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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              18    1135
NP_001087241                                                           18    1135
XP_005265799                                                           18    1135
XP_005265798                                                           18    1135
XP_005265797                                                           18    1135
NP_001274278                                                           16    5631
NP_001275521                                                           16    5631
NP_061121                                                              16    5631
NP_001275519                                                           16    5631
XP_005265380                                                           16    5631
NP_570118                                                              15    9605
NP_570116                                                              15    9605
NP_001035939                                                           15    9605
NP_005959                                                              15    9605
NP_060839                                                              15    9605
NP_001138680                                                           15    9605
NP_060024                                                              15    9605
NP_060099                                                              15    9605
NP_689690                                                              15    9605
NP_112480                                                              15    9605
XP_005258610                                                           15    9605
XP_005272540                                                           15    9605
XP_005272539                                                           15    9605
XP_005272538                                                           15    9605
XP_005272537                                                           15    9605
XP_005272536                                                           15    9605
XP_005272535                                                           15    9605
XP_005270636                                                           15    9605
XP_005270635                                                           15    9605

>NP_000213
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TFKQ VQLI
Sbjct: 916 TFKQIVQLI 924



>NP_001087241
          Length = 972

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TFKQ VQLI
Sbjct: 912 TFKQIVQLI 920



>XP_005265799
          Length = 973

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TFKQ VQLI
Sbjct: 913 TFKQIVQLI 921



>XP_005265798
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TFKQ VQLI
Sbjct: 916 TFKQIVQLI 924



>XP_005265797
          Length = 977

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TFKQ VQLI
Sbjct: 917 TFKQIVQLI 925



>NP_001274278
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+Q+ QLI
Sbjct: 195 TFRQTSQLI 203



>NP_001275521
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+Q+ QLI
Sbjct: 268 TFRQTSQLI 276



>NP_061121
          Length = 754

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+Q+ QLI
Sbjct: 419 TFRQTSQLI 427



>NP_001275519
          Length = 754

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+Q+ QLI
Sbjct: 419 TFRQTSQLI 427



>XP_005265380
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+Q+ QLI
Sbjct: 418 TFRQTSQLI 426



>NP_570118
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+ +VQL+
Sbjct: 102 TFQHTVQLL 110



>NP_570116
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+ +VQL+
Sbjct: 102 TFQHTVQLL 110



>NP_001035939
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TFKQSVQLI 9
           TF+Q  QLI
Sbjct: 259 TFRQHSQLI 267



>NP_005959
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 250 TFEQSIEAV 258



>NP_060839
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TFKQSVQLI 9
          T KQ+VQL+
Sbjct: 68 TRKQTVQLL 76



>NP_001138680
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TFKQSVQLI 9
          T KQ+VQL+
Sbjct: 68 TRKQTVQLL 76



>NP_060024
          Length = 1801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TFKQSVQL 8
          TFK +VQL
Sbjct: 82 TFKLTVQL 89



>NP_060099
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TFKQSVQLI 9
           TFK SVQ +
Sbjct: 117 TFKVSVQWV 125



>NP_689690
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TFKQSVQLI 9
           TF+Q  QLI
Sbjct: 259 TFRQHSQLI 267



>NP_112480
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 211 TFEQSIEAV 219



>XP_005258610
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TFKQSVQLI 9
           TF+Q  QLI
Sbjct: 259 TFRQHSQLI 267



>XP_005272540
          Length = 571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  TFKQSVQLI 9
          TF+QS++ +
Sbjct: 91 TFEQSIEAV 99



>XP_005272539
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 130 TFEQSIEAV 138



>XP_005272538
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 130 TFEQSIEAV 138



>XP_005272537
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 211 TFEQSIEAV 219



>XP_005272536
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 250 TFEQSIEAV 258



>XP_005272535
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TFKQSVQLI 9
           TF+QS++ +
Sbjct: 250 TFEQSIEAV 258



>XP_005270636
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TFKQSVQLI 9
          TFK SVQ +
Sbjct: 50 TFKVSVQWV 58



>XP_005270635
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TFKQSVQLI 9
          TFK SVQ +
Sbjct: 50 TFKVSVQWV 58



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.134    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 286,844
Number of extensions: 421
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)