NP_056934
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 814 NGGLKRR 820
>NP_075598
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 816 NGGLKRR 822
>NP_075594
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 725 NGGLKRR 731
>NP_075593
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 727 NGGLKRR 733
>NP_001167538
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NGALKRK 9
           NG LKR+
Sbjct: 847 NGGLKRR 853
>NP_060037
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGNGALKRK 9
          TG+GA+ R+
Sbjct: 15 TGSGAVPRQ 23
>NP_002198
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GNGALKRK 9
           GNGAL+ +
Sbjct: 344 GNGALEEQ 351
>NP_899068
          Length = 895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  GNGALKRK 9
          GN ALK K
Sbjct: 36 GNSALKDK 43
>NP_055240
          Length = 1065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  GNGALKRK 9
          GN ALK K
Sbjct: 36 GNSALKDK 43
>NP_055325
          Length = 4935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    TGNGALKR 8
            TG G L+R
Sbjct: 1659 TGGGGLRR 1666
>NP_149015
          Length = 5142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    TGNGALKR 8
            TG G L+R
Sbjct: 1659 TGGGGLRR 1666
>NP_001124427
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 735 TKNGSFKKK 743
>NP_056133
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 577 TKNGSFKKK 585
>NP_060959
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TGNGALKRK 9
            TGN  +KR+
Sbjct: 1841 TGNNFVKRR 1849
>NP_037472
          Length = 818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GNGALKR 8
           GNG+L R
Sbjct: 745 GNGSLSR 751
>XP_006722772
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 577 TKNGSFKKK 585
>XP_006722771
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 577 TKNGSFKKK 585
>XP_005272522
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 650 TKNGSFKKK 658
>XP_006722770
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 907 TKNGSFKKK 915
>XP_006722769
          Length = 1361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 923 TKNGSFKKK 931
>XP_006722768
          Length = 1361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 923 TKNGSFKKK 931
>XP_005272521
          Length = 1426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGNGALKRK 9
           T NG+ K+K
Sbjct: 988 TKNGSFKKK 996
>XP_005251980
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  GNGALKRK 9
          GN ALK K
Sbjct: 36 GNSALKDK 43
>XP_006715989
          Length = 5148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    TGNGALKR 8
            TG G L+R
Sbjct: 1659 TGGGGLRR 1666
>XP_005245393
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TGNGALKRK 9
            TGN  +KR+
Sbjct: 1841 TGNNFVKRR 1849
>XP_006711515
          Length = 2904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TGNGALKRK 9
            TGN  +KR+
Sbjct: 1841 TGNNFVKRR 1849
>XP_006711514
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TGNGALKRK 9
            TGN  +KR+
Sbjct: 1841 TGNNFVKRR 1849
>XP_006711513
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TGNGALKRK 9
            TGN  +KR+
Sbjct: 1841 TGNNFVKRR 1849
>NP_039224
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  TGNGAL 6
          TGNGA+
Sbjct: 38 TGNGAV 43
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.129    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 809,607
Number of extensions: 1590
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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