Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001274103                                                           17    4312
NP_000343                                                              17    4312
NP_150229                                                              17    4312
NP_005679                                                              17    4312
XP_005257495                                                           17    4312
XP_005257489                                                           17    4312
XP_006718349                                                           17    4312
XP_005247116                                                           17    4312
XP_005247115                                                           17    4312
NP_001166206                                                           17    4312
NP_056383                                                              17    4312
NP_001155155                                                           16    5631
NP_733764                                                              16    5631
NP_653273                                                              16    5631
NP_004906                                                              16    5631
NP_997511                                                              16    5631
NP_058198                                                              16    5631
NP_997512                                                              16    5631
NP_997510                                                              16    5631
NP_997057                                                              16    5631
NP_003777                                                              16    5631
NP_036213                                                              16    5631
XP_005257820                                                           16    5631
XP_006714638                                                           16    5631
XP_006714637                                                           16    5631
NP_001135977                                                           16    5631
NP_071452                                                              16    5631
NP_005912                                                              16    7355
NP_000483                                                              16    7355
NP_689618                                                              16    7355
NP_569079                                                              16    7355
NP_064520                                                              16    7355
NP_001269285                                                           16    7355
NP_060720                                                              16    7355
NP_055127                                                              16    7355
NP_599028                                                              16    7355
NP_439897                                                              16    7355
NP_006176                                                              16    7355
NP_001166033                                                           16    7355
NP_065166                                                              16    7355
NP_001273490                                                           16    7355
XP_006723895                                                           16    7355
XP_006718869                                                           16    7355
XP_006718633                                                           16    7355
XP_006718632                                                           16    7355
XP_006718631                                                           16    7355
XP_006718630                                                           16    7355
XP_006718629                                                           16    7355
XP_006718628                                                           16    7355
XP_006718627                                                           16    7355
XP_006718626                                                           16    7355
XP_006718625                                                           16    7355
XP_006716420                                                           16    7355
XP_006716419                                                           16    7355
XP_006715905                                                           16    7355
XP_005249289                                                           16    7355
XP_005248577                                                           16    7355
XP_005248576                                                           16    7355
XP_005248487                                                           16    7355
NP_001138631                                                           16    7355
NP_116222                                                              15    9605
NP_660187                                                              15    9605
NP_149163                                                              15    9605
NP_115972                                                              15    9605
NP_000383                                                              15    9605
NP_001012661                                                           15    9605
NP_775871                                                              15    9605
XP_006717694                                                           15    9605
XP_006717693                                                           15    9605
XP_005245608                                                           15    9605
NP_997234                                                              15    9605
>NP_001274103
          Length = 1582

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 831 SGGQRQRIS 839
>NP_000343
          Length = 1581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 830 SGGQRQRIS 838
>NP_150229
          Length = 1359

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 604 SGGQRQRIS 612
>NP_005679
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 686 SGGQRQRIS 694
>XP_005257495
          Length = 265

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1 TGAQRKR 7
         TGA+RKR
Sbjct: 3 TGARRKR 9
>XP_005257489
          Length = 424

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1 TGAQRKR 7
         TGA+RKR
Sbjct: 3 TGARRKR 9
>XP_006718349
          Length = 1646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 830 SGGQRQRIS 838
>XP_005247116
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 686 SGGQRQRIS 694
>XP_005247115
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+RIS
Sbjct: 686 SGGQRQRIS 694
>NP_001166206
          Length = 525

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TG +RK++S
Sbjct: 57 TGGRRKKVS 65
>NP_056383
          Length = 567

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TG +RK++S
Sbjct: 57 TGGRRKKVS 65
>NP_001155155
          Length = 1060

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           T AQR+R+S
Sbjct: 991 THAQRRRLS 999
>NP_733764
          Length = 815

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           T AQR+R+S
Sbjct: 746 THAQRRRLS 754
>NP_653273
          Length = 1139

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TGAQRKRIS 9
            T AQR+R+S
Sbjct: 1070 THAQRRRLS 1078
>NP_004906
          Length = 678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 218 SGGQRKRLA 226
>NP_997511
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 196 SGGQRKRLA 204
>NP_058198
          Length = 666

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 218 SGGQRKRLA 226
>NP_997512
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 215 SGGQRKRLA 223
>NP_997510
          Length = 668

