Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     390
XP_005262424                                                           20     390
NP_001135389                                                           17    2528
NP_000757                                                              17    3301
NP_612152                                                              17    3301
XP_006715715                                                           17    3301
NP_060594                                                              17    4312
XP_006721291                                                           17    4312
XP_006721290                                                           17    4312
XP_005256079                                                           17    4312
XP_005256078                                                           17    4312
NP_000753                                                              16    7355
NP_001229510                                                           16    7355
NP_065816                                                              16    7355
NP_002909                                                              16    7355
NP_085079                                                              16    7355
NP_000755                                                              16    7355
NP_940873                                                              16    7355
XP_006723636                                                           16    7355
XP_006722894                                                           16    7355
XP_006722893                                                           16    7355
XP_006722892                                                           16    7355
XP_006722781                                                           16    7355
XP_005272524                                                           16    7355
XP_006717206                                                           16    7355
XP_005252108                                                           16    7355
XP_006710573                                                           16    7355
XP_006710572                                                           16    7355
XP_006710571                                                           16    7355
XP_006710570                                                           16    7355
XP_006710569                                                           16    7355
XP_006710568                                                           16    7355
XP_006710567                                                           16    7355
XP_006710566                                                           16    7355
XP_005245859                                                           16    7355
NP_005383                                                              16    7355
NP_001136245                                                           15    9605
NP_001136239                                                           15    9605
NP_001136236                                                           15    9605
NP_001136244                                                           15    9605
NP_001136238                                                           15    9605
NP_001136240                                                           15    9605
NP_001136243                                                           15    9605
NP_001136242                                                           15    9605
NP_001136235                                                           15    9605
NP_001136237                                                           15    9605
NP_001136241                                                           15    9605
NP_149045                                                              15    9605
NP_001001931                                                           15    9605
NP_110443                                                              15    9605
NP_004520                                                              15    9605
NP_001230715                                                           15    9605
NP_001138890                                                           15    9605
NP_001273620                                                           15    9605
NP_079091                                                              15    9605
NP_066288                                                              15    9605
NP_000527                                                              15    9605
NP_001230714                                                           15    9605
XP_006724234                                                           15    9605
XP_005261462                                                           15    9605
XP_006718013                                                           15    9605
XP_006710993                                                           15    9605
XP_005271292                                                           15    9605
XP_005271291                                                           15    9605
XP_006710992                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TFTASQTG 8
            TFTASQTG
Sbjct: 1921 TFTASQTG 1928
>XP_005262424
          Length = 2875

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TFTASQTG 8
            TFTASQTG
Sbjct: 1716 TFTASQTG 1723
>NP_001135389
          Length = 1335

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TFTASQTGQ 9
           T TASQTG+
Sbjct: 564 TTTASQTGK 572
>NP_000757
          Length = 494

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTASQTGQ 9
           FTA+ TGQ
Sbjct: 211 FTATSTGQ 218
>NP_612152
          Length = 2849

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TFTASQTG 8
           +FTASQ+G
Sbjct: 259 SFTASQSG 266
>XP_006715715
          Length = 2023

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   TFTASQTG 8
           +FTASQ+G
Sbjct: 259 SFTASQSG 266
>NP_060594
          Length = 774

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TFTASQTG 8
           TFT SQ G
Sbjct: 441 TFTVSQAG 448
>XP_006721291
          Length = 715

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TFTASQTG 8
           TFT SQ G
Sbjct: 441 TFTVSQAG 448
>XP_006721290
          Length = 774

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TFTASQTG 8
           TFT SQ G
Sbjct: 441 TFTVSQAG 448
>XP_005256079
          Length = 774

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TFTASQTG 8
           TFT SQ G
Sbjct: 441 TFTVSQAG 448
>XP_005256078
          Length = 774

