Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_789765                                                              20     299
NP_001123914                                                           20     299
NP_005334                                                              20     299
NP_004976                                                              20     299
NP_203524                                                              20     299
NP_002515                                                              20     299
XP_006725199                                                           20     299
XP_006719132                                                           20     299
XP_006718280                                                           20     299
NP_001136408                                                           19     665
NP_631918                                                              19     665
NP_036382                                                              18    1482
NP_006266                                                              17    2528
NP_001238851                                                           17    2528
NP_001238847                                                           17    2528
NP_001238846                                                           17    2528
NP_056461                                                              17    2528
NP_001238850                                                           17    2528
NP_001010942                                                           17    2528
NP_005617                                                              17    2528
NP_004666                                                              17    2528
XP_006711090                                                           17    2528
XP_006710866                                                           17    2528
NP_001010935                                                           17    2528
NP_002875                                                              17    2528
NP_001078518                                                           17    4312
NP_036351                                                              17    4312
NP_001239019                                                           17    4312
NP_001983                                                              17    4312
NP_853510                                                              17    4312
XP_005247286                                                           17    4312
XP_005247285                                                           17    4312
NP_002877                                                              16    5631
NP_741995                                                              16    5631
NP_067006                                                              16    5631
NP_001258115                                                           16    5631
NP_059986                                                              16    5631
NP_066361                                                              16    5631
NP_055125                                                              16    7355
NP_001019764                                                           16    7355
NP_001007528                                                           16    7355
XP_005261500                                                           16    7355
XP_005261499                                                           16    7355
XP_005261498                                                           16    7355
XP_005252126                                                           16    7355
XP_006717213                                                           16    7355
XP_005252124                                                           16    7355
XP_005252123                                                           16    7355
NP_001935                                                              16    7355
NP_001240781                                                           15    9605
NP_006585                                                              15    9605
NP_001240782                                                           15    9605
NP_000098                                                              15    9605
NP_060867                                                              15    9605
NP_787103                                                              15    9605
NP_057069                                                              15    9605
XP_006723630                                                           15    9605
XP_005266744                                                           15    9605
XP_005266743                                                           15    9605
XP_005252865                                                           15    9605
XP_006718224                                                           15    9605
XP_006713315                                                           15    9605
XP_006713314                                                           15    9605
XP_006713313                                                           15    9605
XP_005270438                                                           15    9605
NP_001812                                                              15    9605
>NP_789765
          Length = 170

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>NP_001123914
          Length = 189

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>NP_005334
          Length = 189

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>NP_004976
          Length = 188

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>NP_203524
          Length = 189

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>NP_002515
          Length = 189

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>XP_006725199
          Length = 170

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>XP_006719132
          Length = 189

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>XP_006718280
          Length = 170

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  TEYRLVVVG 9
          TEY+LVVVG
Sbjct: 2  TEYKLVVVG 10
>NP_001136408
          Length = 543

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   EYRLVVVG 9
           EYRLV+VG
Sbjct: 305 EYRLVIVG 312
>NP_631918
          Length = 672

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   EYRLVVVG 9
           EYRLV+VG
Sbjct: 434 EYRLVIVG 441
>NP_036382
          Length = 204

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          +YRLVVVG
Sbjct: 14 KYRLVVVG 21
>NP_006266
          Length = 344

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TEYRLVV 7
           TEYRL+V
Sbjct: 108 TEYRLIV 114
>NP_001238851
          Length = 137

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_001238847
          Length = 142

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_001238846
          Length = 142

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_056461
          Length = 184

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_001238850
          Length = 165

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_001010942
          Length = 184

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_005617
          Length = 494

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TEYRLVV 7
           TEYRL+V
Sbjct: 102 TEYRLIV 108
>NP_004666
          Length = 229

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          +YR+VVVG
Sbjct: 37 DYRVVVVG 44
>XP_006711090
          Length = 229

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          +YR+VVVG
Sbjct: 37 DYRVVVVG 44
>XP_006710866
          Length = 184

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_001010935
          Length = 184

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_002875
          Length = 184

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY+LVV+G
Sbjct: 3  EYKLVVLG 10
>NP_001078518
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          Y+LVVVG
Sbjct: 14 YKLVVVG 20
>NP_036351
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          Y+LVVVG
Sbjct: 14 YKLVVVG 20
>NP_001239019
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          Y+LVVVG
Sbjct: 14 YKLVVVG 20
>NP_001983
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TEYRLVVV 8
          TEYRLV +
Sbjct: 67 TEYRLVSI 74
>NP_853510
          Length = 233