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 220 SGGQRKRLA 228
>NP_997057
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 229 SGGQRKRLA 237
>NP_003777
          Length = 1527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+R+S
Sbjct: 752 SGGQRQRVS 760
>NP_036213
          Length = 640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AQRKRIS 9
           AQRKR+S
Sbjct: 574 AQRKRLS 580
>XP_005257820
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QR+R+S
Sbjct: 688 SGGQRQRVS 696
>XP_006714638
          Length = 585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AQRKRIS 9
           AQRKR+S
Sbjct: 519 AQRKRLS 525
>XP_006714637
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AQRKRIS 9
           AQRKR+S
Sbjct: 574 AQRKRLS 580
>NP_001135977
          Length = 646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 202 SGGQRKRLA 210
>NP_071452
          Length = 646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G QRKR++
Sbjct: 202 SGGQRKRLA 210
>NP_005912
          Length = 1512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G +RKR+S
Sbjct: 268 GVRRKRVS 275
>NP_000483
          Length = 1480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGAQRKRIS 9
           +G QR RIS
Sbjct: 549 SGGQRARIS 557
>NP_689618
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G QR+R+S
Sbjct: 881 GLQRRRVS 888
>NP_569079
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  GAQRKRIS 9
          GA+R+R+S
Sbjct: 68 GAKRRRLS 75
>NP_064520
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  GAQRKRIS 9
          GA+R+R+S
Sbjct: 68 GAKRRRLS 75
>NP_001269285
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TGA+RK+ S
Sbjct: 2  TGAKRKKKS 10
>NP_060720
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G +RKR+S
Sbjct: 564 SGKKRKRVS 572
>NP_055127
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TG++ KR+S
Sbjct: 85 TGSKSKRVS 93
>NP_599028
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TGA+RK+ S
Sbjct: 2  TGAKRKKKS 10
>NP_439897
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TGA+RK+ S
Sbjct: 2  TGAKRKKKS 10
>NP_006176
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>NP_001166033
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G +RKR+S
Sbjct: 540 SGKKRKRVS 548
>NP_065166
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G+QR R+S
Sbjct: 240 GSQRSRVS 247
>NP_001273490
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1969 TRQQRKRVS 1977
>XP_006723895
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G+QR R+S
Sbjct: 240 GSQRSRVS 247
>XP_006718869
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TGAQRKRIS 9
          TG++ KR+S
Sbjct: 28 TGSKSKRVS 36
>XP_006718633
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1969 TRQQRKRVS 1977
>XP_006718632
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718631
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718630
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718629
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718628
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718627
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718626
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006718625
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TGAQRKRIS 9
            T  QRKR+S
Sbjct: 1983 TRQQRKRVS 1991
>XP_006716420
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G +RKR+S
Sbjct: 564 SGKKRKRVS 572
>XP_006716419
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G +RKR+S
Sbjct: 564 SGKKRKRVS 572
>XP_006715905
          Length = 1588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGAQRKRIS 9
           +G QR RIS
Sbjct: 657 SGGQRARIS 665
>XP_005249289
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  GAQRKRIS 9
          GA+R+R+S
Sbjct: 68 GAKRRRLS 75
>XP_005248577
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G +RKR+S
Sbjct: 105 GVRRKRVS 112
>XP_005248576
          Length = 1375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G +RKR+S
Sbjct: 131 GVRRKRVS 138
>XP_005248487
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAQRKRIS 9
           G QR+R+S
Sbjct: 840 GLQRRRVS 847
>NP_001138631
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G +RKR+S
Sbjct: 543 SGKKRKRVS 551
>NP_116222
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  TGAQRKRI 8
          TG  RKR+
Sbjct: 5  TGGSRKRL 12
>NP_660187
          Length = 1344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G Q++RIS
Sbjct: 635 SGGQKQRIS 643
>NP_149163
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G Q++RIS
Sbjct: 635 SGGQKQRIS 643
>NP_115972
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G Q++RIS
Sbjct: 635 SGGQKQRIS 643
>NP_000383
          Length = 1545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G Q++RIS
Sbjct: 762 SGGQKQRIS 770
>NP_001012661
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GAQRKRIS 9
          GAQ +R+S
Sbjct: 41 GAQSRRVS 48
>NP_775871
          Length = 8384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGAQRKRIS 9
           TG  RKR S
Sbjct: 401 TGGNRKRSS 409
>XP_006717694
          Length = 895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G Q++RIS
Sbjct: 762 SGGQKQRIS 770
>XP_006717693
          Length = 1313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGAQRKRIS 9
           +G Q++RIS
Sbjct: 530 SGGQKQRIS 538
>XP_005245608
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  TGAQRKRI 8
          TG  RKR+
Sbjct: 5  TGGSRKRL 12
>NP_997234
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GAQRKRI 8
           GAQR+R+
Sbjct: 104 GAQRERL 110
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.123    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 496,312
Number of extensions: 998
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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