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TFTASQTG 8
           TFT SQ G
Sbjct: 441 TFTVSQAG 448
>NP_000753
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTASQTGQ 9
           FT++ TGQ
Sbjct: 211 FTSTSTGQ 218
>NP_001229510
          Length = 944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FTASQT 7
          FTASQT
Sbjct: 31 FTASQT 36
>NP_065816
          Length = 5183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3850 TFTASQ 3855
>NP_002909
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TASQTG 8
           TASQTG
Sbjct: 124 TASQTG 129
>NP_085079
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTASQTGQ 9
           FT++ TGQ
Sbjct: 160 FTSTSTGQ 167
>NP_000755
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTASQTGQ 9
           FT++ TGQ
Sbjct: 211 FTSTSTGQ 218
>NP_940873
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ASQTGQ 9
           ASQTGQ
Sbjct: 692 ASQTGQ 697
>XP_006723636
          Length = 944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FTASQT 7
          FTASQT
Sbjct: 31 FTASQT 36
>XP_006722894
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TASQTG 8
          TASQTG
Sbjct: 15 TASQTG 20
>XP_006722893
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TASQTG 8
          TASQTG
Sbjct: 15 TASQTG 20
>XP_006722892
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TASQTG 8
           TASQTG
Sbjct: 124 TASQTG 129
>XP_006722781
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ASQTGQ 9
           ASQTGQ
Sbjct: 692 ASQTGQ 697
>XP_005272524
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ASQTGQ 9
           ASQTGQ
Sbjct: 743 ASQTGQ 748
>XP_006717206
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TFTASQTGQ 9
            TFT +Q G+
Sbjct: 997  TFTGAQAGR 1005
>XP_005252108
          Length = 1097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TFTASQTGQ 9
            TFT +Q G+
Sbjct: 1032 TFTGAQAGR 1040
>XP_006710573
          Length = 5177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3844 TFTASQ 3849
>XP_006710572
          Length = 5188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3855 TFTASQ 3860
>XP_006710571
          Length = 5194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3861 TFTASQ 3866
>XP_006710570
          Length = 5195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3862 TFTASQ 3867
>XP_006710569
          Length = 5212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3879 TFTASQ 3884
>XP_006710568
          Length = 5221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3888 TFTASQ 3893
>XP_006710567
          Length = 5222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3889 TFTASQ 3894
>XP_006710566
          Length = 5222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3889 TFTASQ 3894
>XP_005245859
          Length = 5223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    TFTASQ 6
            TFTASQ
Sbjct: 3890 TFTASQ 3895
>NP_005383
          Length = 1096

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    TFTASQTGQ 9
            TFT +Q G+
Sbjct: 1031 TFTGAQAGR 1039
>NP_001136245
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 430 FTVTQTG 436
>NP_001136239
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 415 FTVTQTG 421
>NP_001136236
          Length = 1957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136244
          Length = 1677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136238
          Length = 1952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136240
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 430 FTVTQTG 436
>NP_001136243
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 457 FTVTQTG 463
>NP_001136242
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136235
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 457 FTVTQTG 463
>NP_001136237
          Length = 1886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136241
          Length = 1790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 464 FTVTQTG 470
>NP_149045
          Length = 1955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001001931
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  TFTASQTG 8
          TFT  +TG
Sbjct: 58 TFTGKKTG 65
>NP_110443
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TFTASQTG 8
           +FT +QTG
Sbjct: 336 SFTRAQTG 343
>NP_004520
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TFTASQTGQ 9
           +FT SQT Q
Sbjct: 391 SFTPSQTRQ 399
>NP_001230715
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TFTASQT 7
           TFT SQT
Sbjct: 361 TFTNSQT 367
>NP_001138890
          Length = 2481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TASQTGQ 9
            TAS+TG+
Sbjct: 1840 TASETGE 1846
>NP_001273620
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TFTASQTGQ 9
           +FT SQT Q
Sbjct: 388 SFTPSQTRQ 396
>NP_079091
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TFTASQT 7
           TFT++QT
Sbjct: 195 TFTSAQT 201
>NP_066288
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TFTASQTGQ 9
           TFT + +GQ
Sbjct: 332 TFTVTPSGQ 340
>NP_000527
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TFTASQT 7
           TFT SQT
Sbjct: 361 TFTNSQT 367
>NP_001230714
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TFTASQT 7
           TFT SQT
Sbjct: 361 TFTNSQT 367
>XP_006724234
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TASQTGQ 9
            TAS+TG+
Sbjct: 1722 TASETGE 1728
>XP_005261462
          Length = 2473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TASQTGQ 9
            TAS+TG+
Sbjct: 1840 TASETGE 1846
>XP_006718013
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTASQTG 8
           FT +QTG
Sbjct: 452 FTVTQTG 458
>XP_006710993
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TFTASQTG 8
           +FT +QTG
Sbjct: 336 SFTRAQTG 343
>XP_005271292
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TFTASQTG 8
           +FT +QTG
Sbjct: 336 SFTRAQTG 343
>XP_005271291
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TFTASQTG 8
           +FT +QTG
Sbjct: 336 SFTRAQTG 343
>XP_006710992
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TFTASQTG 8
           +FT +QTG
Sbjct: 336 SFTRAQTG 343
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.109    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,843
Number of extensions: 568
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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