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EYRLVVVG 9
          EY+ VVVG
Sbjct: 41 EYKAVVVG 48
>XP_005247286
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          Y+LVVVG
Sbjct: 14 YKLVVVG 20
>XP_005247285
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          Y+LVVVG
Sbjct: 14 YKLVVVG 20
>NP_002877
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY++VV+G
Sbjct: 3  EYKVVVLG 10
>NP_741995
          Length = 213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          ++RL+V+G
Sbjct: 8  QFRLIVIG 15
>NP_067006
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY++VV+G
Sbjct: 3  EYKVVVLG 10
>NP_001258115
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY++VV+G
Sbjct: 3  EYKVVVLG 10
>NP_059986
          Length = 217

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          ++RL+V+G
Sbjct: 8  QFRLIVIG 15
>NP_066361
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          EY++VV+G
Sbjct: 3  EYKVVVLG 10
>NP_055125
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          YR+VV+G
Sbjct: 20 YRMVVLG 26
>NP_001019764
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EYRLVVVG 9
          EY+LVV G
Sbjct: 72 EYKLVVDG 79
>NP_001007528
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EYRLVVVG 9
          ++RLV++G
Sbjct: 30 QHRLVIIG 37
>XP_005261500
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          YR+VV+G
Sbjct: 20 YRMVVLG 26
>XP_005261499
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          YR+VV+G
Sbjct: 20 YRMVVLG 26
>XP_005261498
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  YRLVVVG 9
          YR+VV+G
Sbjct: 32 YRMVVLG 38
>XP_005252126
          Length = 298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YR+VV+G
Sbjct: 97  YRIVVLG 103
>XP_006717213
          Length = 320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YR+VV+G
Sbjct: 97  YRIVVLG 103
>XP_005252124
          Length = 333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YR+VV+G
Sbjct: 97  YRIVVLG 103
>XP_005252123
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YR+VV+G
Sbjct: 97  YRIVVLG 103
>NP_001935
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TEYRLVVVG 9
           + YRLVV G
Sbjct: 231 SSYRLVVSG 239
>NP_001240781
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YRL++VG
Sbjct: 519 YRLLLVG 525
>NP_006585
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YRL++VG
Sbjct: 519 YRLLLVG 525
>NP_001240782
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YRL++VG
Sbjct: 420 YRLLLVG 426
>NP_000098
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YRLVVVG 9
           Y L+VVG
Sbjct: 348 YNLIVVG 354
>NP_060867
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EYRLVVVG 9
          EY  VVVG
Sbjct: 40 EYSYVVVG 47
>NP_787103
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEYRLVVVG 9
           T+ RL+V+G
Sbjct: 262 TKGRLIVIG 270
>NP_057069
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YRLVVVG 9
           YRL VVG
Sbjct: 406 YRLSVVG 412
>XP_006723630
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YRLVVVG 9
           YRL VVG
Sbjct: 244 YRLSVVG 250
>XP_005266744
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEYRLVVVG 9
           T+ RL+V+G
Sbjct: 139 TKGRLIVIG 147
>XP_005266743
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEYRLVVVG 9
           T+ RL+V+G
Sbjct: 139 TKGRLIVIG 147
>XP_005252865
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YRLVVVG 9
           Y L+VVG
Sbjct: 159 YNLIVVG 165
>XP_006718224
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YRLVVVG 9
           Y L+VVG
Sbjct: 348 YNLIVVG 354
>XP_006713315
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EYRLVVVG 9
          EY  VVVG
Sbjct: 40 EYSYVVVG 47
>XP_006713314
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EYRLVVVG 9
          EY  VVVG
Sbjct: 40 EYSYVVVG 47
>XP_006713313
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EYRLVVVG 9
          EY  VVVG
Sbjct: 40 EYSYVVVG 47
>XP_005270438
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YRLVVVG 9
           YRL++VG
Sbjct: 415 YRLLLVG 421
>NP_001812
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  TEYRLVVVG 9
          TE+ +V++G
Sbjct: 7  TEFDVVIIG 15
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.146    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 440,634
Number of extensions: 696
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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