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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_001398                                                              18    1935
NP_060959                                                              17    2528
XP_005245394                                                           17    2528
XP_005245393                                                           17    2528
XP_006711515                                                           17    2528
XP_006711514                                                           17    2528
XP_006711513                                                           17    2528
NP_001132960                                                           17    3301
NP_056191                                                              17    3301
NP_733772                                                              17    3301
NP_001276876                                                           17    3301
NP_001276959                                                           17    3301
XP_005264304                                                           17    3301
XP_005264303                                                           17    3301
NP_001548                                                              17    4312
NP_001161770                                                           17    4312
NP_006124                                                              17    4312
XP_005274287                                                           17    4312
XP_005274043                                                           17    4312
XP_006718611                                                           17    4312
XP_006718610                                                           17    4312
XP_005246588                                                           17    4312
XP_005246587                                                           17    4312
NP_001034841                                                           17    4312
NP_940908                                                              16    5631
NP_006161                                                              16    5631
NP_001028886                                                           16    5631
NP_001245239                                                           16    5631
NP_001245237                                                           16    5631
NP_001245238                                                           16    5631
XP_005253748                                                           16    5631
XP_005263036                                                           16    5631
NP_055950                                                              16    7355
XP_005250292                                                           16    7355
NP_787954                                                              15    9605
NP_059130                                                              15    9605
NP_001138426                                                           15    9605
NP_001406                                                              15    9605
XP_005254520                                                           15    9605
XP_006714883                                                           15    9605
XP_006714882                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGLVSKDAM 9
            TGLVSKD M
Sbjct: 1927 TGLVSKDVM 1935



>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGLVSKDAM 9
            TGLVSKD M
Sbjct: 1722 TGLVSKDVM 1730



>NP_001398
          Length = 3312

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   TGLVSKDA 8
           TGLVS+DA
Sbjct: 967 TGLVSEDA 974



>NP_060959
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_005245394
          Length = 1741

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_005245393
          Length = 2663

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_006711515
          Length = 2904

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_006711514
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_006711513
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>NP_001132960
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLVSKDAM 9
           GL+SKD M
Sbjct: 467 GLISKDEM 474



>NP_056191
          Length = 689

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLVSKDAM 9
           GL+SKD M
Sbjct: 466 GLISKDEM 473



>NP_733772
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLVSKDAM 9
           GL+SKD M
Sbjct: 467 GLISKDEM 474



>NP_001276876
          Length = 156

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TGLVSKDAM 9
          TG VSKDA+
Sbjct: 9  TGEVSKDAV 17



>NP_001276959
          Length = 436

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TGLVSKDAM 9
           TG VSKDA+
Sbjct: 289 TGEVSKDAV 297



>XP_005264304
          Length = 569

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLVSKDAM 9
           GL+SKD M
Sbjct: 467 GLISKDEM 474



>XP_005264303
          Length = 689

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLVSKDAM 9
           GL+SKD M
Sbjct: 466 GLISKDEM 473



>NP_001548
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>NP_001161770
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>NP_006124
          Length = 1042

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+S+DAM
Sbjct: 502 GLLSEDAM 509



>XP_005274287
          Length = 1042

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+S+DAM
Sbjct: 502 GLLSEDAM 509



>XP_005274043
          Length = 365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  TGLVSKDAM 9
          TG++S+DA+
Sbjct: 64 TGILSEDAL 72



>XP_006718611
          Length = 433

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  TGLVSKDAM 9
          TG++S+DA+
Sbjct: 64 TGILSEDAL 72



>XP_006718610
          Length = 489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  TGLVSKDAM 9
          TG++S+DA+
Sbjct: 12 TGILSEDAL 20



>XP_005246588
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>XP_005246587
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GLVSKDAM 9
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>NP_001034841
          Length = 541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  TGLVSKDAM 9
          TG++S+DA+
Sbjct: 64 TGILSEDAL 72



>NP_940908
          Length = 679

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKDA 8
           TG+ SKDA
Sbjct: 316 TGISSKDA 323



>NP_006161
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLVSKD 7
           TG++SKD
Sbjct: 462 TGVISKD 468



>NP_001028886
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLVSKD 7
           TG++SKD
Sbjct: 462 TGVISKD 468



>NP_001245239
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLVSKD 7
           TG++SKD
Sbjct: 462 TGVISKD 468



>NP_001245237
          Length = 812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLVSKD 7
           TG++SKD
Sbjct: 466 TGVISKD 472



>NP_001245238
          Length = 845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLVSKD 7
           TG++SKD
Sbjct: 499 TGVISKD 505



>XP_005253748
          Length = 812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLVSKD 7
           TG++SKD
Sbjct: 466 TGVISKD 472



>XP_005263036
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKDA 8
           TG+ SKDA
Sbjct: 133 TGISSKDA 140



>NP_055950
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TGLVSKDAM 9
            TG++SK A+
Sbjct: 1677 TGIISKAAL 1685



>XP_005250292
          Length = 1654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TGLVSKDAM 9
            TG++SK A+
Sbjct: 1319 TGIISKAAL 1327



>NP_787954
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GL+SKD
Sbjct: 869 GLISKD 874



>NP_059130
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GL+SKD
Sbjct: 869 GLISKD 874



>NP_001138426
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GLVSKDA 8
           GL+ KDA
Sbjct: 109 GLIQKDA 115



>NP_001406
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLVSKDA 8
           G+VSKD+
Sbjct: 299 GIVSKDS 305



>XP_005254520
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLVSKD 7
           GL+SKD
Sbjct: 553 GLISKD 558



>XP_006714883
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GLVSKDA 8
           GL+ KDA
Sbjct: 109 GLIQKDA 115



>XP_006714882
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GLVSKDA 8
           GL+ KDA
Sbjct: 109 GLIQKDA 115



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.123    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 484,114
Number of extensions: 828
Number of successful extensions: 55
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)