Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     390
NP_079039                                                              18    1482
NP_996897                                                              18    1482
XP_005271269                                                           18    1482
NP_001123488                                                           17    2528
NP_001123489                                                           17    2528
NP_001170                                                              17    2528
XP_005263062                                                           17    2528
XP_005263061                                                           17    2528
XP_005263060                                                           17    2528
XP_005263059                                                           17    2528
XP_006714283                                                           17    2528
XP_005263056                                                           17    2528
XP_006714282                                                           17    2528
XP_006714281                                                           17    2528
XP_005263054                                                           17    2528
NP_001159395                                                           17    3301
NP_000536                                                              17    3301
NP_000449                                                              17    3301
XP_005253988                                                           17    3301
NP_004470                                                              16    5631
XP_005271428                                                           16    5631
NP_005110                                                              16    5631
NP_001136075                                                           16    7355
NP_055588                                                              16    7355
NP_008832                                                              16    7355
NP_001129198                                                           16    7355
NP_078843                                                              16    7355
XP_005254461                                                           16    7355
XP_006720603                                                           16    7355
XP_006720602                                                           16    7355
XP_006716461                                                           16    7355
XP_005273698                                                           16    7355
XP_005273697                                                           16    7355
XP_005273696                                                           16    7355
XP_005273695                                                           16    7355
XP_005273694                                                           16    7355
XP_005273693                                                           16    7355
XP_005273692                                                           16    7355
XP_006716460                                                           16    7355
XP_006716459                                                           16    7355
XP_005268609                                                           16    7355
XP_005268608                                                           16    7355
XP_005268607                                                           16    7355
XP_005268606                                                           16    7355
XP_005268605                                                           16    7355
XP_005268604                                                           16    7355
NP_002290                                                              15    9605
NP_065801                                                              15    9605
>NP_115803
          Length = 1156

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGLNQSRMG 9
            TGLNQSR G
Sbjct: 1067 TGLNQSRTG 1075
>NP_079039
          Length = 848

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TGLNQSRM 8
          TG NQSRM
Sbjct: 82 TGANQSRM 89
>NP_996897
          Length = 545

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TGLNQSRM 8
          TG NQSRM
Sbjct: 82 TGANQSRM 89
>XP_005271269
          Length = 783

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  TGLNQSRM 8
          TG NQSRM
Sbjct: 82 TGANQSRM 89
>NP_001123488
          Length = 389

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>NP_001123489
          Length = 367

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>NP_001170
          Length = 378

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263062
          Length = 353

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263061
          Length = 356

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263060
          Length = 357

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263059
          Length = 363

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_006714283
          Length = 368

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263056
          Length = 378

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_006714282
          Length = 379

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_006714281
          Length = 390

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263054
          Length = 400

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLNQSRMG 9
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>NP_001159395
          Length = 531

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TGLNQS +
Sbjct: 143 TGLNQSHL 150
>NP_000536
          Length = 631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TGLNQS +
Sbjct: 137 TGLNQSHL 144
>NP_000449
          Length = 557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TGLNQS +
Sbjct: 143 TGLNQSHL 150
>XP_005253988
          Length = 662

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TGLNQS +
Sbjct: 137 TGLNQSHL 144
>NP_004470
          Length = 342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGLNQSR 7
           TG+N+SR
Sbjct: 288 TGMNESR 294
>XP_005271428
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGLNQSRMG 9
           TG ++SR+G
Sbjct: 420 TGFDKSRLG 428
>NP_005110
          Length = 955

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGLNQSRMG 9
           TG ++SR+G
Sbjct: 807 TGFDKSRLG 815
>NP_001136075
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>NP_055588
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>NP_008832
          Length = 2548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TG+ QSR+
Sbjct: 804 TGIRQSRL 811
>NP_001129198
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>NP_078843
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005254461
          Length = 2600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TG+ QSR+
Sbjct: 785 TGIRQSRL 792
>XP_006720603
          Length = 2619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TG+ QSR+
Sbjct: 804 TGIRQSRL 811
>XP_006720602
          Length = 2619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLNQSRM 8
           TG+ QSR+
Sbjct: 804 TGIRQSRL 811
>XP_006716461
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273698
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273697
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273696
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273695
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273694
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273693
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273692
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_006716460
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_006716459
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TGLNQSRM 8
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005268609
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>XP_005268608
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>XP_005268607
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>XP_005268606
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>XP_005268605
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>XP_005268604
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGLNQSRMG 9
           TGL + R+G
Sbjct: 155 TGLREPRLG 163
>NP_002290
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    GLNQSRM 8
            GLN+SR+
Sbjct: 1654 GLNKSRL 1660
>NP_065801
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLNQSRM 8
           GLN++RM
Sbjct: 715 GLNRARM 721
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.126    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,423
Number of extensions: 402
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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